To transduce a zebra finch: interrogating behavioral mechanisms in a model system for speech.

The ability to alter neuronal gene expression, either to affect levels of endogenous molecules or to express exogenous ones, is a powerful tool for linking brain and behavior. Scientists continue to finesse genetic manipulation in mice. Yet mice do not exhibit every behavior of interest. For example, Mus musculus do not readily imitate sounds, a trait known as vocal learning and a feature of speech. In contrast, thousands of bird species exhibit this ability. The circuits and underlying molecular mechanisms appear similar between disparate avian orders and are shared with humans. An advantage of studying vocal learning birds is that the neurons dedicated to this trait are nested within the surrounding brain regions, providing anatomical targets for relating brain and behavior. In songbirds, these nuclei are known as the song control system. Molecular function can be interrogated in non-traditional model organisms by exploiting the ability of viruses to insert genetic material into neurons to drive expression of experimenter-defined genes. To date, the use of viruses in the song control system is limited. Here, we review prior successes and test additional viruses for their capacity to transduce basal ganglia song control neurons. These findings provide a roadmap for troubleshooting the use of viruses in animal champions of fascinating behaviors-nowhere better featured than at the 12th International Congress

The impact of charge symmetry and charge independence breaking on the properties of neutrons and protons in isospin-asymmetric nuclear matter

We investigate the effects of charge independence and charge symmetry breaking in neutron-rich matter. We consider neutron and proton properties in isospin-asymmetric matter at normal densities as well as the high-density neutron matter equation of state and the bulk properties of neutron stars. We find charge symmetry and charge independence breaking effects to be very small.Comment: 6 pages, 8 figure

Fracture functions in the very forward limit

This talk gives a brief discussion of extended fracture functions, which parametrise the non-perturbative physics in the target fragmentation region of semi-inclusive DIS. In the forward limit z -> 1, it can be seen that fracture functions can be identified with insertions of composite operators. This enables polarised fracture functions to be used to test a target-independence hypothesis of the ``proton spin effect''.Comment: 4 pages, 3 figures, LaTeX 2e; talk at QCD99 Montpellie

Comment on ``Stripes and the t-J Model''

This is a comment being submitted to Physical Review Letters on a recent letter by Hellberg and Manousakis on stripes in the t-J model.Comment: One reference correcte

Topological Change in Mean Convex Mean Curvature Flow

Consider the mean curvature flow of an (n+1)-dimensional, compact, mean convex region in Euclidean space (or, if n<7, in a Riemannian manifold). We prove that elements of the m-th homotopy group of the complementary region can die only if there is a shrinking S^k x R^(n-k) singularity for some k less than or equal to m. We also prove that for each m from 1 to n, there is a nonempty open set of compact, mean convex regions K in R^(n+1) with smooth boundary for which the resulting mean curvature flow has a shrinking S^m x R^(n-m) singularity.Comment: 19 pages. This version includes a new section proving that certain kinds of mean curvature flow singularities persist under arbitrary small perturbations of the initial surface. Newest update (Oct 2013) fixes some bibliographic reference

Database Analysis to Support Nutrient Criteria Development (Phase I)

The intent of this publication of the Arkansas Water Resources Center is to provide a location whereby a final report on water research to a funding agency can be archived. The Texas Commission on Environmental Quality (TCEQ) contracted with University of Arkansas researchers for a multiple year project titled “Database Analysis to Support Nutrient Criteria Development”. This publication covers the first of three phases of that project and has maintained the original format of the report as submitted to TCEQ. This report can be cited either as an AWRC publication (see below) or directly as the final report to TCEQ

THE WELFARE REFORM BILL AND ITS EFFECTS IN THE SOUTH

Political Economy,

Double window viewing chamber assembly

A viewing chamber which permits observation of a sample retained therein includes a pair of double window assemblies mounted in opposed openings in the walls thereof so that a light beam can directly enter and exit from the chamber. A flexible mounting arrangement for the outer windows of the window assemblies enables the windows to be brought into proper alignment. An electrical heating arrangement prevents fogging of the outer windows whereas desiccated air in the volume between the outer and inner windows prevents fogging of the latter

Simulations of the Fomalhaut System Within Its Local Galactic Environment

Fomalhaut A is among the most well-studied nearby stars and has been discovered to possess a putative planetary object as well as a remarkable eccentric dust belt. This eccentric dust belt has often been interpreted as the dynamical signature of one or more planets that elude direct detection. However, the system also contains two other stellar companions residing ~100,000 AU from Fomalhaut A. We have designed a new symplectic integration algorithm to model the evolution of Fomalhaut A's planetary dust belt in concert with the dynamical evolution of its stellar companions to determine if these companions are likely to have generated the dust belt's morphology. Using our numerical simulations, we find that close encounters between Fomalhaut A and B are expected, with a ~25% probability that the two stars have passed within at least 400 AU of each other at some point. Although the outcomes of such encounter histories are extremely varied, these close encounters nearly always excite the eccentricity of Fomalhaut A's dust belt and occasionally yield morphologies very similar to the observed belt. With these results, we argue that close encounters with Fomalhaut A's stellar companions should be considered a plausible mechanism to explain its eccentric belt, especially in the absence of detected planets capable of sculpting the belt's morphology. More broadly, we can also conclude from this work that very wide binary stars may often generate asymmetries in the stellar debris disks they host.Comment: Accepted to MNRAS, 22 pages, 15 figures, 2 appendice