BRT Mesh Enrichment For VZG Using The Bead Device

Optimizing the BRT network is an immediate, arduous task to provide instant solutions to traditional cultures. This makes it important to devise quick ways to get answers to improve communication. BRT can be defined as "a high-quality bus system that facilitates rapid, comfortable and affordable transportation in the city by providing a variety of direct routes, expressways, efficient, and ideal for customers". . Bus Rapid Transit (BRT) is a popular choice for international transportation. The BRTS evaluation was performed by the BEAD tool and the current BRT network in Visakhapatnam was investigated to find potential network deficiencies. Road lines have been reconfigured and new stations introduced in order to increase space across the bus system. The communication system while travelling has been improved by introducing new methods and direct services. Waiting times for passenger transportation are reduced in many stations by changing service procedures to peak hours

Evaluation of the efficacy, safety and tolerability of Tacrolimus ointment in Indian patients of moderate to severe atopic dermatitis: A multicentric, open label, phase III study

AIM OF STUDY: Tacrolimus, a topical immunomodulator, has been introduced as a new treatment for moderate to severe atopic dermatitis. The present study was conducted to evaluate the efficacy, safety and tolerability of Tacrolimus ointment in patients of atopic dermatitis in an Indian setting. METHODS: The present study was a prospective, open, multicentric, Phase III trial.The duration of study was 5 weeks, including a 3-week active treatment period, preceded by a 1-week washout phase and followed by a 1-week follow-up phase. Patients diagnosed to be suffering from moderate to severe atopic dermatitis as per the Rajka and Langeland criteria were treated with Tacrolimus ointment 0.03% twice daily. Efficacy was assessed by modified Eczema Area Sensitivity Index (mEASI) score, patient's and physician's global assessment. Tolerability and safety was assessed by physical examination, laboratory parameters and evaluation of adverse events. RESULTS: There was a statistically significant decrease in the modified Eczema Area Sensitivity Index (mEASI) score (P<0.05). Patient's and Physician's global evaluation of treatment was complete resolution to very good improvement in most of the patients. The laboratory values were within normal limits. The drug was well tolerated. CONCLUSIONS: This study confirms the efficacy and safety of Tacrolimus ointment 0.03% in Indian patients of moderate to severe atopic dermatitis

Efficacy of pegylated interferon plus ribavirin in combination with corticosteroid for two cases of combined hepatitis C and autoimmune hepatitis

The treatment strategy for cases of combined autoimmune hepatitis (AIH) and chronic hepatitis C (CHC) has not yet been established. A 47-year-old woman and a 53-year-old-woman were hospitalized for treatment of CHC. Ultrasonography and histological findings revealed that their liver was not cirrhotic but did have chronic damage. The histological findings of both patients were suggestive of AIH. The patients were systematically treated with pegylated interferon-alpha 2b plus ribavirin which was preceded by and combined with corticosteroid (CS), and showed sustained virological responses and normal liver function. Although these two patients with combined AIH and CHC were successfully treated with this regimen, careful attention to exacerbation of hepatic inflammation is needed because hepatitis C viral load was increased due to immunosuppression during CS treatment

Primary mandibular tuberculous osteomyelitis mimicking ameloblastoma: A case report and literature review of mandibular tuberculous osteomyelitis

Primary Tuberculous osteomyelitis involving the mandible represents less than 2% of skeletal locations. In this paper, we report a case of mandibular tuberculosis detected after histopathological analysis of the surgically resected specimen during surgical management of a suspected case of ameloblastoma. A 14 -year-old male patient presented to us with history of right sided chin swelling. The clinical examination revealed a swelling, involving right body and parasymphysis of mandible, measuring approximately 6cm in length and 2cm in width, extending from right lateral incisor till the first molar. Radiological scans revealed a large multiloculated osteolytic expansive lesion measuring 52 x 20 x18 mm. Excision of the lesion was performed and reconstruction was done with iliac bone grafting. The histopathological findings revealed a granulomatous lesion, suggestive of tuberculous osteomyelitis. The patient was successfully treated with standard multidrug therapy. One year after completion of therapy, there were no signs of recurrence. Primary mandibular tuberculosis is an extremely rare entity. Its clinical presentation is not specific. Radiologically, tuberculosis has no characteristic appearance. The positive diagnosis is based on histology. Primary mandibular tuberculosis is rare and should be kept amongst differential diagnoses in susceptible population and in endemic areas

Production Of Bioethanol From Different Leaves Waste And Performance And Emission Characteristics Of Single Cylinder CI Engine

Abstract Background: The need of bioethanol is being increased nowadays; hence the production of bioethanol must be increased using cheaper and eco-friendly raw materials. Based on these criteria, different leaves wastes are considered as cheaper and eco-friendly. In the present study selected tree leaves wastes such as Rain tree, Jackfruit tree, Mango tree and Singapore cherry tree leaves waste were used as raw materials to produce bioethanol by using Saccharomyces cerevisiae (yeast). The operating conditions are pH 6.5, temperature 27±2°C, speed 80rpm, fermentation period 10 days. Also an attempt has been made to find out the suitability of extracted bioethanol as a fuel in CI engine. Results: Experimental work on performance and emission characteristics of ethanol blended diesel fuel was conducted on single cylinder four stroke CI engines at operating pressure 210 bar. The results obtained from this work shows that the higher rate of ethanol can be produced through fermentation of wet Jackfruit tree leaves, which gives good percentage of ethanol as compared to other tree leaves wastes. Conclusions: The conversion of waste into fuel, which forms an attractive solution towards both waste management and Biofuels generation.This study concludes that the Jackfruit tree leaves contain rich fermentable sugar can be converted into useful products like bioethanol that can serve as an alternative energy source.</jats:p

Comparison of the effects of parecoxib and diclofenac in preemptive analgesia: A prospective, randomized, assessor-blind, single-dose, parallel-group study in patients undergoing elective general surgery

BACKGROUND: Preoperative administration of analgesics may prevent or reducehyperalgesia, inhibit inflammation, and reduce pain by reducing the synthesis of prostaglandins in response to tissue damage caused by surgery. Nonsteroidal anti-inflammatory drugs (NSAIDs) are a potent, widely used class of analgesic agents; however, they may not be as effective as selective cyclooxygenase (COX)-2 inhibitors. OBJECTIVE: The aim of this study was to compare the efficacy and tolerabilityof the COX-2 inhibitor parecoxib sodium and the NSAID diclofenac sodium as preemptive analgesics in patients undergoing elective general surgery. METHODS: This was a prospective, randomized, assessor-blind, single-dose,parallel-group, comparative trial. Patients aged 18 to 65 years undergoing elective general surgery were enrolled. A single IM injection of parecoxib 40 mg or diclofenac 75 mg was administered 30 to 45 minutes before the induction of anesthesia. Surgery was performed as per standard protocol. The primary measures of efficacy were pain intensity score (measured on a visual analog scale [VAS]), pain relief score, duration of analgesia, and platelet aggregation response to adenosine diphosphate. Tolerability assessment included monitoring of treatment-emergent adverse events (AEs), physical examination, laboratory analysis, electrocardiography, and chest radiography. RESULTS: Eighty patients (56 men, 24 women; mean [SD] age, 45.96 [12.83] years) were enrolled in the study (40 patients per treatment group). All patients completed the trial. No pain was reported by any patient in the parecoxib group up to 12 hours; in the diclofenac group, no pain was reported up to 6 hours. At 12 hours, the mean (SD) VAS score was 2.33 (1.39) (moderate pain) in the diclofenac group and 0 (no pain) in the parecoxib group (P < 0.05). At 12 hours, total pain relief was reported by all 40 patients (100.0%) in the parecoxib group but by none (0.0%) in the diclofenac group, and 2 patients in the diclofenac group (5.0%) reported good pain relief (between-group difference for total + good pain relief, P < 0.05). Mean (SD) duration of analgesia was significantly longer in the parecoxib group than in the diclofenac group (19.48 [5.61] hours vs 8.32 [4.11 ] hours; P < 0.05). Platelet aggregation was significantly inhibited in the diclofenac group (change from baseline, 64.0%) but not in the parecoxib group (change from baseline, 12.0%) (P < 0.05). Both regimens were well tolerated, and no AEs were reported. CONCLUSIONS: In this study of patients undergoing elective general surgery,patients treated with the COX-2 specific inhibitor parecoxib experienced no pain at 12 hours, and the treatment was well tolerated. The results of this study suggest that good postoperative analgesia and minimal interference with platelet function may make parecoxib an alternative to the nonselective NSAID diclofenac in providing preemptive analgesia in patients undergoing general surgery

Real Time Implementation of Video Compression Based on DWT

In this paper highly efficient 3D Discrete Wavelet Transform architecture is designed and implemented on seven series FPGA. The throughput is analyzed and its performance matrices are compared with different video file format. Today top of the line high-end image and video consume huge amount of memory. The designed architecture of DWT based video compression is again executed in parallel processing mode and its execution time is tabulated demonstrates reduced the processing or execution time. This paper demonstrates the superiority of the designed architecture both in normal mode of execution and parallel processing mode of execution .We know that higher the throughput of the video processing design results in Low power consumption. The Internal Architecture of the design is explained in brief and is synthesized in Xilinx Vivado 17.4 and implemented on Zed board. Based on the experimental results of the design being implemented on FPGA, demonstrates the memory saving capabilities and superiority of this architecture. The resultant architecture has drastically reduced latency and has enhanced the speed of operation.</jats:p