Marker-Assisted Breeding as Next-Generation Strategy for Genetic Improvement of Productivity and Quality: Can It Be Realized in Cotton?

The dawdling development in genetic improvement of cotton with conventional breeding program is chiefly due to lack of complete knowledge on and precise manipulation of fiber productivity and quality. Naturally available cotton continues to be a resource for the upcoming breeding program, and contemporary technologies to exploit the available natural variation are outlined in this paper for further improvement of fiber. Particularly emphasis is given to application, obstacles, and perspectives of marker-assisted breeding since it appears to be more promising in manipulating novel genes that are available in the cotton germplasm. Deployment of system quantitative genetics in marker-assisted breeding program would be essential to realize its role in cotton. At the same time, role of genetic engineering and in vitro mutagenesis cannot be ruled out in genetic improvement of cotton

Corporate Governance in Latin America

This paper analyzes recent trends of Latin America's institutional development regarding investor protection. In spite of the underdevelopment of the region's financial markets, there is slow movement towards legal reforms intended to protect investors and make regional markets more attractive to investors; current inadequacies in the region's legal institution's generate high levels of ownership concentration, poor access to external equity financing, and narrow equity markets. The evidence in this paper, based on firm-level data for six countries, shows that, like legal protection of investors, appropriate firm-level corporate governance is linked to lower costs for capital, better valuation, performance, and dividend payments across countries. Firms can compensate for their countries' legal deficiencies by distinguishing themselves through improved corporate governance practices, thus increasing transparency and limiting potential conflict between large and minority shareholders. Firms can additionally look for capital by issuing ADRs, as they have in recent years, although this practice undermines local capital markets. In the end, firms and regulators must improve their governance structures and shareholder protections if they are to meet the improved benchmarks of developed nations brought about by Asian, European, and U.S. scandals in recent years

Recent strategies for improving the performance of ionic liquids as battery electrolytes

Ionic liquids (ILs) are widely known for their intriguing properties, such as low flammability, high electrochemical stability, etc., and therefore are considered as promising alternatives to conventional organic solvent-based battery electrolytes. Yet, IL-based electrolytes have rarely been used for practical battery applications, mostly due to their high viscosity and limited transport properties. Recent research efforts attempt to overcome these drawbacks by increasing the salt concentration in electrolytes and exploring the addition of solvents in hybrid ILs, as well as designing solvate IL electrolytes. This review aims to briefly discuss these recent strategies adopted with regard to Li-based and other advanced battery systems. This work also outlines the design of novel ILs where the tuneable chemistry of ILs can play a role in providing a pathway to battery applications

Andrographis paniculata (Burm. f.) wall. ex nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy

Infectious disease (ID) is one of the top-most serious threats to human health globally, further aggravated by antimicrobial resistance and lack of novel immunization options. Andrographis paniculata (Burm. f.) Wall. ex Nees and its metabolites have been long used to treat IDs. Andrographolide, derived from A. paniculata, can inhibit invasive microbes virulence factors and regulate the host immunity. Controlled clinical trials revealed that A. paniculata treatment is safe and efficacious for acute respiratory tract infections like common cold and sinusitis. Hence, A. paniculata, mainly andrographolide, could be considered as an excellent candidate for antimicrobial drug development. Considering the importance, medicinal values, and significant role as antimicrobial agents, this study critically evaluated the antimicrobial therapeutic potency of A. paniculata and its metabolites, focusing on the mechanism of action in inhibiting invasive microbes and biofilm formation. A critical evaluation of the secondary metabolites with the aim of identifying pure compounds that possess antimicrobial functions has further added significant values to this study. Notwithstanding that A. paniculata is a promising source of antimicrobial agents and safe treatment for IDs, further empirical research is warranted

Developing a High-Performing Spinel LiMn2O4 Cathode Material with Unique Morphology, Fast Cycling and Scaled Manufacture

High power application of Li‐battery remains a challenge due to the lack of stable fast‐charging cathode materials. Lithium manganese oxide (LMO) cathode is very promising due to its high operating voltage and fast charging ability; however, the associated Mn‐dissolution is one of the main hindrances to its practical applicability. In this work, we demonstrate for the first time the use of a commercially scalable method through a proprietary Calix flash calcination (CFC) technology to develop high‐performance electrode materials where a novel CXL LMO material was manufactured and tested. CXL LMO|Li metal cell showed a reversible specific capacity of 110 mAh/g with 99% retention after 100 cycles and showed excellent rate performance up to 20C current rate (~20 mA/cm2 current density). CXL LMO|Graphite cell (areal capacity 1 mAh/cm2) was also reported with 86% capacity retention over more than 500 cycles. Cross‐section morphology revealed a unique multi‐layered structure that was retained at the core of the novel LMO material. It obtained lesser Mn dissolution compared to commercial LMO. The scalable synthesis procedure through CFC technology, can be broadly applicable to produce unique electrode morphology as demonstrated here for the CXL LMO representing a promising pathway for electrode manufacturing for high‐power Li‐batteries