4,619 research outputs found
Performance-related Funding of Universities: Does More Competition Lead to Grade Inflation?
German universities are regarded as being under-financed, inefficient, and performing below average if compared to universities in other European countries and the US. Starting in the 1990s, several German federal states implemented reforms to improve this situation. An important part of these reforms has been the introduction of indicator-based funding systems. These financing systems aimed at increasing the competition between universities by making their pubic funds dependent on their relative performance concerning different output measures, such as the share of students obtaining a degree or the amount of third party funds. This paper evaluates whether the indicator-based funding created unintended incentives, i.e. whether the reform caused grade inflation. Estimating mean as well as quantile treatment effects, we cannot support the hypothesis that increased competition between universities causes grade inflation.grade inflation, higher education funding, university competition
Performance-related Funding of Universities – Does more Competition Lead to Grade Inflation?
German universities are regarded as being under-financed, inefficient, and performing below average if compared to universities in other European countries and the US. Starting in the 1990s, several German federal states implemented reforms to improve this situation. An important part of these reforms has been the introduction of indicator-based funding systems. These financing systems aimed at increasing the competition between universities by making their public funds dependent on their relative performance concerning different output measures, such as the share of students obtaining a degree or the amount of third party funds. This paper evaluates whether the indicator-based funding created unintended incentives, i.e. whether the reform caused a grade inflation. Estimating mean as well as quantile treatment effects, we cannot support the hypothesis that increased competition between universities causes grade inflation.Grade inflation; higher education funding; university competition
Nicola Kaminski, Ex bello ars oder Ursprung der "Deutschen Poeterey". 2004
Eine umfassende Erklärung der Entwicklung der deutschen Literatur unter den Vorzeichen des Dreißigjährigen Krieges hat in den vergangenen 30 Jahren - seit Erich Trunz' Nachwort zum Opitz-Neudruck - niemand mehr in Angriff genommen. Nicola Kaminskis energischer Versuch verdient schon deswegen Anerkennung. Sie riskiert Thesen über die utopische Zielsetzung der deutschsprachigen Poesie nach 1624 und die konfessionspolitischen Sympathien ihrer Verfasser. Sie entläßt ihre Leser nach 550 Seiten mit der Erkenntnis, daß der Dreißigjährige Krieg Spuren in allen deutschsprachigen Dichtungen hinterlassen hat und die Dichter sich der Bewältigung des Kriegsleids verschrieben haben. In Sonetten, Klageliedern, Dramen und Romanen haben sie gegen Streit, Gewalt und mutwillige Verwüstung angeschrieben und sich mit den Folgen des Krieges auseinandergesetz
Parental background and other-regarding preferences in children
Other-regarding preferences are important for establishing and maintaining cooperative outcomes. In this paper, we study how formation of other-regarding preferences during childhood is affected by parental background. Our subjects, aged 4-12 years, are classified into other-regarding types based on simple binary choice dictator games. The main finding is that children of parents with low education are more spiteful, more selfish and less altruistic. This link is robust to controlling for a rich set of child characteristics and class fixed effects. The parental effects stand out against the overall development of preferences, as we find children to become less spiteful and more altruistic with increasing age. Our findings, complemented by an analysis of the World Values Survey data, suggest that low socio-economic status affects parental effort invested in instilling other-regarding preferences into children, making them less likely to acquire cooperative types of preferences
Electronic excitation of transition metal nitrides by light ions with keV energies
We investigated the specific electronic energy deposition by protons and He
ions with keV energies in different transition metal nitrides of technological
interest. Data were obtained from two different time-of-flight ion scattering
setups and show excellent agreement. For protons interacting with light
nitrides, i.e. TiN, VN and CrN, very similar stopping cross sections per atom
were found, which coincide with literature data of N2 gas for primary energies
<= 25 keV. In case of the chemically rather similar nitrides with metal
constituents from the 5th and 6th period, i.e. ZrN and HfN, the electronic
stopping cross sections were measured to exceed what has been observed for
molecular N2 gas. For He ions, electronic energy loss in all nitrides was found
to be significantly higher compared to the equivalent data of N2 gas.
Additionally, deviations from velocity proportionality of the observed specific
electronic energy loss are observed. A comparison with predictions from density
functional theory for protons and He ions yields a high apparent efficiency of
electronic excitations of the target for the latter projectile. These findings
are considered to indicate the contributions of additional mechanisms besides
electron hole pair excitations, such as electron capture and loss processes of
the projectile or promotion of target electrons in atomic collisions
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Prevention and treatment of venous thromboembolism in pregnancy in patients with hereditary antithrombin deficiency
Objective: The aims of the study reported here were to provide data from six pregnant subjects who were enrolled in a clinical trial of antithrombin (AT) concentrate, discuss other published case series and case reports, and provide general guidance for the use of AT concentrate for inherited AT deficiency in pregnancy. Methods: In the late 1980s, 31 AT-deficient subjects were enrolled in a prospective treatment trial of the plasma-derived AT concentrate Thrombate III®. Herein, newly available treatment data about the six pregnant subjects in the trial is tabulated and summarized. Results: All six experienced venous thromboembolism (VTE) during pregnancy, were dosed according to a weight-based protocol, and were treated concomitantly with anticoagulation. Loading doses of AT concentrate of 54–62 units/kg were followed by maintenance doses of 50%–100% of the loading dose for 3–10 days. At the time of labor, loading doses of 46–50 units/kg were followed by maintenance doses of 50%–75% of the loading dose for 5–7 days. None of the six experienced recurrent thrombosis while receiving treatment with AT concentrate. Conclusion: Currently we suggest that women with AT deficiency who are pregnant or postpartum and have a personal history of VTE or current VTE receive AT concentrates
An edit distance for Reeb graphs
We consider the problem of assessing the similarity of 3D shapes
using Reeb graphs from the standpoint of robustness under
perturbations. For this purpose, 3D objects are viewed as spaces
endowed with real-valued functions, while the similarity between
the resulting Reeb graphs is addressed through a graph edit
distance. The cases of smooth functions on manifolds and piecewise
linear functions on polyhedra stand out as the most interesting
ones. The main contribution of this paper is the introduction of a
general edit distance suitable for comparing Reeb graphs in these
settings. This edit distance promises to be useful for
applications in 3D object retrieval because of its stability
properties in the presence of noise
Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine KrasG12D-induced skin carcinogenesis in vivo
Background
The Ras and Notch signaling pathways are frequently activated during development to control many diverse cellular processes and are often dysregulated during tumorigenesis. To study the role of Notch and oncogenic Kras signaling in a progenitor cell population, Pdx1-Cre mice were utilized to generate conditional oncogenic KrasG12D mice with ablation of Notch1 and/or Notch2.
Methodology/Principal Findings
Surprisingly, mice with activated KrasG12D and Notch1 but not Notch2 ablation developed skin papillomas progressing to squamous cell carcinoma providing evidence for Pdx1 expression in the skin. Immunostaining and lineage tracing experiments indicate that PDX1 is present predominantly in the suprabasal layers of the epidermis and rarely in the basal layer. Further analysis of keratinocytes in vitro revealed differentiation-dependent expression of PDX1 in terminally differentiated keratinocytes. PDX1 expression was also increased during wound healing. Further analysis revealed that loss of Notch1 but not Notch2 is critical for skin tumor development. Reasons for this include distinct Notch expression with Notch1 in all layers and Notch2 in the suprabasal layer as well as distinctive p21 and β-catenin signaling inhibition capabilities.
Conclusions/Significance
Our results provide strong evidence for epidermal expression of Pdx1 as of yet not identified function. In addition, this finding may be relevant for research using Pdx1-Cre transgenic strains. Additionally, our study confirms distinctive expression and functions of Notch1 and Notch2 in the skin supporting the importance of careful dissection of the contribution of individual Notch receptors
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