Тенденції розвитку туристичної галузі в умовах глобальної нестабільності

Розглянуто питання розвитку світової туристичної галузі в умовах нестабільності та перспективи розвитку туризму на Україні.The problems of the global tourism industry in terms of instability and prospects for the development of tourism in Ukraine are discussed in the article.Рассмотрены вопросы развития мировой туристической отрасли в условиях нестабильности и перспективы развития туризма на Украине

Genetic engineering of peptide hormones : II. Possible polymorphism of preprolactin in cattle. Data of molecular cloning

Primary structure is determined of an insertion of a clone isolated from the library of hypophyseal cDNA of cattle by hybridization with a probe specific for prolactin. Analysis of nucleotide sequences showed that in the process of cloning, reorganization occurred in structure of preprolactin cDNA, including an inversion of the 5'-terminal and deletion of the central section of cDNA. Nevertheless, from structure of cDNA, nucleotide sequences can be deduced of extended 5'- and 3'-terminal sections of preprolactin mRNA in cattle with lengths of 257 and 551 nucleotide residues, respectively. When these sequences are compared to those established previously, some differences were found in primary structure. The most important of them is the presence of an additional codon which codes alanine at the position (-22) of the signal peptide. It is suggested that heterogeneity of preprolactin mRNA of cattle in the section coding the signal peptide is the result of alternative splicing, as was shown for preprolactin mRNA in rats

Enhanced four-wave mixing via elimination of inhomogeneous broadening by coherent driving of quantum transition with control fields

We show that atoms from wide velocity interval can be concurrently involved in Doppler-free two-photon resonant far from frequency degenerate four-wave mixing with the aid of auxiliary electromagnetic field. This gives rise to substantial enhancement of the output radiation generated in optically thick medium. Numerical illustrations addressed to typical experimental conditions are given.Comment: LaTeX2e, hyperref, 7 pages, 5 figures, to appear in PRA 1 august 200

Finding Low Degree Annihilators for a Boolean Function Using Polynomial Algorithms

Low degree annihilators for Boolean functions are of great interest in cryptology because of algebraic attacks on LFSR-based stream ciphers. Several polynomial algorithms for construction of low degree annihilators are introduced in this paper. The existence of such algorithms is studied for the following forms of the function representation: algebraic normal form (ANF), disjunctive normal form (DNF), conjunctive normal form (CNF), and arbitrary formula with the Boolean operations of negation, conjunction, and disjunction. For ANF and DNF of a Boolean function $f$ there exist polynomial algorithms that find the vector space $A_d (f)$ of all annihilators of degree $\leqslant d$. For CNF this problem is NP-hard. Nevertheless author introduces one polynomial algorithm that constructs some subspace of $A_d (f)$ having formula that represents $f$

RuDaCoP: The Dataset for Smartphone-based Intellectual Pedestrian Navigation

This paper presents the large and diverse dataset for development of smartphone-based pedestrian navigation algorithms. This dataset consists of about 1200 sets of inertial measurements from sensors of several smartphones. The measurements are collected while walking through different trajectories up to 10 minutes long. The data are accompanied by the high accuracy ground truth collected with two foot-mounted inertial measurement units and post-processed by the presented algorithms. The dataset suits both for training of intellectual pedestrian navigation algorithms based on learning techniques and for development of pedestrian navigation algorithms based on classical approaches. The dataset is accessible at http://gartseev.ru/projects/ipin2019

THE CONCEPT OF A MULTILEVEL MODEL OF UKRAINE'S CAPACITY AS A PLACE OF MEDICAL TOURISM: DEVELOPMENT FACTORS AND PROSPECTS

In the age of globalized medicine, medical tourism is gaining an important global perspective on health. The global medical tourism market is also following this trend; according to forecasts by Grand View Research, Inc., the size of the global medical tourism market is expected to reach $179.6 billion by 2026. Medical tourism brings direct foreign currency income and contributes to the overall development of any economy. It ensures not only the creation of new jobs, but also the growth of associated enterprises such as those in the business of pharmaceuticals, medicines and tourism

Organizational infrastructure of innovation processes in Russian Russia

The study presents the regional and national statistics, allowing drawing the conclusions about the state of the innovation process, its elements, and their relationships. The main result of the study is the identified “gap” between basic science as the object of creating innovations and manufacturing enterprises as the object of the implementation of innovations. According to the authors, there is a necessity for the process control for not only the creation, but the implementation of innovations in production; the formation of an infrastructure that can provide the interaction of science and industry, the transformation of scientific developments into the manufacturing process now. This structure should be a buffer zone between the elements of the innovation process, create an area of mutually beneficial cooperation. The article considers the evolution of scientific development transformation in production. The organizational model of “innovation-to-production” transfer established on the small innovative enterprises affiliated with the leading educational institutions is suggested. The merits and drawbacks of the organizational interaction models in the “higher education institution-the small innovative enterprise-the enterprise” chain are shown

Identification of Bacterial Clones Encoding Bovine Caseins by Direct Immunological Screening of the cDNA Library

A sensitive immunoassay was used to identify recombinant plasmids carrying cDNA fragments of bovine caseins in the cDNA library from bovine mammary gland mRNA. Colonies grown on nitrocellulose filters were lysed in situ and proteins from the lysates were blotted onto CNBr-activated cellulose filter paper. Antigens covalently bound to CNBr-activated paper or bound to nitrocellulose filters were detected by reaction with antiserum to caseins, followed by ^125I-labelled Staphylococcus aureus protein A and autoradiography. Six clones were found positive among 5400 of the cDNA library: 3-A1, 3-B2, 3-B5, 3-H7, 2-A5 and 2-C9. The molecular weights of chimeric pre-β-lactamase: casein proteins synthesized in Escherichia coli were estimated by immunoblotting. Colony hybridization and nucleotide sequence analysis showed that clone 3-B5 contained a cDNA fragment of bovine χ-casein, clone 3-H7 contained a cDNA fragment of β-casein, while clones 2-A5 and 2-C9 carried cDNA fragments of α_si-casein