Anchored narratives and dialectical argumentation

Trying criminal cases is hard. The problem faced by a judge in court can be phrased in a deceptively simple way though, as follows: in order to come to a verdict, a judge has to apply the rules of law to the facts of the case. In a naïve and often criticized model of legal decision making (reminding of the bouche de la loi view on judges), the verdict is determined by applying the rules of law that match the case facts. This naïve model of legal decision making can be referred to as the subsumption model. A problem with the subsumption model is that neither the rules of law nor the case facts are available to the legal decision maker in a sufficiently well-structured form to make the processes of matching and applying a trivial matter. First, there is the problem of determining what the rules of law and the case facts are. Neither the rules nor the facts are presented to the judge in a precise and unambiguous way. A judge has to interpret the available information about the rules of law and the case facts. Second, even if the rules of law and the case facts would be determined, the processes of matching and applying can be problematic. It can for instance be undetermined whether some case fact falls under a particular rule's condition. Additional classificatory rules are then needed. In general, it can be the case that applying the rules of law leads to conflicting verdicts about the case at hand, or to no verdict at all. In the latter situation, it is to the judge's discretion to fill the gap, in the former, he has to resolve the conflict

Childhood Characteristics of Adolescent Inpatients with Early-Onset and Adolescent-Onset Disruptive Behavior

Childhood characteristics are associated with life-course-persistent antisocial behavior in epidemiological studies in general population samples. The present study examines this association in an inpatient sample. The purpose is to identify easily measurable childhood characteristics that may guide choice of treatment for adolescent psychiatric inpatients with severe disruptive behavior. Patients (N = 203) were divided into two groups with either early-onset (EO) or adolescent-onset (AO) disruptive behavior, based on ages at which professional care was used for disruptive behavior, referral to special education, and criminal offences. Both groups differed on several childhood characteristics. No gender differences in these characteristics were found. Logistic regression analysis indicated that individuals with grade retention in primary school, childhood impulsive behavior, and a history of physical abuse, had the highest probability of being member of the EO group. These characteristics are reasonably easy to identify, likely apply to other clinical samples as well, and may help clinicians to target their treatment

Interferon (IFN)-γ-Inducible Protein-10: Association with Histological Results, Viral Kinetics, and Outcome during Treatment with Pegylated IFN-α2a and Ribavirin for Chronic Hepatitis C Virus Infection

BackgroundWe investigated associations between interferon (IFN)-γ-inducible protein (IP)-10 and liver histological results, viral kinetic response, and treatment outcome in patients infected with hepatitis C virus (HCV) genotypes 1-4 MethodsPlasma IP-10 was monitored before, during, and after treatment with pegylated IFN-α2a and ribavirin in 265 HCV-infected patients ResultsIn univariate analyses, a low baseline IP-10 level was significantly associated with low baseline viral load, rapid viral response (RVR), a sustained viral response (SVR), body mass index <25 kg/m2, and less-pronounced fibrosis, inflammation, and steatosis (for HCV genotypes other than 3). When the results of the univariate analyses were included in multivariate analyses, a low plasma IP-10 level, low baseline viral load, and genotype 2 or 3 infection were independent predictors of an RVR and SVR. IP-10 levels decreased 6 weeks into treatment and remained low in patients with an SVR. By contrast, plasma levels of IP-10 rebounded in patients who had detectable HCV RNA after the completion of treatment. Using cutoff IP-10 levels of 150 and 600 pg/mL for predicting an SVR in patients infected with HCV genotype 1 yielded a specificity and sensitivity of 81% and 95%, respectively ConclusionBaseline IP-10 levels are predictive of the response to HCV treatmen

Hardness of case-based decisions: A formal theory

Stare decisis is a fundamental principle of case-based reasoning. Yet its application varies in complexity and depends, in particular, on whether relevant past decisions agree, or exist at all. The contribution of this paper is a formal treatment of types of the hardness of case-based decisions. The typology of hardness is defined in terms of the arguments for and against the issue to be decided, and their kind of validity (conclusive, presumptive, coherent, incoherent). We apply the typology of hardness to Berman and Hafner's research on the dynamics of case-based reasoning and show formally how the hardness of decisions varies with time

Logical Comparison of Cases

Comparison between cases is a core issue in case-based reasoning. In this paper, we discuss a logical comparison approach in terms of the case model formalism. By logically generalizing the formulas involved in case comparison, our approach identifies analogies, distinctions and relevances. An analogy is a property shared between cases. A distinction is a property of one case ruled out by the other case, and a relevance is a property of one case, and not the other, that is not ruled out by the other case. The comparison approach is applied to HYPO-style comparison (where distinctions and relevances are not separately characterized) and to the temporal dynamics of case-based reasoning using a model of real world cases.</p