The transformation of the Radical Right Gender Gap: The case of the 2014 EP Election

This communication has no abstrac

Parole in jeans: poesia e telematica

abstract not availabl

Airway responsiveness to methacholine: effects of deep inhalations and airway inflammation.

Abstract We determined the dose-response curves to inhaled methacholine (MCh) in 16 asthmatic and 8 healthy subjects with prohibition of deep inhalations (DIs) and with 5 DIs taken after each MCh dose. Flow was measured on partial expiratory flow-volume curves at an absolute lung volume (plethysmographically determined) equal to 25% of control forced vital capacity (FVC). Airway inflammation was assessed in asthmatic subjects by analysis of induced sputum. Even when DIs were prohibited, the dose of MCh causing a 50% decrease in forced partial flow at 25% of control FVC (PD(50)MCh) was lower in asthmatic than in healthy subjects (P < 0.0001). In healthy but not in asthmatic subjects, repeated DIs significantly decreased the maximum response to MCh [from 90 +/- 4 to 62 +/- 8 (SD) % of control, P < 0.001], increased PD(50)MCh (P < 0.005), without affecting the dose causing 50% of maximal response. In asthmatic subjects, neither PD(50)MCh when DIs were prohibited nor changes in PD(50)MCh induced by DIs were significantly correlated with inflammatory cell numbers or percentages in sputum. We conclude that 1) even when DIs are prohibited, the responsiveness to MCh is greater in asthmatic than in healthy subjects; 2) repeated DIs reduce airway responsiveness in healthy but not in asthmatic subjects; and 3) neither airway hyperresponsiveness nor the inability of DIs to relax constricted airways in asthmatic subjects is related to the presence of inflammatory cells in the airways

Reviving Metapersonal Charisma in Max Weber

More than a century after Max Weber’s Vocation Lectures, the idea of charisma is still commonly associated with a leader’s personal qualities. This personalistic and—as I argue—simplistic understanding of the Weberian theory of charisma was perpetuated, especially in leadership studies, during the twentieth century by political scientists, social psychologists, and sociologists. Generally overlooked is the fact that the Weberian notion of charisma comprises diverse and fundamental metapersonal meanings that transcend individual qualities and revolve, among other things, around a specific combination of public positions, temporal contexts, and collective expectations. After framing the ambivalence of the concept of charisma within more fundamental and fertile ambivalences of Max Weber’s epistemological approach, this article demonstrates that metapersonal understandings of charisma actually prevailed in Weber’s writings prior to his late—and pedagogical—Vocation Lectures and series of newspaper articles. In the final part, I deduce from Weber’s writings a repertoire of metapersonal forms of charisma in politics, and I conclude that, when contemporary political leaders seek to activate such charismatic processes in order to pursue essentially charismatic forms of legitimation, important implications can arise regarding the unstable balance among liberal democracies, populisms, and authoritarianisms

Pulmonary fibrosis and lung carcinogenesis: do myofibroblasts and cancer-associated fibroblasts share a common identity?

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Pneumomediastinum after transbronchial cryobiopsy

Pneumomediastinum is defined as the presence of air or gas within the mediastinum and it rarely complicates bronchoscopy. We report, to our best knowledge, the first case of pneumomediastinum following a transbronchial cryobiopsy (TBLC). TBLC is considered a safe procedure as compared with both transbronchial biopsy and surgical lung biopsy. Systematic reviews, metanalysis and a Pubmed research, revealed that in literature no pneumomediastinum has been mentioned after TBLC. We report this case for to make it known to interventional pulmonologists the possibility that a pneumomediastinum can follow a TBLC. In our case the spontaneous resolution in few days did not require any intervention

Competence in transbronchial cryobiopsy

Over the last decade transbronchial lung cryobiopsy (TBLC) has proven to be an “innovative application” of an “old procedure” for the histologic diagnosis of diffuse interstitial lung diseases (DI LDs). Thus, the technique of TBL cryobiopsy is now adopted for diagnostic purposes, transbronchially in peripheral airways to sample lung parenchyma, whereas this same technique was traditionally employed in the past for therapeutic purposes, essentially for the management of malignant obstruction of central airways. When patients with interstitial lung diseases (ILDs) need histopathological data in their diagnostic pathway, this bioptic approach could be a valid alternative to surgical lung biopsy, that is still the gold standard at the moment. TBL cryobiopsy has a good safety profile, its sensitivity and specificity appear good overall in idiopathic pulmonary fibrosis. In the last ten years, many papers have been published about this procedure defining modalities by which cryobiopsy should be performed. These studies have shown that TBL cryobiopsy is feasible, it allows to obtain larger lung parenchymal specimens (3 times larger than “classic” transbronchial biopsies), characterized by unaltered and artefact-free morphology, and it represents a safe and poorly invasive diagnostic tool for the histologic diagnosis of ILDs. The technical aspects are really important, and they still need a complete standardization. TBL cryobiopsy should be part of an equipment of the modern interventional pulmonologist, who should know indications and contraindications of this methodic and the technical aspects of the procedure. This is a complex procedure requiring to be performed by endoscopists working in specialized centers with specific knowledge of DILDs, and a multidisciplinary approach, which represent pre-requisites for admission to training in this procedure

A novel digital twin for battery energy storage systems in micro-grids

Nowadays, traditional power grids, conventionally designed with a centralized paradigm, are evolving toward more decentralized configurations with numerous smaller nodes (prosumers), leading to increased interactions and complexity. In this context, digital twins (DTs) come in handy to replicate the behavior of a physical process in a fast, virtual, and safe way. This paper introduces a novel DT of a battery energy storage system (BESS), designed as a general-purpose framework adaptable for employment in complex scenarios. In addition to the DT design, this work presents a practical implementation of the proposed framework, rigorously validated through an extensive experimental campaign using real-world data. Specifically, the model is tested on realistic datasets, including a photovoltaic (PV) power profile, an experimental microgrid setup, and aged battery data. The results demonstrate the DT’s strong emulation capabilities, with a Mean Absolute Percentage Error (MAPE) consistently below 0.50% across all experiments