The Relativistic Electrodynamics Least Action Principles Revisited: New Charged Point Particle and Hadronic String Models Analysis

The classical relativistic least action principle is revisited from the vacuum field theory approach. New physically motivated versions of relativistic Lorentz type forces are derived, a new relativistic hadronic string model is proposed and analyzed in detail.Comment: n/

The Cyprus Women’s Health Research (COHERE) initiative: normative data from the SF-36v2 questionnaire for reproductive aged women from the Eastern Mediterranean

Purpose: Describe the health-related quality of life for a representative cohort of women aged 18–55 in Northern Cyprus. Methods: We utilised the SF-36-Health-Survey-version-2 (SF-36v2) questionnaire as part of the COHERE Initiative study to calculate the eight physical and mental subscale scores, as well as the two overall summary measures for physical and mental health, where we present results using Cyprus-specific scoring as well as scores based on the test developers’ algorithms. We examined associations between sociodemographic characteristics for both scores. Results: A total of 7089 women fully completed the SF-36v2 questionnaire (mean age = 36.9), which was reliable and valid in this population. We observed better physical health in ages 18–25 compared to 46–55 (53.32 vs. 46.72 (p < 0.001)) and better mental health in women aged 46–55 compared to 18–25 (52.07 vs. 47.95 (p < 0.001)). Women in employment had better physical and mental health compared to those who were unemployed (physical: 50.25 vs 49.95, p < 0.001 and mental: 50.25 vs 49.24, p = 0.083) and scores increased as educational attainment increased (physical: 47.55 for primary to 51.58 for postgraduate, mental: 48.88 to 50.59, p < 0.001). Turkish Cypriot women had higher scores than Turkish women (physical: 50.42 vs 49.30, mental: 50.43 vs 49.10, p < 0.001). Conclusion: These are the first population normative values published from a large representative sample of women between 18 and 55 years from the Eastern Mediterranean region. We found better physical health in younger women and better mental health in older women. Turkish Cypriot women and non-migrant women had better mental health, and HRQOL was highest in those in paid employment and those with a higher educational achievement

Automation tools to support undertaking scoping reviews.

This paper describes several automation tools and software that can be considered during evidence synthesis projects and provides guidance for their integration in the conduct of scoping reviews. The guidance presented in this work is adapted from the results of a scoping review and consultations with the JBI Scoping Review Methodology group. This paper describes several reliable, validated automation tools and software that can be used to enhance the conduct of scoping reviews. Developments in the automation of systematic reviews, and more recently scoping reviews, are continuously evolving. We detail several helpful tools in order of the key steps recommended by the JBI's methodological guidance for undertaking scoping reviews including team establishment, protocol development, searching, de-duplication, screening titles and abstracts, data extraction, data charting, and report writing. While we include several reliable tools and software that can be used for the automation of scoping reviews, there are some limitations to the tools mentioned. For example, some are available in English only and their lack of integration with other tools results in limited interoperability. This paper highlighted several useful automation tools and software programs to use in undertaking each step of a scoping review. This guidance has the potential to inform collaborative efforts aiming at the development of evidence informed, integrated automation tools and software packages for enhancing the conduct of high-quality scoping reviews

Syrian refugees: The demographic impacts on the republic of Turkey and reflections on the social studies coursebooks

International Symposium on Chaos, Complexity and Leadership, ICCLS 2017 -- 21 October 2017 through 22 October 2017 -- Ankara -- 253619The events taking place in Syria are described as the biggest humanitarian crisis in the world today. Since April 2011, Turkey has helped the people who are running away from Syria’s internal conflict. This situation has caused Turkey to experience the most serious experience of massive human mobility in its history. Syrian refugees, who were previously seen as guests, are becoming permanent as a result of the prolongation of the civil war in Syria. While 8% of the refugees in Turkey live in camps, 92% live in almost everywhere in urban centers with the citizens of Turkey. This has made the issue of refugees an important phenomenon. Syrian refugees have caused many social, economic, psychological, and educational problems in Turkey. This study focuses on how Syrian refugees have an impact on the Republic of Turkey demographically. Also, it is evaluated how the subjects of the migration and Syrian refugees are addressed in social studies coursebooks. © Springer International Publishing AG, part of Springer Nature 2019

Prognostic models in COVID-19 infection that predict severity: a systematic review.

Current evidence on COVID-19 prognostic models is inconsistent and clinical applicability remains controversial. We performed a systematic review to summarize and critically appraise the available studies that have developed, assessed and/or validated prognostic models of COVID-19 predicting health outcomes. We searched six bibliographic databases to identify published articles that investigated univariable and multivariable prognostic models predicting adverse outcomes in adult COVID-19 patients, including intensive care unit (ICU) admission, intubation, high-flow nasal therapy (HFNT), extracorporeal membrane oxygenation (ECMO) and mortality. We identified and assessed 314 eligible articles from more than 40 countries, with 152 of these studies presenting mortality, 66 progression to severe or critical illness, 35 mortality and ICU admission combined, 17 ICU admission only, while the remaining 44 studies reported prediction models for mechanical ventilation (MV) or a combination of multiple outcomes. The sample size of included studies varied from 11 to 7,704,171 participants, with a mean age ranging from 18 to 93 years. There were 353 prognostic models investigated, with area under the curve (AUC) ranging from 0.44 to 0.99. A great proportion of studies (61.5%, 193 out of 314) performed internal or external validation or replication. In 312 (99.4%) studies, prognostic models were reported to be at high risk of bias due to uncertainties and challenges surrounding methodological rigor, sampling, handling of missing data, failure to deal with overfitting and heterogeneous definitions of COVID-19 and severity outcomes. While several clinical prognostic models for COVID-19 have been described in the literature, they are limited in generalizability and/or applicability due to deficiencies in addressing fundamental statistical and methodological concerns. Future large, multi-centric and well-designed prognostic prospective studies are needed to clarify remaining uncertainties

Consensus definition and diagnostic criteria for neonatal encephalopathy-study protocol for a real-time modified delphi study

BACKGROUND: 'Neonatal encephalopathy' (NE) describes a group of conditions in term infants presenting in the earliest days after birth with disturbed neurological function of cerebral origin. NE is aetiologically heterogenous; one cause is peripartum hypoxic ischaemia. Lack of uniformity in the terminology used to describe NE and its diagnostic criteria creates difficulty in the design and interpretation of research and complicates communication with families. The DEFINE study aims to use a modified Delphi approach to form a consensus definition for NE, and diagnostic criteria.METHODS: Directed by an international steering group, we will conduct a systematic review of the literature to assess the terminology used in trials of NE, and with their guidance perform an online Real-time Delphi survey to develop a consensus diagnosis and criteria for NE. A consensus meeting will be held to agree on the final terminology and criteria, and the outcome disseminated widely.DISCUSSION: A clear and consistent consensus-based definition of NE and criteria for its diagnosis, achieved by use of a modified Delphi technique, will enable more comparability of research results and improved communication among professionals and with families.IMPACT: The terms Neonatal Encephalopathy and Hypoxic Ischaemic Encephalopathy tend to be used interchangeably in the literature to describe a term newborn with signs of encephalopathy at birth. This creates difficulty in communication with families and carers, and between medical professionals and researchers, as well as creating difficulty with performance of research. The DEFINE project will use a Real-time Delphi approach to create a consensus definition for the term 'Neonatal Encephalopathy'. A definition formed by this consensus approach will be accepted and utilised by the neonatal community to improve research, outcomes, and parental experience.</p

Consensus definition and diagnostic criteria for neonatal encephalopathy—study protocol for a real-time modified delphi study

Background: ‘Neonatal encephalopathy’ (NE) describes a group of conditions in term infants presenting in the earliest days after birth with disturbed neurological function of cerebral origin. NE is aetiologically heterogenous; one cause is peripartum hypoxic ischaemia. Lack of uniformity in the terminology used to describe NE and its diagnostic criteria creates difficulty in the design and interpretation of research and complicates communication with families. The DEFINE study aims to use a modified Delphi approach to form a consensus definition for NE, and diagnostic criteria. Methods: Directed by an international steering group, we will conduct a systematic review of the literature to assess the terminology used in trials of NE, and with their guidance perform an online Real-time Delphi survey to develop a consensus diagnosis and criteria for NE. A consensus meeting will be held to agree on the final terminology and criteria, and the outcome disseminated widely. Discussion: A clear and consistent consensus-based definition of NE and criteria for its diagnosis, achieved by use of a modified Delphi technique, will enable more comparability of research results and improved communication among professionals and with families. Impact: The terms Neonatal Encephalopathy and Hypoxic Ischaemic Encephalopathy tend to be used interchangeably in the literature to describe a term newborn with signs of encephalopathy at birth. This creates difficulty in communication with families and carers, and between medical professionals and researchers, as well as creating difficulty with performance of research. The DEFINE project will use a Real-time Delphi approach to create a consensus definition for the term ‘Neonatal Encephalopathy’. A definition formed by this consensus approach will be accepted and utilised by the neonatal community to improve research, outcomes, and parental experience

Over 1000 terms have been used to describe evidence synthesis: a scoping review

Objective To inform the development of an evidence synthesis taxonomy, we aimed to identify and examine all classification systems, typologies or taxonomies that have been proposed for evidence synthesis methods. Design Scoping review. Methods This review followed JBI (previously Joanna Briggs Institute) scoping review methodology and was reported according to PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews). Resources that investigated typologies, taxonomies, classification systems and compendia for evidence synthesis within any field were eligible for inclusion. A comprehensive search across MEDLINE (Ovid), Embase (OVID), CINAHL with Full-Text (EBSCO), ERIC (EBSCO), Scopus, Compendex (Elsevier) and JSTOR was performed on 28 April 2022. This was supplemented by citation searching of key articles, contact with experts, targeted searching of organisational websites and additional grey literature searching. Documents were extracted by one reviewer and extractions verified by another reviewer. Data were analysed using frequency counts and a basic qualitative content analysis approach. Results are presented using bar charts, word clouds and narrative summary. Results There were 15 634 titles and abstracts screened, and 703 full texts assessed for eligibility. Ultimately, 446 documents were included, and 49 formal classification systems identified, with the remaining documents presenting structured lists, simple listings or general discussions. Included documents were mostly not field-specific (n=242) or aligned to clinical sciences (n=83); however, public health, education, information technology, law and engineering were also represented. Documents (n=148) mostly included two to three evidence synthesis types, while 22 documents mentioned over 20 types of evidence synthesis. We identified 1010 unique terms to describe a type of evidence synthesis; of these, 742 terms were only mentioned once. Facets that could usefully distinguish (ie, similarities and differences or characteristics) between evidence synthesis approaches were categorised based on similarity into 15 overarching dimensions. These dimensions include review question and foci of interest, discipline/field, perspective, coverage, eligibility criteria, review purpose, methodological principles, theoretical underpinnings/philosophical perspective, resource considerations, compatibility with heterogeneity, sequence planning, analytical synthesis techniques, intended product/output, intended audience and intended impact or influence. Conclusion This scoping review identified numerous unique terms to describe evidence synthesis approaches and many diverse ways to distinguish or categorise review types. These results suggest a need for the evidence synthesis community to organise, categorise and harmonise evidence synthesis approaches and terminology

The Order Effect of Associative and Rule-Based Reasoning Strategies in Design Learning

This study focuses on the role of associative reasoning (AR) and rule-based reasoning (RbR) strategies in students' creativity. An experimental comparison was conducted to test the impact of the order in which students used specific reasoning strategies in a series of design tasks. The results provide insights into the order in which these forms of reasoning can be introduced to students in design studio education. The results indicate that when students first conduct a free exploration of the given design problem before asked to use one of the reasoning strategies above their creative performance is higher. It is proposed that familiar ization with a given problem freely prepare students for a structured design explo ration following either rule-based or associative reasoning strategy. We conclude that the creative performance gets better when students first explore the design problem on their own before getting introduced to a specific form of reasoning strategy. © Springer Nature Switzerland AG 2022. All rights reserved