117 research outputs found

    TWITTER STATISTICS EMOTION EVALUATION EVALUATION OF DEEP LEARNING METHODS

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    This analysis compares and contrasts a variety of methods for assessing emotions in Twitter data. Deep learning (DL) methods have gained momentum in this field among academics, who collaborate on a level playing field to tackle a wide variety of problems. CNNs, which are used to locate pictures, and recurrent neural networks (RNNs), which may be utilized successfully in natural language processing (NLP), are two types of neural networks. For this reason, two types of neural networks are explicitly utilized. These images are used to assess and compare CNN ensembles and variants, as well as RNN category networks with long-term memory (LSTM). We also associate clothing with the type phrase embedding structures Word2Vec and the global phrase representation vectors (Glove). To put these methods to the test, we utilized information from the Seminal (Seminal), one of the most well-known international workshops on the internet. Different trials and combinations are used, and the better results for each variation are linked to their average efficiency. This study adds to the area of sentiment analysis by assessing the outcomes, benefits, and drawbacks of various methods using an evaluation method that use a single testing system for the same dataset and machine configuration

    DESIGN, IN-SILICO DOCKING AND PREDICTIVE ADME PROPERTIES OF NOVEL PYRAZOLINE DERIVATIVES WITH SELECTIVE HUMAN MAO INHIBITORY ACTIVITY

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    Objectives: Curcumin, a known hMAO-A (human Monoamine oxidase-A) inhibitor from Curcuma longa has never been recognized for this property due to its poor permeability and extensive metabolism. Thus, the main objective of this study is to incorporate structural features of Curcumin in the pyrazoline scaffold as an attempt to get potent, selective hMAO-isoform inhibitors with improved permeability.Methods: A series of twelve novel 4, 4'-(4, 5-dihydro-1H-pyrazole-3,5-diyl)bis(2-methoxyphenol) derivatives (1-12) were designed based on the structure of Curcumin. All the designed compounds were evaluated for their hMAO inhibitory activity by in-silico docking studies (Autodock4.20). The both isomers (R-and S-isomer) are considered for simulation approach to understand the effect of chirality and other structural features that determine the potency and selectivity. In order to judge the pharmacokinetic behavior, all the derivatives were evaluated for their in-silico ADME properties by using Qik Prop v 3.0.Results: The results of the present study showed that all the designed compounds were found to be potent and selective hMAO-isoform inhibitors, and exhibited lead like properties from the calculated ADME parameters. Curcumin was taken as a standard for comparison to judge any improvement in permeability.Conclusion: The design strategy adopted has predicted improved potency, selective towards hMAO-isoform and permeability characteristics in comparison with Curcumin.Â

    Uniqueness Based Records Out Cause With Complete Audit In The Clouds

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    CRA must retain an arbitrary confidential value for users without affecting the security of the revocable IBE plan. In the Search Engine Optimization and Elmira Plan, for each user, each user creates a secret key by hitting some partial keys, which depend on the partial keys that grandparents use in the hierarchy tree. Another drawback is the lack of scalability, which means that the KU-CSP should have a secret value for each user. In this article, we recommend a new, revocable IBE plan with Cloud Revocation Authority to address each of the shortcomings, i.e. the performance is greatly improved and the CRA maintains system confidentiality for users only. Finally, we expanded the proposed IBE revocable plan to provide a CRA-supported certification plan for a limited time period to manage multiple cloud services. In the current system, bad-behaved users / at-risk in ID-PKS configuration are naturally high. The immediate cancellation method employs a reliable web-authorizing authority to reduce the burden of PKG management and help users decode the encrypted text. For experimental results and reward analysis, our plan is perfect for mobile devices. For security analysis, we make it clear that our plan is completely safe against adaptive recognition attacks according to Daffier-Hellman's two-pronged assumption. Outlines define the structure of an IBE cancellable plan with CRA and define their own security concepts to design potential threats and attacks. CRA Assisted Authentication Plan with Limited Time Rights to Manage Multiple Cloud Services

    STRUCTURAL AND THERMAL ANALYSIS OF VARIED METAL WELDING OF 1020 MILD METAL AND 304 STAINLESS STEEL

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    Joining of distinct metals has observed its use broadly in energy new release, electronic, nuclear reactors,petrochemical and chemical industries mostly to get tailor-made homes in a factor and reduction in weight. However efficient welding of distinctive metals has posed a major challenge due to difference in thermo-mechanical and chemical residences of the materials to be joined underneath a common welding situation. This factors a steep gradient of the thermo-mechanical houses alongside the weld. A kind of issues come up in distinctive welding like cracking, massive weld residual stresses, migration of atoms throughout welding causing stress awareness on one facet of the weld, compressive and tensile thermal stresses, stress corrosion cracking, and so forth. Weld residual stress and thermal stress had been analyzed for assorted steel welding of 304 stainless-steel to 1020 mild steel taking 302 stainless steel because the filler metallic. Similarly taking pressure developed as an index the susceptibility of the welded joint to stress corrosion cracking had been studied. It is found that once the filler steel is replaced by Inconel 625 significant growth is obtained within the welded joint in terms of discount in stress developed and stress corrosion cracking. Also the concern of carbon migration is eliminated by way of Inconel 625 as a weld filler metal because of the resistance of nickel-founded alloys to any carbon diffusion through them

    Antecedents of Green Purchase Intention using the Theory of Planned Behavior Model: Evidence from India

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    The study’s purpose is to examine the effect of antecedents (green ads, green brand image, environmental knowledge, concern, and attitude) on green purchase intention using the theories of reasoned action and planned behavior, with subjective norms and perceived behavioral control acting as moderators. Snowball sampling was used to collect data from 323 Indian respondents, which was then analyzed using structural equation modelling. The findings show that green ads and brand image significantly impacted environmental knowledge, concern, and attitude. Similarly, environmental knowledge had a positive impact on environmental concern and green attitude but did not impact green purchase intention, whereas environmental concern had a favorable impact on green attitude but did not impact green purchase intention; attitude had a significant impact on green purchase intention. Moderation results revealed that subjective norms had a positive moderation relationship between attitude and green purchase intention. However, there was no moderate relationship between environmental knowledge, concern, and green purchase intention. In contrast, perceived behavioral control had a positive moderation relationship between environmental knowledge, concern, attitude, and green purchase intention

    Power Quality Improvement Features For A Distributed Generation System Using Grid Interface Inverter

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    This paper presents that, the renewable energy resources are being increasingly connected to distribution systems by utilizing power electronic converters. And it presents a novel control strategy for achieving maximum benefits from these grid-interfacing inverters when installed in 3-phase 4-wire distribution systems. It is controlled to perform as a multi-function device by incorporating active power filter functionality. The inverter can thus be utilized as: power converter to inject power generated from RES to the grid, and shunt APF to compensate current unbalance, load current harmonics, load reactive power demand and load neutral current. All of these functions may be accomplished either individually or simultaneously. With such a control, the combination of grid-interfacing inverter and the 3-phase 4-wire linear/non-linear unbalanced load at point of common coupling appears as balanced linear load to the grid

    Analysis of onset time and intubating conditions following intravenous administration of Rocuronium 0.6mg/kg and Rocuronium 0.9mg/kg doses and its comparison with Succinylcholine 1.5mg/kg for Rapid Sequence Induction

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    Background: The purpose of this study was to compare rocuronium to succinylcholine in adult patients undergoing elective surgery using two different doses of 0.6 mg/kg and 0.9 mg/kg for rapid sequence endotracheal intubation. Methodology: Total of 90 cases were randomly divided into three groups of 30 in each. Group S was intubated with 1.5 mg/kg body weight succinylcholine chloride, group R1 intubated with 0.6 mg/kg body weight rocuronium bromide, and group R2 was intubated with 0.9 mg/kg body weight rocuronium bromide. Results: 90% in group S, 53.33% in group R1, and 76.67% in group R2 cases had excellent intubating conditions. The onset time of group S was significantly shorter than that of group R2 and group R1 doses. There was statistical significance difference observed among group S, group R1, and group R2 regarding clinical onset of action (45.58±4.198, 56.38±5.032, and 52.59±3.966 seconds).  Group S, group R1, and group R2 had mean duration of action of 5.24±1.453, 23.96±2.14, and 43.18±2.12 minutes respectively. In group R1 and group R2, the mean heart rates were increased by 47.1% and 33.9%, and mean arterial pressure increased by 28.56% and 24.92% observed one min after intubation, and returned to preinduction levels after 5 minutes. In all three groups, no significant side effects were observed. Conclusion: Rocuronium at 0.9 mg/kg dose is preferable and alternative to succinylcholine in cases where succinylcholine is contraindicate

    In silico docking studies of Yucca gloriosa L. phytoconstituents with TNF-α, IL-6 and IL-13 receptor against Asthma

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    Yucca gloriosa L has been comprehensively assessed in vitro and in vivo for its action against asthma Y gloriosa L is a rich source of phenolic compounds such as gloriosaols A E and yuccaols A E which exhibit potent antioxidant activity Gloriosaols A E and yuccaols A E are structurally related to corticosteroids The current study describes the in silico docking of some important anti asthmatic phytoconstituents from the plant Y gloriosa L with molecular targets of asthma Toward the recognition of the binding methods of these pharmacologically dynamic components molecular modelling studies were carried out with target proteins i e interleukin IL 6 1N26 IL 13 3LB6 and TNF 2AZ5 using in silico molecular docking The components demonstrated encouraging binding interactions with the amino acid residues at the active sites of these proteins authenticating their verified efficiency as anti asthmatic agents The current research in addition provides insight into the possible herbal drug receptor interaction and synthetic drug montelukast sodium receptor interaction for the possible management of asthma ScienceIn Publishing ISSN 2347 982
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