The Relationship of Psychological Hardiness with Work Holism

Background and Aim: Present research intends to investigate relationship of psychological hardiness with work holism among high school teachers. Methods: The under study society includes all male and female high school teacher in Ghorveh city in the academic year 2012-2013. Using simple random sampling method, a sample size of 100 male and female teachers was selected. To collect data, Kobassa Psychological Hardiness Questionnaire and Aghabeigi Workaholics Questionnaire were employed. To analyze the data, descriptive statistics (frequency, percentage, mean and standard deviation) and inferential statistics (t-test and regression analysis) were used. Results: The findings indicated that there is negative and significant relationship between the variables psychological hardiness and work holism. In addition, there is association between gender and psychological hardiness and between gender and work holism, also the constituents of psychological hardiness (commitment, control and challenge) are able to predict work holism

Interaction of viral oncogenic proteins with the Wnt signaling pathway

It is estimated that up to 20% of all types of human cancers worldwide are attributed to viruses. The genome of oncogenic viruses carries genes that have protein products that act as oncoproteins in cell proliferation and transformation. The modulation of cell cycle control mechanisms, cellular regulatory and signaling pathways by oncogenic viruses, plays an important role in viral carcinogenesis. Different signaling pathways play a part in the carcinogenesis that occurs in a cell. Among these pathways, the Wnt signaling pathway plays a predominant role in carcinogenesis and is known as a central cellular pathway in the development of tumors. There are three Wnt signaling pathways that are well identified, including the canonical or Wnt/β-catenin dependent pathway, the noncanonical or β-catenin-independent planar cell polarity (PCP) pathway, and the noncanonical Wnt/Ca2+ pathway. Most of the oncogenic viruses modulate the canonical Wnt signaling pathway. This review discusses the interaction between proteins of several human oncogenic viruses with the Wnt signaling pathway

Development and Validation of an Intervention Protocol based on the Mental Security of Divorced Women on Resilience and Psychological Well-being: Intervention Protocol based on the Mental Security of Divorced Women

Background and Aim: The research was conducted with the aim of developing and validating an intervention protocol based on the mental security of divorced women and investigating its effectiveness on their resilience and psychological well-being. Materials and Methods: The research was conducted using a mixed method. The research method in the quantitative part was a quasi-experiment with a pre-test-post-test design with a control group. The statistical population of this part of the research consisted of all the divorced women of al-Shatar city in 1400-1401, and 30 people (15 people in the experimental group and 15 people in the control group) were selected by simple random method. For each investigated factor, considering 12 experts, the minimum acceptable value for CVR is 0.88 and for CVI index is 0.79 based on Lauche table. In the qualitative part, a semi-structured interview and the tools used in the quantitative part were the Connor Davidson Resilience Scale Questionnaire (CD-RIS), and the psychological well-being questionnaire of Rief (1998).  Results: In the quantitative part, the results showed that the intervention protocol based on the psychological security of divorced women is effective on resilience and psychological well-being of divorced women. Conclusion: Several factors play a role in the process of forming the mental security of divorced women, and by identifying them in different environments, cultures, and societies, necessary and effective measures can be taken to improve and promote the mental security of divorced women