On the Definition of Gauge Field Operators in Lattice Gauge-Fixed Theories

We address the problem of defining the gauge four-potential on the lattice, in terms of the natural link variables. Different regularized definitions are shown, through non perturbative numerical computation, to converge towards the same continuum renormalized limit.Comment: 8 pages, LaTeX2e/LaTeX209, 3 eps figure

Magnetic structure of Ba(TiO)Cu4_4(PO4_4)4_4 probed using spherical neutron polarimetry

The antiferromagnetic compound Ba(TiO)Cu$_4$(PO$_4$)$_4$ contains square cupola of corner-sharing CuO$_4$ plaquettes, which were proposed to form effective quadrupolar order. To identify the magnetic structure, we have performed spherical neutron polarimetry measurements. Based on symmetry analysis and careful measurements we conclude that the orientation of the Cu$^{2+}$ spins form a non-collinear in-out structure with spins approximately perpendicular to the CuO$_4$ motif. Strong Dzyaloshinskii-Moriya interaction naturally lends itself to explain this phenomenon. The identification of the ground state magnetic structure should serve well for future theoretical and experimental studies into this and closely related compounds.Comment: 9 pages, 4 figure

Conformational constraints on side chains in protein residues increase their information content

Like all other complex biological systems, proteins exhibit properties not seen in free amino acids (i.e., emergent properties). The present investigation arose from the deduction that proteins should offer a good model to approach the reverse phenomenon, namely top-down constraints experienced by protein residues compared to free amino acids. The crystalline structure of profilin Ib, a contractile protein of Acanthamoeba castellanii, was chosen as the object of study and submitted to 2-ns molecular dynamics simulation. The results revealed strong conformational constraints on the side chain of residues compared to the respective free amino acids. A Shannon entropy (SE) analysis of the conformational behavior of the side chains showed in most cases a strong decrease in the SE of the χ1 and χ2 dihedral angles compared to free amino acids. This is equivalent to stating that conformational constraints on the side chain of residues increase their information content and hence recognition specificity compared to free amino acids. In other words, the vastly increased information content of a protein relative to its free monomers is embedded not only in the tertiary structure of the backbone, but also in the conformational behavior of the side chains. The postulated implication is that both backbone and side chains, by virtue of being conformationally constrained, contribute to the recognition specificity of the protein toward other macromolecules and ligand

On the nature of prominence emission observed by SDO/AIA

The Prominence-Corona Transition Region (PCTR) plays a key role in the thermal and pressure equilibrium of solar prominences. Our knowledge of this interface is limited and several major issues remain open, including the thermal structure and, in particular, the maximum temperature of the detectable plasma. The high signal-to-noise ratio of images obtained by the Atmospheric Imaging Assembly (AIA) on NASA's Solar Dynamics Observatory clearly show that prominences are often seen in emission in the 171 and 131 bands. We investigate the temperature sensitivity of these AIA bands for prominence observation, in order to infer the temperature content in an effort to explain the emission. Using the CHIANTI atomic database and previously determined prominence differential emission measure distributions, we build synthetic spectra to establish the main emission-line contributors in the AIA bands. We find that the Fe IX line always dominates the 171 band, even in the absence of plasma at > 10^6 K temperatures, while the 131 band is dominated by Fe VIII. We conclude that the PCTR has sufficient plasma emitting at > 4 10^5 K to be detected by AIA.Comment: accepted Ap

The Supersymmetric Ward-Takahashi Identity in 1-Loop Lattice Perturbation Theory. I. General Procedure

The one-loop corrections to the lattice supersymmetric Ward-Takahashi identity (WTi) are investigated in the off-shell regime. In the Wilson formulation of the N=1 supersymmetric Yang-Mills (SYM) theory, supersymmetry (SUSY) is broken by the lattice, by the Wilson term and is softly broken by the presence of the gluino mass. However, the renormalization of the supercurrent can be realized in a scheme that restores the continuum supersymmetric WTi (once the on-shell condition is imposed). The general procedure used to calculate the renormalization constants and mixing coefficients for the local supercurrent is presented. The supercurrent not only mixes with the gauge invariant operator $T_\mu$. An extra mixing with other operators coming from the WTi appears. This extra mixing survives in the continuum limit in the off-shell regime and cancels out when the on-shell condition is imposed and the renormalized gluino mass is set to zero. Comparison with numerical results are also presented.Comment: 16 pages, 2 figures. Typos error correcte

Predicting drug metabolism: Concepts and challenges

The paper begins with a discussion of the needs and goals of metabolic predictions in early drug research. Major difficulties toward this objective are examined, mainly the various substrate and product selectivities characteristic of drug metabolism. In a second part, we classify and summarize the major in silico methods used to predict drug metabolism. A discrimination is thus made between "local ”and "global ”systems. In the last part of the paper, the program METEOR is presented and evaluated using the published metabolic data of 10 substrate

Hubble Space Telescope Observations of the Oldest Star Clusters in the LMC

We present V, V-I color-magnitude diagrams (CMDs) for three old star clusters in the Large Magellanic Cloud (LMC): NGC 1466, NGC 2257 and Hodge 11. Our data extend about 3 magnitudes below the main-sequence turnoff, allowing us to determine accurate relative ages and the blue straggler frequencies. Based on a differential comparison of the CMDs, any age difference between the three LMC clusters is less than 1.5 Gyr. Comparing their CMDs to those of M 92 and M 3, the LMC clusters, unless their published metallicities are significantly in error, are the same age as the old Galactic globulars. The similar ages to Galactic globulars are shown to be consistent with hierarchial clustering models of galaxy formation. The blue straggler frequencies are also similar to those of Galactic globular clusters. We derive a true distance modulus to the LMC of (m-M)=18.46 +/- 0.09 (assuming (m-M)=14.61 for M 92) using these three LMC clusters.Comment: 22 pages; to be published in Ap

The distance to the LMC cluster Reticulum from the K-band Period-Luminosity-Metallicity relation of RR Lyrae stars

We present new and accurate Near-Infrared J and Ks-band data of the Large Magellanic Cloud cluster Reticulum. Data were collected with SOFI available at NTT and covering an area of approximately (5 x 5) arcmin^2 around the center of the cluster. Current data allowed us to derive accurate mean K-band magnitudes for 21 fundamental and 9 first overtone RR Lyrae stars. On the basis of the semi-empirical K-band Period-Luminosity-Metallicity relation we have recently derived, we find that the absolute distance to this cluster is 18.52 +- 0.005 (random) +- 0.117 (systematic). Note that the current error budget is dominated by systematic uncertainty affecting the absolute zero-point calibration and the metallicity scale.Comment: 14 pages, 2 figures, ApJ accepted. Full resolution figure 1 on request ([email protected]

Nonperturbative Gauge Fixing and Perturbation Theory

We compare the gauge-fixing approach proposed by Jona-Lasinio and Parrinello, and by Zwanziger (JPLZ) with the standard Fadeev-Popov procedure, and demonstrate perturbative equality of gauge-invariant quantities, up to irrelevant terms induced by the cutoff. We also show how a set of local, renormalizable Feynman rules can be constructed for the JPLZ procedure.Comment: 9 pages, latex, version to appear in Phys. Rev.