La grossesse chez les hémodialysées chroniques

La survenue d'une grossesse en hémodialyse chronique (HDC) est rare, mais depuis la description du premier cas par Confortini en 1971, plusieursobservations ont été rapportées. L'hémodialyse a considérablement  amélioré la fertilité de ces patientes. Nous rapportons l'expérience de  douze grossesses survenues entre 1999 et 2014, chez douze patientes d'âge médian 34 ans (22-44), en hémodialyse (HD) depuis 40 mois  (3-72), l'âge gestationnel moyen de diagnostic est de 16 semaines  d'aménorrhée, la grossesse était compliquée dans 50% des cas par un hydramnios. Le terme moyen est de 35 semaine d'aménorrhée (SA) et l'accouchement a été réalisé dans 90% des grossesses par voie basse. Le poids moyen des nouveau-nés est de 1800g. De telles grossesses sont à haut risque du fait de la fréquence des complications. Elles devraient être contrôlées par les équipes multidisciplinaires, et la consultation prénatal ne devrait pas être négligée. L'objectif de ce travail est de rapporter notre expérience concernant la survenue d'une grossesse chez les patientes dialysées et de la confronter aux données de la littérature

Profil des insuffisants rénaux chroniques diabétiques à l’initiation de l’hémodialyse au service de néphrologie et dialyse de l’hôpital militaire de Rabat, Maroc

Le diabète constitue une cause fréquente d'insuffisance rénale chronique terminale (IRCT) dans le monde. Ce travail présente une étude clinique rétrospective dont le but est de décrire le profil clinico-biologique des patients diabétiques en IRCT, de le comparer aux patients non-diabétiques au stade d'IRCT, et de suivre l'évolution de leurs abords vasculaires, afin d'en déduire des conclusions sur une prise en charge particulière des patients diabétiques. Les paramètres cliniques et biologiques concernant les patients mis en hémodialyse dans notre formation entre le 01 janvier 2006 et le 31 décembre 2011, ont été recueilli et analysés. Nous avons procédé à l'étude comparative des patients en fonction de l'existence ou non d'une néphropathie diabétique, et nous nous sommes intéressés à l'évolution de leurs abords vasculaires. Il s'agit de 207 patients insuffisants rénaux chroniques, dont 86 diabétiques. Le groupe des patients diabétiques était moins suivi avant la mise en hémodialyse (3,66 mois vs. 6,32 mois), avec une prise beaucoup plus importante d'antihypertenseurs (1,87 vs. 1,14, p<0,001). L'échec des abords vasculaires était plus important chez les patients diabétiques (45% vs. 27%, p=0,006), avec une survie moyenne plus faible de leurs abords vasculaires (509 vs 753 jours, p=0,003). L'étude comparative des taux d'hémoglobine, de parathormone intacte, d'albuminémie et de C-réactive protéine, entre le groupe de patients diabétiques et non diabétiques était non significative. Notre étude soulève le problème du suivi néphrologique chez les diabétiques, pourtant censés être mieux suivis, et son retentissement sur l'avenir de leurs abords vasculaires.Key words: Diabète, insuffisance rénale chronique, hémodialys

Ruminal solubility and bioavailability of trace minerals in growing lambs fed varying levels of live yeast with a total mixed ration

IntroductionThis study evaluated the effects of yeast supplementation (YS) on trace mineral (TM) concentrations in blood serum, rumen fluid, and meat, as well as on the growth performance of lambs fed a total mixed ration (TMR). In addition, correlations among TM concentrations in different tissues were examined.MethodsA total of 24 healthy, growing lambs were randomly assigned to three groups (n = 8/group): YS0.00, YS1.50, and YS3.00 (0.00, 1.50, and 3.00 g yeast/lamb/day). Feed intake and body weight were monitored every four weeks during the 8-week trial. The samples of blood serum, rumen fluid, and meat were analyzed for Fe, Cu, Zn, I, Se, and Co using ICP-OES.Results and discussionIn the YS3.00 group, yeast supplementation significantly increased overall roughage intake. However, it decreased feed efficiency, indicating that although animals consumed more, nutrient utilization efficiency was altered. The YS1.50 group showed significantly higher serum levels of Mn, Cu, and Se (p < 0.05). Rumen fluid TM concentrations were significantly affected by treatment, with lower values observed in the YS1.50 and YS3.00 groups compared to the YS0.00 group. A similar pattern was observed in meat, with the YS1.50 group showing significantly higher levels of most TMs, except for I and Cu. Strong positive correlations (p < 0.05) were found between rumen and meat TM concentrations for Mn, Fe, Se, and I, as well as between rumen fluid and serum for Fe and Cu. In conclusion, yeast supplementation at 1.50 g/day increased trace mineral concentrations in serum and meat, with the exception of I and Cu, and improved correlations between rumen fluid and meat for Mn, Fe, Se, and I, as well as between rumen fluid and serum, in the growing lambs

Fourier Transform Infrared Spectroscopy as a Tool to Study Milk Composition Changes in Dairy Cows Attributed to Housing Modifications to Improve Animal Welfare

Animal welfare status is assessed today through visual evaluations requiring an on-farm visit. A convenient alternative would be to detect cow welfare status directly in milk samples, already routinely collected for milk recording. The objective of this study was to propose a novel approach to demonstrate that Fourier transform infrared (FTIR) spectroscopy can detect changes in milk composition related to cows subjected to movement restriction at the tie stall with four tie-rail configurations varying in height and position (TR1, TR2, TR3 and TR4). Milk mid-infrared spectra were collected on weekly basis. Long-term average spectra were calculated for each cow using spectra collected in weeks 8–10 of treatment. Principal component analysis was applied to spectral averages and the scores of principal components (PCs) were tested for treatment effect by mixed modelling. PC7 revealed a significant treatment effect (p = 0.01), particularly for TR3 (configuration with restricted movement) vs. TR1 (recommended configuration) (p = 0.03). The loading spectrum of PC7 revealed high loadings at wavenumbers that could be assigned to biomarkers related to negative energy balance, such as β-hydroxybutyrate, citrate and acetone. This observation suggests that TR3 might have been restrictive for cows to access feed. Milk FTIR spectroscopy showed promising results in detecting welfare status and housing conditions in dairy cows.</jats:p

Fourier Transform Infrared Spectroscopy as a Tool to Study Milk Composition Changes in Dairy Cows Attributed to Housing Modifications to Improve Animal Welfare

Animal welfare status is assessed today through visual evaluations requiring an on-farm visit. A convenient alternative would be to detect cow welfare status directly in milk samples, already routinely collected for milk recording. The objective of this study was to propose a novel approach to demonstrate that Fourier transform infrared (FTIR) spectroscopy can detect changes in milk composition related to cows subjected to movement restriction at the tie stall with four tie-rail configurations varying in height and position (TR1, TR2, TR3 and TR4). Milk mid-infrared spectra were collected on weekly basis. Long-term average spectra were calculated for each cow using spectra collected in weeks 8–10 of treatment. Principal component analysis was applied to spectral averages and the scores of principal components (PCs) were tested for treatment effect by mixed modelling. PC7 revealed a significant treatment effect (p = 0.01), particularly for TR3 (configuration with restricted movement) vs. TR1 (recommended configuration) (p = 0.03). The loading spectrum of PC7 revealed high loadings at wavenumbers that could be assigned to biomarkers related to negative energy balance, such as β-hydroxybutyrate, citrate and acetone. This observation suggests that TR3 might have been restrictive for cows to access feed. Milk FTIR spectroscopy showed promising results in detecting welfare status and housing conditions in dairy cows

Recent advances in CO2 adsorption using aerogel materials: A review

The rapidly increasing concentration of carbon dioxide (CO2) in the atmosphere, primarily due to industrial processes and fossil fuel combustion, presents a serious environmental challenge. As a potent greenhouse gas, CO2 contributes significantly to global warming and climate change, necessitating innovative solutions for its capture and sequestration. Numerous materials have been developed and employed for CO2 capture. Among these materials, aerogels have emerged as a promising class of adsorbents for effective CO2 capture. The synthesis of aerogels allows for tailored textural characteristics and surface chemistries, making them highly effective in capturing CO2. Innovations in aerogel technology have focused on enhancing their CO2 uptake capacity, selectivity, and stability under operational conditions. Although there are some existing reviews on CO2 capture using various materials, comprehensive evaluations focusing on aerogels for CO2 capture remain scarce in the literature. This highlights the novelty of this article and points out to the need for comprehensive reviews, as the one presented herein, to tackle recent progress, consolidate knowledge, and highlight gaps in this rapidly expanding field. Accordingly, this review article explores recent advances in the development and application of aerogel materials for CO2 capture, highlighting their potential to address this global issue. This article also systematically examines the modifications and optimizations of aerogels for improved performance, from the incorporation of amine functionalities to the development of composite and hybrid aerogel structures. Additionally, various aspects (i.e., adsorption mechanism, reactor configuration, techno-economic and life cycle analyses, and regeneration) of CO2 capture using aerogels are covered. Moreover, this review article identifies key areas for future research and development, emphasizing the need for continued innovation in material science to enhance the functionality and commercial viability of aerogels in CO2 capture applications. Accordingly, this review article offers detailed insights into aerogels as a vital solution to mitigate the adverse effects of increased atmospheric CO2

Diminishing Water-Intake may have Pragmatic Aspects in Lambs Fed on Pelleted Complete Diet and Reared under Thermo-Neutral Condition

Some basic questions regarding sheep’s ability to tolerate different levels of water intake (WI), especially when fed on a pelleted-complete diet (PCD) and reared under comfortable climatic conditions, are still open. To investigate the direct influence of different levels of WI in sheep fed PCD and reared under such conditions on the lambs' physiological (performance, thermal, blood and urine) status, 24 healthy male growing Najdi lambs were exposed under thermo-neutral conditions to three levels of WI (100%, 67%, and 33% of their ad libitum WI or water requirement) for 6 weeks. Meteorological, production performance, thermo-physiological, as well as blood and urine biochemical measurements, were all determined. The obtained findings clearly substantiate that reducing the level of water intake (p&lt;0.05) produced tangible effects in both 67-WI and 33-WI lamb groups. However, 67-WI lambs showed resilience to limited water availability by inducing proportional physiological responses in their production performances, body temperatures, blood metabolites, and renal function but within the homeostatic ranges similar (p&gt;0.05) to 100-WI lambs. Results collectively signify that diminishing WI up to 33% in lambs (fed on PCD and reared under comfortable conditions) would ensure that water is adequately conserved under prevailing water scarcity and can be implemented without compromising their homeostatic functions. Such applied approaches can consequently have a pragmatic aspect through improving water management approaches required for PCD-based sheep production under water scarcity conditions, which is crucial to economical animal production and responsible animal stewardship. Feasibility studies are thereby highly recommended