Mapping of risk prone areas of kala-azar (Visceral leishmaniasis) in parts of Bihar state, India: An RS and GIS approach

Background & objectives: The kala-azar fever (Visceral leishmaniasis) is continuing unabated in India for over a century, now being largely confined to the eastern part of India mainly in Bihar state and to some extent in its bordering states like West Bengal and Uttar Pradesh. Two study sites namely Patepur block in Vaishali district with high endemicity in northern part and Lohardagga block in Lohardagga district with absolute non-endemicity in southern part of Bihar were selected for the study with the following objectives : (i) to study the macro-ecosystem in relation to distribution of vector -Phlebotomus argentipes; (ii) to identify/map the risk prone areas or villages in a block for quick remedial measures; and (iii) to make use of satellite remote sensing and GIS to demonstrate the utility for rapid assessment of landuse/landcover and their relation with the incidence of kala-azar leading to the mapping of risk prone areas. Methods: Indian Remote Sensing (IRS)-1D LISS III satellite data for the periods of March and November 2000 were analysed in Silicon graphic image processing system using ERDAS software. False color composites (FCC) were generated and landuse/landcover was assessed using Maximum likelihood supervised classification techniques based on ground truth training sets. During the study the GIS functions are used to quantify the remotely sensed landscape proportions of 5 km 2 buffer surrounding each known group of villages of high occurrence of sandflies in endemic and non-endemic study sites. Instead of traditional ground based survey methods to vector surveillance, the present study used a combination of remote sensing (RS) and geographical information system (GIS) approach to develop landscape predictors of sandfly abundance-an indicator of human vector contact and as a measure of risk prone areas. Results: Statistical analysis using the remotely sensed landscape variables showed that rural villages surrounded by higher proportion of transitional swamps with soft stemmed edible plants and banana, sugarcane plantations had higher sandfly abundance and would, therefore, be at higher risk prone areas for man-vector contact. Interpretation & conclusion: The present study clearly brought out the usefulness of satellite remote sensing technology in generating the crucial information on spatial distribution of landuse/landcover classes with special emphasis on indicator landcover classes thereby helping in prioritising the area to identify risk prone areas of kala-azar through GIS application tools

Mapping of risk prone areas of kala-azar (Visceral leishmaniasis) in parts of Bihar state, India: an RS and GIS approach

Background & objectives: The kala-azar fever (Visceral leishmaniasis) is continuing unabated inIndia for over a century, now being largely confined to the eastern part of India mainly in Bihar stateand to some extent in its bordering states like West Bengal and Uttar Pradesh. Two study sites namelyPatepur block in Vaishali district with high endemicity in northern part and Lohardagga block inLohardagga district with absolute non-endemicity in southern part of Bihar were selected for thestudy with the following objectives : (i) to study the macro-ecosystem in relation to distribution ofvector —Phlebotomus argentipes; (ii) to identify/map the risk prone areas or villages in a block forquick remedial measures; and (iii) to make use of satellite remote sensing and GIS to demonstratethe utility for rapid assessment of landuse/landcover and their relation with the incidence of kalaazarleading to the mapping of risk prone areas.Methods: Indian Remote Sensing (IRS)-1D LISS III satellite data for the periods of March andNovember 2000 were analysed in Silicon graphic image processing system using ERDAS software.False color composites (FCC) were generated and landuse/landcover was assessed using Maximumlikelihood supervised classification techniques based on ground truth training sets. During the studythe GIS functions are used to quantify the remotely sensed landscape proportions of 5 km2 buffersurrounding each known group of villages of high occurrence of sandflies in endemic and nonendemicstudy sites. Instead of traditional ground based survey methods to vector surveillance, thepresent study used a combination of remote sensing (RS) and geographical information system (GIS)approach to develop landscape predictors of sandfly abundance—an indicator of human vector contactand as a measure of risk prone areas.Results: Statistical analysis using the remotely sensed landscape variables showed that rural villagessurrounded by higher proportion of transitional swamps with soft stemmed edible plants and banana,sugarcane plantations had higher sandfly abundance and would, therefore, be at higher risk proneareas for man-vector contact.Interpretation & conclusion: The present study clearly brought out the usefulness of satellite remotesensing technology in generating the crucial information on spatial distribution of landuse/landcoverclasses with special emphasis on indicator landcover classes thereby helping in prioritising the areato identify risk prone areas of kala-azar through GIS application tools

The TIGRE gamma-ray telescope

TIGRE is an advanced telescope for gamma-ray astronomy with a few arcmin resolution. From 0.3 to 10 MeV it is a Compton telescope. Above 1 MeV, its multi-layers of double sided silicon strip detectors allow for Compton recoil electron tracking and the unique determination for incident photon direction. From 10 to 100 MeV the tracking feature is utilized for gamma-ray pair event reconstruction. Here we present TIGRE energy resolutions, background simulations and the development of the electronics readout system

Order in driven vortex lattices in superconducting Nb films with nanostructured pinning potentials

Driven vortex lattices have been studied in a material with strong pinning, such as Nb films. Samples in which natural random pinning coexists with artificial ordered arrays of defects (submicrometric Ni dots) have been fabricated with different geometries (square, triangular and rectangular). Three different dynamic regimes are found: for low vortex velocities, there is a plastic regime in which random defects frustrate the effect of the ordered array; then, for vortex velocities in the range 1-100 m/s, there is a sudden increase in the interaction between the vortex lattice and the ordered dot array, independent on the geometry. This effect is associated to the onset of quasi long range order in the vortex lattice leading to an increase in the overlap between the vortex lattice and the magnetic dots array. Finally, at larger velocities the ordered array-vortex lattice interaction is suppresed again, in agreement with the behavior found in numerical simulations.Comment: 8 text pages + 4 figure

Twenty Years of Galactic Observations in Searching for Bursts of Collapse Neutrinos with the Baksan Underground Scintillation Telescope

The results of twenty-year-long Galactic observations in neutrino radiation are summarized. Except for the recording of a neutrino signal from the supernova SN 1987A, no Galactic bursts of collapse neutrinos have been detected. An upper bound on the mean frequency of gravitational collapses in our Galaxy was obtained, $f_{collapse} (90$.Comment: latex, 7 pages, 2 eps figure

In vitro degradation and in vivo biocompatibility of chitosan-poly(butylene succinate) fiber mesh scaffolds

In tissue engineering, the evaluation of the host response to the biomaterial implantation must be assessed to determine the extent of the inflammatory reaction. We studied the degradation of poly(butylene succinate) and chitosan in vitro using lipase and lysozyme enzymes, respectively. The subcutaneous implantation of the scaffolds was performed to assess tissue response. The type of inflammatory cells present in the surrounding tissue, as well as within the scaffold, was determined histologically and by immunohistochemistry. In the presence of lipase or lysozyme, the water uptake of the scaffolds increased. Based on the weight loss data and scanning electron microscopy analysis, the lysozyme combined with lipase had a notable effect on the in vitro degradation of the scaffolds. The in vivo implantation showed a normal inflammatory response, with presence of neutrophils, in a first stage, and macrophages, lymphocytes, and giant cells in a later stage. Vascularization in the surrounding tissue and within the implant increased with time. Moreover, the collagen deposition increased with time inside the implant. In vivo, the scaffolds maintained the structural integrity. The degradation in vitro was faster and greater compared to that observed in vivo within the same time periods.Ana R Costa-Pinto was supported by the scholarship SFRH/24735/2005 from the Portuguese “Fundação para a Ciência e a Tecnologia” (FCT). This work was partially supported by the European Network of Excellence EXPERTISSUES (NMP3-CT-2004-500283) and FCT funded project Maxbone (PTDC/ SAU-ENB/115179/2009)

The WIP6 transcription factor TOO MANY LATERALS specifies vein type in C4 and C3 grass leaves

Grass leaves are invariantly strap shaped with an elongated distal blade and a proximal sheath that wraps around the stem. Underpinning this shape is a scaffold of leaf veins, most of which extend in parallel along the proximo-distal leaf axis. Differences between species are apparent both in the vein types that develop and in the distance between veins across the medio-lateral leaf axis. A prominent engineering goal is to increase vein density in leaves of C3 photosynthesizing species to facilitate the introduction of the more efficient C4 pathway. Here, we discover that the WIP6 transcription factor TOO MANY LATERALS (TML) specifies vein rank in both maize (C4) and rice (C3). Loss-of-function tml mutations cause large lateral veins to develop in positions normally occupied by smaller intermediate veins, and TML transcript localization in wild-type leaves is consistent with a role in suppressing lateral vein development in procambial cells that form intermediate veins. Attempts to manipulate TML function in rice were unsuccessful because transgene expression was silenced, suggesting that precise TML expression is essential for shoot viability. This finding may reflect the need to prevent the inappropriate activation of downstream targets or, given that transcriptome analysis revealed altered cytokinin and auxin signaling profiles in maize tml mutants, the need to prevent local or general hormonal imbalances. Importantly, rice tml mutants display an increased occupancy of veins in the leaf, providing a step toward an anatomical chassis for C4 engineering. Collectively, a conserved mechanism of vein rank specification in grass leaves has been revealed

Nonlinear analysis of EEG signals at different mental states

BACKGROUND: The EEG (Electroencephalogram) is a representative signal containing information about the condition of the brain. The shape of the wave may contain useful information about the state of the brain. However, the human observer can not directly monitor these subtle details. Besides, since bio-signals are highly subjective, the symptoms may appear at random in the time scale. Therefore, the EEG signal parameters, extracted and analyzed using computers, are highly useful in diagnostics. This work discusses the effect on the EEG signal due to music and reflexological stimulation. METHODS: In this work, nonlinear parameters like Correlation Dimension (CD), Largest Lyapunov Exponent (LLE), Hurst Exponent (H) and Approximate Entropy (ApEn) are evaluated from the EEG signals under different mental states. RESULTS: The results obtained show that EEG to become less complex relative to the normal state with a confidence level of more than 85% due to stimulation. CONCLUSIONS: It is found that the measures are significantly lower when the subjects are under sound or reflexologic stimulation as compared to the normal state. The dimension increases with the degree of the cognitive activity. This suggests that when the subjects are under sound or reflexologic stimuli, the number of parallel functional processes active in the brain is less and the brain goes to a more relaxed stat

Strategic Supply Function Competition with Private Information

A Bayesian supply function equilibrium is characterized in a market where firms have private information about their uncertain costs. It is found that with supply function competition, and in contrast to Bayesian Cournot competition, competitiveness is affected by the parameters of the information structure: supply functions are steeper with more noise in the private signals or more correlation among the costs parameters. In fact, for large values of noise or correlation supply functions are downward sloping, margins are larger than the Cournot ones, and as we approach the common value case they tend to the collusive level. Furthermore, competition in supply functions aggregates the dispersed information of firms (the equilibrium is privately revealing) while Cournot competition does not. The implication is that with the former the only source of deadweight loss is market power while with the latter we have to add private information. As the market grows large the equilibrium becomes competitive and we obtain an approximation to how many competitors are needed to have a certain degree of competitiveness

BG/L Calculations of the QCD Critical Temperature and Equation of State

We summarize the latest results from performing Lattice QCD calculations with two different discretization schemes, asqtad and p4fat3, on the LLNL BG/L supercomputer, and present a plan for continued running to complete the calculation of the QCD transition temperature and equation of state