1-Methyl-3-(2-methyl­phen­yl)-3,3a,4,9b-tetra­hydro-1H-chromeno[4,3-c][1,2]oxazole-3a-carbonitrile

In the title compound, C19H18N2O2, the five-membered isoxazole ring adopts an envelope conformation and the deviation of the N atom from the mean plane of the isoxazole ring is −0.3256 (11) Å. The pyran ring adopts a half-chair conformation. The isoxazole ring forms dihedral angles of 44.07 (7) and 84.23 (7)° with the pyran and methyl­benzene rings, respectively. The mol­ecular structure is stabilized by weak C—H⋯π inter­actions

A new protocol for the syntheses of (E)-3-benzylidenechroman-4-ones: a simple synthesis of the methyl ether of bonducellin

Development of a simple new methodology for the synthesis of (E)-3-benzylidenechroman-4-ones using methyl 3-aryl- 3-hydroxy-2-methylenepropanoates, the Baylis-Hillman adducts derived from methyl acrylate, and the application of this methodology for the synthesis of the methyl ether of bonducellin, an important natural product, and 3-(4-methoxybenzylidene)- 6-methoxychroman-4-one, an antifungal agent, are described

Tandem construction of carbon-carbon and carbon-oxygen bonds in the Baylis-Hillman chemistry: synthesis of functionalized dl-bis-allyl ethers

Tandem coupling between acrylonitrile and aryl aldehydes under the catalytic influence of DABCO involving the construction of two carbon-carbon bonds and one carbon-oxygen bond leading to the synthesis of dl-functionalized bis-allyl ethers has been described

1-Methyl-3-(naphthalen-1-yl)-3,3a,4,9b-tetra­hydro-1H-chromeno[4,3-c]isoxazole-3a-carbonitrile

In the title compound, C22H18N2O2, the pyran ring of the chromene unit is fused with an isoxazole ring, which adopts an N-envelope conformation with the N atom lying 1.3291 (14) Å from the mean plane of the remaining ring atoms [maximum deviation = 0.341 (2) Å]. The dihedral angle between the isoxazole and chromene units is 43.74 (8)° and that between the iosxazole ring and the naphthalene ring system is 58.82 (8)°. In the crystal, the molecules are linked by weak C—H⋯π inter­actions

Methyl (Z)-2-[(4-bromo-2-formyl­phen­oxy)meth­yl]-3-(4-methyl­phen­yl)acrylate

In the title compound, C19H17BrO4, the dihedral angle between the two benzene rings is 82.9 (2)°. The mol­ecular structure is stabilized by an intra­molecular C—H⋯O hydrogen bond, which generates an S(7) ring motif. The crystal packing is stabilized by C—H⋯O hydrogen bonds, which generate two centrosymmetic ring systems with R22(18) and R22(14) graph-set motifs. The crystal packing is further stabilized by inter­molecular π–π inter­actions [centroid–centroid distance = 3.984 (2) Å]

(E)-2-(2-Formyl­phen­oxy­meth­yl)-3-phenyl­prop-2-ene­nitrile

In the title compound, C17H13NO2, the dihedral angle between the benzene and the phenyl ring is 65.92 (7)°. The carbonitrile side chain is almost linear, the C—C—N angle being 175.55 (14)°. The crystal structure is stabilized by inter­molecular C—H⋯O inter­actions

(E)-2-[(2-Formyl­phen­oxy)meth­yl]-3-(4-methyl­phen­yl)prop-2-ene­nitrile

In the title compound, C18H15NO2, the dihedral angle between the two benzene rings is 74.8 (1)°. The carbonitrile chain is almost linear, the C—C—N angle being 176.2 (2)°. In the crystal, π–π inter­actions [centroid–centroid distance = 3.842 (1) Å] are observed

(E)-6-Methyl-3-(2-methyl­benzyl­idene)­chroman-2-one

In the title compound, C18H16O2, the heterocyclic ring of the chroman-2-one system adopts a slightly distorted screw-boat conformation. The dihedral angle between the least-squares planes of the coumarin ring system and the benzene ring is 67.5 (1)°. The crystal packing features C—H⋯O hydrogen bonds, which link the mol­ecules into centrosymmetric R22(8) dimers, and C—H⋯π inter­actions

Methyl (2Z)-2-{[N-(2-formyl­phen­yl)-4-methyl­benzene­sulfonamido]­meth­yl}-3-(naphthalen-1-yl)prop-2-enoate

In the title compound, C29H25NO5S, the sulfonyl-bound benzene ring forms dihedral angles of 42.1 (1) and 48.5 (1)°, respectively, with the formyl-substituted benzene ring and the naphthalene residue. In the crystal, pairs of C—H⋯O inter­actions lead to the formation of R 2 2(10) inversion dimers, which are linked by further C—H⋯O inter­actions into supra­molecular tapes running along [100]. The crystal packing is further stabilized by C—H⋯π inter­actions