Notes on Giant Gravitons on PP-waves

We investigate the giant gravitons in the maximally supersymmetric IIB pp-wave from several viewpoints: (i) the dynamics of D3-branes, (ii) the world-sheet description and (iii) the correlation functions in the dual N=4 Yang-Mills theory. In particular, we derive the BPS equation of a D3-brane with magnetic flux, which is equivalent to multiple D-strings, and discuss the behavior of solutions in the presence of RR-flux. We find solutions which represent the excitations of the giant gravitons in that system.Comment: 25 pages, Latex, typos corrected, (minor) factors in eq.(2.11),(2.12),(2.16),(2.17) corrected, a footnote added, to appear in JHE

Nernst Effect in Electron-Doped Pr2−x_{2-x}Cex_{x}CuO4_4

The Nernst effect of Pr$_{2-x}$Ce$_{x}$CuO$_4$ (x=0.13, 0.15, and 0.17) has been measured on thin film samples between 5-120 K and 0-14 T. In comparison to recent measurements on hole-doped cuprates that showed an anomalously large Nernst effect above the resistive T$_c$ and H$_{c2}$ \cite{xu,wang1,wang2,capan}, we find a normal Nernst effect above T$_c$ and H$_{c2}$ for all dopings. The lack of an anomalous Nernst effect in the electron-doped compounds supports the models that explain this effect in terms of amplitude and phase fluctuations in the hole-doped cuprates. In addition, the H$_{c2}$(T) determined from the Nernst effect shows a conventional behavior for all dopings. The energy gap determined from H$_{c2}$(0) decreases as the system goes from under-doping to over-dopingin agreement with the recent tunnelling experiments

Physical properties of FeSe0.5_{0.5}Te0.5_{0.5} single crystals grown under different conditions

We report on structural, magnetic, conductivity, and thermodynamic studies of FeSe$_{0.5}$Te$_{0.5}$ single crystals grown by self-flux and Bridgman methods. The samples were prepared from starting materials of different purity at various temperatures and cooling rates. The lowest values of the susceptibility in the normal state, the highest transition temperature $T_c$ of 14.5 K, and the largest heat-capacity anomaly at $T_c$ were obtained for pure (oxygen-free) samples. The critical current density $j_c$ of $8 \times 10^4$ A/cm$^2$ (at 2 K) achieved in pure samples is attributed to intrinsic inhomogeneity due to disorder at the cation and anion sites. The impure samples show increased $j_c$ up to $2.3 \times 10^5$ A/cm$^2$ due to additional pinning centers of Fe$_3$O$_4$. The upper critical field $H_{c2}$ of $\sim 500$ kOe is estimated from the resistivity study in magnetic fields parallel to the \emph{c}-axis. The anisotropy of the upper critical field $\gamma_{H_{c2}} = H_{_{c2}}^{ab}/H_{_{c2}}^{c}$ reaches a value $\sim 6$ at $T\longrightarrow T_c$. Extremely low values of the residual Sommerfeld coefficient for pure samples indicate a high volume fraction of the superconducting phase (up to 97%). The electronic contribution to the specific heat in the superconducting state is well described within a single-band BCS model with a temperature dependent gap $\Delta_0 = 27(1)$ K. A broad cusp-like anomaly in the electronic specific heat of samples with suppressed bulk superconductivity is ascribed to a splitting of the ground state of the interstitial Fe$^{2+}$ ions. This contribution is fully suppressed in the ordered state in samples with bulk superconductivity.Comment: 11 pages, 11 figures, 3 table

Integrated motor drives: state of the art and future trends

With increased need for high power density, high efficiency and high temperature capabilities in Aerospace and Automotive applications, Integrated Motor Drives (IMD) offers a potential solution. However, close physical integration of the converter and the machine may also lead to an increase in components temperature. This requires careful mechanical, structural and thermal analysis; and design of the IMD system. This paper reviews existing IMD technologies and their thermal effects on the IMD system. The effects of the power electronics (PE) position on the IMD system and its respective thermal management concepts are also investigated. The challenges faced in designing and manufacturing of an IMD along with the mechanical and structural impacts of close physical integration is also discussed and potential solutions are provided. Potential converter topologies for an IMD like the Matrix converter, 2-level Bridge, 3-level NPC and Multiphase full bridge converters are also reviewed. Wide band gap devices like SiC and GaN and their packaging in power modules for IMDs are also discussed. Power modules components and packaging technologies are also presented

Nuclear-cytoplasmic translocation of MCIDAS couples transcription with massive de novo centriole biogenesis in multiciliated cells

Multiciliated cells (MCCs) bear numerous motile cilia that drive fluid flow, but how numerous centrioles for multiciliation are generated has remained unresolved. Here, we report that the “master” MCC transcriptional regulator, MCIDAS, moonlights in the cytoplasm to organize massive centriole biogenesis. Like MCIDAS, its co-transcriptional factors, E2F4 and E2F5, also undergo cytoplasmic accumulation, colocalizing with MCIDAS and forming procentrioles. MCIDAS loss inhibited E2F4/5 cytoplasmic accumulation and blocked centriole assembly. Furthermore, we show that the cytoplasmic accumulation of MCIDAS is mediated by CRM1-dependant nuclear export, and its inhibition specifically compromised centriole biogenesis. By contrast, on loss of parental centrioles and deuterosomes, which does not impair centriole formation, E2F4 cytoplasmic localization remained unaffected, establishing that the MCIDAS-E2F4/5 cytoplasmic complex represents the de novo centriole biogenesis pathway. We have also assembled a comprehensive list of MCIDAS targets, a resource which will enable further exposition of MCC biology and pathological mechanisms of motile ciliopathies

Asymmetries in the production of lambda zero, cascade minus, and omega minus hyperons in 500 GeV/c pi minus-Nucleon Interactions

Using data from Fermilab fixed-target experiment E791, we have measured particle-antiparticle production asymmetries for lambda zero, cascade minus, and omega minus hyperons in pi minus-nucleon interactions at 500 GeV/c. The asymmetries are measured as functions of Feynman-x (x_F) and pt^2 over the ranges of -0.12 GE x_F LE 0.12 and 0 GE pt^2 LE 4 (GeV/c)^2. We find substantial asymmetries, even at x_F = 0. We also observe leading-particle- type asymmetries which qualitatively agree with theoretical predictions.Comment: 15 pages, including 5 figures and 2 tables. To be submitted to Phys. Lett.

Track A Basic Science

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138319/1/jia218438.pd

Track D Social Science, Human Rights and Political Science

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138414/1/jia218442.pd

New insights into the genetic etiology of Alzheimer's disease and related dementias

Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/'proxy' AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele