Simulation Tools for Detector and Instrument Design

The high performance requirements at the European Spallation Source have been driving the technological advances on the neutron detector front. Now more than ever is it important to optimize the design of detectors and instruments, to fully exploit the ESS source brilliance. Most of the simulation tools the neutron scattering community has at their disposal target the instrument optimization until the sample position, with little focus on detectors. The ESS Detector Group has extended the capabilities of existing detector simulation tools to bridge this gap. An extensive software framework has been developed, enabling efficient and collaborative developments of required simulations and analyses -- based on the use of the Geant4 Monte Carlo toolkit, but with extended physics capabilities where relevant (like for Bragg diffraction of thermal neutrons in crystals). Furthermore, the MCPL (Monte Carlo Particle Lists) particle data exchange file format, currently supported for the primary Monte Carlo tools of the community (McStas, Geant4 and MCNP), facilitates the integration of detector simulations with existing simulations of instruments using these software packages. These means offer a powerful set of tools to tailor the detector and instrument design to the instrument application

Expected Performance of TOTEM BLMS at the LHC

The TOTEM experiment at the LHC will operate down to 10 sigma from the beam in the forward region of the CMS experiment. The associated beam loss monitors (BLMs) are crucial to monitor the position of the detectors and to provide a rapid identification of abnormal beam conditions for machine protection purposes. In this paper, the response of the TOTEM BLMs is considered for nominal machine operation and the protection thresholds are defined, withcalculations made of the expected signal fromprotons grazing the TOTEM pot as a function of pot distance from the beam, and the BLM signal from proton collisions at the CMS beam interaction point

Boron-10 lined RPCs for sub-millimeter resolution thermal neutron detectors: Feasibility study in a thermal neutron beam

The results of an experimental feasibility study of a position sensitive thermal neutron detector based on a resistive plate chamber (RPC) are presented. The detector prototype features a thin-gap (0.35 mm) hybrid RPC with an aluminium cathode lined with a 2 ${\mu}$m thick $^{10}B{_4}C$ neutron converter layer enriched in $^{10}B$ and a float glass anode. A detection efficiency of ${\approx}$ 6.2 ${\%}$ was measured for the neutron beam (${\lambda}$ =2.5 ${\AA}$) at normal incidence. A spatial resolution better than 0.5 mm FWHM was demonstrated

Multiple exon skipping strategies to by-pass dystrophin mutations.

Manipulation of dystrophin pre-mRNA processing offers the potential to overcome mutations in the dystrophin gene that would otherwise lead to Duchenne muscular dystrophy. Dystrophin mutations will require the removal of one or more exons to restore the reading frame and in some cases, multiple exon skipping strategies exist to restore dystrophin expression. However, for some small intra-exonic mutations, a third strategy, not applicable to whole exon deletions, may be possible. The removal of only one frame-shifting exon flanking the mutation-carrying exon may restore the reading frame and allow synthesis of a functional dystrophin isoform, providing that no premature termination codons are encountered. For these mutations, the removal of only one exon offers a simpler, cheaper and more feasible alternative approach to the dual exon skipping that would otherwise be considered. We present strategies to by-pass intra-exonic dystrophin mutations that clearly demonstrate the importance of tailoring exon skipping strategies to specific patient mutations

Charge Transfer Properties Through Graphene Layers in Gas Detectors

Graphene is a single layer of carbon atoms arranged in a honeycomb lattice with remarkable mechanical, electrical and optical properties. For the first time graphene layers suspended on copper meshes were installed into a gas detector equipped with a gaseous electron multiplier. Measurements of low energy electron and ion transfer through graphene were conducted. In this paper we describe the sample preparation for suspended graphene layers, the testing procedures and we discuss the preliminary results followed by a prospect of further applications.Comment: 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference with the 21st Symposium on Room-Temperature Semiconductor X-Ray and Gamma-Ray Detectors, 4 pages, 8 figure

Overcoming High Energy Backgrounds at Pulsed Spallation Sources

Instrument backgrounds at neutron scattering facilities directly affect the quality and the efficiency of the scientific measurements that users perform. Part of the background at pulsed spallation neutron sources is caused by, and time-correlated with, the emission of high energy particles when the proton beam strikes the spallation target. This prompt pulse ultimately produces a signal, which can be highly problematic for a subset of instruments and measurements due to the time-correlated properties, and different to that from reactor sources. Measurements of this background have been made at both SNS (ORNL, Oak Ridge, TN, USA) and SINQ (PSI, Villigen, Switzerland). The background levels were generally found to be low compared to natural background. However, very low intensities of high-energy particles have been found to be detrimental to instrument performance in some conditions. Given that instrument performance is typically characterised by S/N, improvements in backgrounds can both improve instrument performance whilst at the same time delivering significant cost savings. A systematic holistic approach is suggested in this contribution to increase the effectiveness of this. Instrument performance should subsequently benefit.Comment: 12 pages, 8 figures. Proceedings of ICANS XXI (International Collaboration on Advanced Neutron Sources), Mito, Japan. 201

What’s sex got to do with it? A family-based investigation of growing up heterosexual during the twentieth century

This paper explores findings from a cross-generational study of the making of heterosexual relationships in East Yorkshire, which has interviewed women and men within extended families. Using a feminist perspective, it examines the relationship between heterosexuality and adulthood, focussing on sexual attraction, courtship, first kisses, first love and first sex, as mediated within family relationships, and at different historical moments. In this way, the contemporary experiences of young people growing up are compared and contrasted with those of mid-lifers and older adults who formed heterosexual relationships within the context of the changing social and sexual mores of the 1960s/1970s, and the upheavals of World War Two

Some Restrictions Abroad Affecting Corporations

A neutron detector concept based on solid layers of boron carbide enriched in 1 B has been in development for the last few years as an alternative for He-3 by collaboration between the ILL, ESS and Linkoping University. This Multi-Grid detector uses layers of aluminum substrates coated with (B4C)-B-10 on both sides that are traversed by the incoming neutrons. Detection is achieved using a gas counter readout principle. By segmenting the substrate and using multiple anode wires, the detector is made inherently position sensitive. This development is aimed primarily at neutron scattering instruments with large detector areas, such as time-of-flight chopper spectrometers. The most recent prototype has been built to be interchangeable with the He-3 detectors of IN6 at ILL. The 1 B detector has an active area of 32 x 48 cm(2). It was installed at the IN6 instrument and operated for several weeks, collecting data in parallel with the regularly scheduled experiments, thus providing the first side-by-side comparison with the conventional He-3 detectors. Results include an efficiency comparison, assessment of the in-detector scattering contribution, sensitivity to gamma-rays and the signal-to-noise ratio in time-of-flight spectra. The good expected performance has been confirmed with the exception of an unexpected background count rate. This has been identified as natural alpha activity in aluminum. New convertor substrates are under study to eliminate this source of background

Wilton B. Persons to Senator James O. Eastland, 19 February 1960

Typed letter signed dated 19 February 1960 from Wilton B. Persons, Assistant to the President, to Eastland, re: Tariff Commission & cotton textile imports, Section 22 of the Agricultural Adjustment Act.https://egrove.olemiss.edu/joecorr_c/1003/thumbnail.jp