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    High-temperature, gas-filled, ceramic rectifiers, thyratrons, and voltage- reference tubes Quarterly progress report no. 3, 15 Jun. - 14 Sep. 1965

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    High temperature, gas filled ceramic rectifiers, thyratrons, and voltage-reference tube

    High-temperature, gas-filled ceramic rectifiers, thyratrons, and voltage-reference tubes

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    Thyratron, capable of being operated as a rectifier and a voltage-reference tube, was constructed and tested for 1000 hours at temperatures to 800 degrees C. With current levels at 15 amps and peak voltages of 2000 volts and frequencies at 6000 cps, tube efficiency was greater than 97 percent

    High-temperature, long-life thyratron

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    Thallium and xenon filled thyratron was developed that operates at tube envelope temperatures up to 750 C. This tube performs at peak voltage ratings of 2000 V forward and reverse and at an average current rating of 15 A for up to 11,000 hours

    Development of high-temperature, gas-filled, ceramic rectifiers, thyratrons, and voltage-reference tubes Final report, Dec. 15, 1964 - Jan. 26, 1966

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    Development of high temperature gas filled ceramic rectifiers, thyratrons, and voltage-regulator tube

    The Consistent Newtonian Limit of Einstein's Gravity with a Cosmological Constant

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    We derive the `exact' Newtonian limit of general relativity with a positive cosmological constant Λ\Lambda. We point out that in contrast to the case with Λ=0\Lambda = 0 , the presence of a positive Λ\Lambda in Einsteins's equations enforces, via the condition Φ1| \Phi | \ll 1, on the potential Φ\Phi, a range Rmax(Λ)rRmin(Λ){\cal R}_{max}(\Lambda) \gg r \gg {\cal R}_{min} (\Lambda), within which the Newtonian limit is valid. It also leads to the existence of a maximum mass, Mmax(Λ){\cal M}_{max}(\Lambda). As a consequence we cannot put the boundary condition for the solution of the Poisson equation at infinity. A boundary condition suitably chosen now at a finite range will then get reflected in the solution of Φ\Phi provided the mass distribution is not spherically symmetric.Comment: Latex, 15 pages, no figures, errors correcte

    Dynamic cofilin phosphorylation in the control of lamellipodial actin homeostasis

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    During animal cell chemotaxis, signalling at the plasma membrane induces actin polymerisation to drive forward cell movement. Since the cellular pool of actin is limited, efficient protrusion formation also requires the coordinated disassembly of pre-existing actin filaments. To search for proteins that can monitor filamentous and globular actin levels to maintain the balance of polymerisation and disassembly, we followed changes in the proteome induced by RNA interference (RNAi)mediated alterations in actin signalling. This unbiased approach revealed an increase in the levels of an inactive, phosphorylated form of the actin-severing protein cofilin in cells unable to generate actin-based lamellipodia. Conversely, an increase in F-actin levels induced the dephosphorylation and activation of cofilin via activation of the Ssh phosphatase. Similarly, in the context of acute phosphoinositide 3-kinase (PI3K) signalling, dynamic changes in cofilin phosphorylation were found to depend on the Ssh phosphatase and on changes in lamellipodial Factin. These results indicate that changes in the extent of cofilin phosphorylation are regulated by Ssh in response to changes in the levels and/or organisation of F-actin. Together with the recent finding that Ssh phosphatase activity is augmented by F-actin binding, these results identify Ssh-dependent regulation of phosphorylated cofilin levels as an important feedback control mechanism that maintains actin filament homeostasis during actin signalling

    Higgs Portals for Thermal Dark Matter - EFT Perspectives and the NMSSM -

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    We analyze a low energy effective model of Dark Matter in which the thermal relic density is provided by a singlet Majorana fermion which interacts with the Higgs fields via higher dimensional operators. Direct detection signatures may be reduced if blind spot solutions exist, which naturally appear in models with extended Higgs sectors. Explicit mass terms for the Majorana fermion can be forbidden by a Z3Z_3 symmetry, which in addition leads to a reduction of the number of higher dimensional operators. Moreover, a weak scale mass for the Majorana fermion is naturally obtained from the vacuum expectation value of a scalar singlet field. The proper relic density may be obtained by the ss-channel interchange of Higgs and gauge bosons, with the longitudinal mode of the ZZ boson (the neutral Goldstone mode) playing a relevant role in the annihilation process. This model shares many properties with the Next-to-Minimal Supersymmetric extension of the Standard Model (NMSSM) with light singlinos and heavy scalar and gauge superpartners. In order to test the validity of the low energy effective field theory, we compare its predictions with those of the ultraviolet complete NMSSM. Extending our framework to include Z3Z_3 neutral Majorana fermions, analogous to the bino in the NMSSM, we find the appearance of a new bino-singlino well tempered Dark Matter region.Comment: 42 pages, 14 figures. v2: added references, published in JHE

    Studies in planetology, including the collection and interpretation of planetary information

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    The value of synoptic imaging of the planets is reported. The advantage of the Large Space Telescope, as compared with ground-based telescopes and planetary orbiters and flybys, is discussed. Desirable LST camera parameters and observing strategies are considered from the standpoint of synoptic imaging
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