Discrete Charge Dielectric Model of Electrostatic Energy

Studies on nanoscale materials merit careful development of an electrostatics model concerning discrete point charges within dielectrics. The discrete charge dielectric model treats three unique interaction types derived from an external source: Coulomb repulsion among point charges, direct polarization between point charges and their associated surface charge elements, and indirect polarization between point charges and surface charge elements formed by other point charges. The model yields the potential energy, U(N), stored in a general $N$ point charge system differing from conventional integral formulations, $1/2\int{\bm E}\cdot{\bm D}dV$ and $1/2\int\rho\Phi dV$, in a manner significant to the treatment of few electron systems.Comment: 1 figure, 2 parts, ep

Axion gauge symmetries and generalized Chern-Simons terms in N=1 supersymmetric theories

We compute the form of the Lagrangian of N=1 supersymmetric theories with gauged axion symmetries. It turns out that there appear generalized Chern-Simons terms that were not considered in previous superspace formulations of general N=1 theories. Such gaugings appear in supergravities arising from flux compactifications of superstrings, as well as from Scherk-Schwarz generalized dimensional reduction in M-theory. We also present the dual superspace formulation where axion chiral multiplets are dualized into linear multiplets.Comment: References added and few misprints correcte

Optical Gravitational Lensing Experiment. OGLE-1999-BUL-19: The First Multi-Peak Parallax Event

We describe a highly unusual microlensing event, OGLE-1999-BUL-19, which exhibits multiple peaks in its light curve. The Einstein radius crossing time for this event is approximately one year, which is unusually long. We show that the motion of the Earth induces these multiple peaks in the light curve, since the relative transverse velocity of the lens projected into the observer plane is very small (v = 12.5 km/s). This is the lowest velocity so far published and we believe that this is the first multiple-peak parallax event ever observed. We also believe that this event may be exhibiting slight binary-source signatures in addition to these parallax-induced multiple peaks. With spectroscopic observations it is possible to test this `parallax plus binary-source' hypothesis and (if this hypothesis turns out to be correct) to simultaneously fit both models and obtain a measurement of the lens mass. Furthermore, spectroscopic observations could also supply information regarding the lens properties, possibly providing another avenue for determining the lens mass. We found that most of the I-band blending is probably caused by light from the lens or a binary companion to the source. However, in the V-band, there appears to be a second blended source 0.35" away from the lensed source. HST observations will be very useful for understanding the nature of the blends. We also suggest that a radial velocity survey of all parallax events will be very useful for further constraining the lensing kinematics and understanding the origins of these events and the excess of long events toward the bulge.Comment: 36 pages, 7 figures. Accepted for publication in MNRA

Constraining the Radii of Neutron Stars with Terrestrial Nuclear Laboratory Data

Neutron star radii are primarily determined by the pressure of isospin asymmetric matter which is proportional to the slope of the nuclear symmetry energy. Available terrestrial laboratory data on the isospin diffusion in heavy-ion reactions at intermediate energies constrain the slope of the symmetry energy. Using this constraint, we show that the radius (radiation radius) of a 1.4 solar mass neutron star is between 11.5 (14.4) and 13.6 (16.3) km.Comment: 11 pages, 3 figures; version to be published in Phys. Lett.

Exploring Trading Strategies and Their Effects in the Foreign Exchange Market

One of the most critical issues that developers face in developing automatic systems for electronic markets is that of endowing the agents with appropriate trading strategies. In this article, we examine the problem in the foreign exchange (FX) market, and we use an agent‐based market simulation to examine which trading strategies lead to market states in which the stylized facts (statistical properties) of the simulation match those of the FX market transactions data. Our goal is to explore the emergence of the stylized facts, when the simulated market is populated with agents using different strategies: a variation of the zero intelligence with a constraint strategy, the zero‐intelligence directional‐change event strategy, and a genetic programming‐based strategy. A series of experiments were conducted, and the results were compared with those of a high‐frequency FX transaction data set. Our results show that the zero‐intelligence directional‐change event agents best reproduce and explain the properties observed in the FX market transactions data. Our study suggests that the observed stylized facts could be the result of introducing a threshold that triggers the agents to respond to periodic patterns in the price time series. The results can be used to develop decision support systems for the FX market

Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation

A role for WNT signalling in gastric carcinogenesis has been suggested due to two major observations. First, patients with germline mutations in adenomatous polyposis coli (APC) are susceptible to stomach polyps and second, in gastric cancer, WNT activation confers a poor prognosis. However, the functional significance of deregulated WNT signalling in gastric homoeostasis and cancer is still unclear. In this study we have addressed this by investigating the immediate effects of WNT signalling activation within the stomach epithelium. We have specifically activated the WNT signalling pathway within the mouse adult gastric epithelium via deletion of either glycogen synthase kinase 3 (GSK3) or APC or via expression of a constitutively active β-catenin protein. WNT pathway deregulation dramatically affects stomach homoeostasis at very short latencies. In the corpus, there is rapid loss of parietal cells with fundic gland polyp (FGP) formation and adenomatous change, which are similar to those observed in familial adenomatous polyposis. In the antrum, adenomas occur from 4 days post-WNT activation. Taken together, these data show a pivotal role for WNT signalling in gastric homoeostasis, FGP formation and adenomagenesis. Loss of the parietal cell population and corresponding FGP formation, an early event in gastric carcinogenesis, as well as antral adenoma formation are immediate effects of nuclear β-catenin translocation and WNT target gene expression. Furthermore, our inducible murine model will permit a better understanding of the molecular changes required to drive tumourigenesis in the stomach

Parallaxes and proper motions for 20 open clusters as based on the new Hipparcos catalogue

A new reduction of the astrometric data as produced by the Hipparcos mission has been published, claiming that the accuracies for nearly all stars brighter than magnitude $\mathrm{Hp}=8$ are improved, by up to a factor 4, compared to the original catalogue. As correlations between the underlying abscissa residuals have also been reduced by more than an order of magnitude to an insignificant level, our ability to determine reliable parallaxes and proper motions for open clusters should be improved. The new Hipparcos astrometric catalogue is used to derive mean parallax and proper motion estimates for 20 open clusters. The HR-diagrams of the nearest clusters are compared and combined to provide future input to sets of observational isochrones. The positions of the cluster HR diagrams are consistent within different groups of clusters shown for example by the near-perfect alignment of the sequences for the Hyades and Praesepe, for Coma Ber and UMa, and for the Pleiades, NGC 2516, and Blanco 1. The groups are mutually consistent when systematic differences in $\Delta c_0$ are taken into account, where the effect of these differences on the absolute magnitudes has been calibrated using field-star observations.Comment: 34 pages, 36 figures, 7 tables. Accepted for publication by A&

Remnant radio-loud AGN in the Herschel-ATLAS field

Only a small fraction of observed active galactic nuclei (AGN) display large-scale radio emission associated with jets, yet these radio-loud AGN have become increasingly important in models of galaxy evolution. In determining the dynamics and energetics of the radio sources over cosmic time, a key question concerns what happens when their jets switch off. The resulting ‘remnant' radio-loud AGN have been surprisingly evasive in past radio surveys, and therefore statistical information on the population of radio-loud AGN in their dying phase is limited. In this paper, with the recent developments of Low-Frequency Array (LOFAR) and the Very Large Array, we are able to provide a systematically selected sample of remnant radio-loud AGN in the Herschel-ATLAS field. Using a simple core-detection method, we constrain the upper limit on the fraction of remnants in our radio-loud AGN sample to 9 per cent, implying that the extended lobe emission fades rapidly once the core/jets turn off. We also find that our remnant sample has a wide range of spectral indices (−1.5 ⩽ α1400150 ⩽ −0.5), confirming that the lobes of some remnants may possess flat spectra at low frequencies just as active sources do. We suggest that, even with the unprecedented sensitivity of LOFAR, our sample may still only contain the youngest of the remnant population

First Observation of the Decays chi_{cJ} -> pi^0 pi^0 pi^0 pi^0

We present a study of the P-wave spin -triplet charmonium chi_{cJ} decays (J=0,1,2) into pi^0 pi^0 pi^0 pi^0. The analysis is based on 106 million \psiprime decays recorded with the BESIII detector at the BEPCII electron positron collider. The decay into the pi^0 pi^0 pi^0 pi^0 hadronic final state is observed for the first time. We measure the branching fractions B(chi_{c0} -> pi^0 pi^0 pi^0 pi^0)=(3.34 +- 0.06 +- 0.44)*10^{-3}, B(chi_{c1} -> pi^0 pi^0 pi^0 pi^0)=(0.57 +- 0.03 +- 0.08)*10^{-3}, and B(chi_{c2} -> pi^0 pi^0 pi^0 pi^0)=(1.21 +- 0.05 +- 0.16)*10^{-3}, where the uncertainties are statistical and systematical, respectively.Comment: 7 pages, 3 figure

The Mitochondrial Ca(2+) Uniporter: Structure, Function, and Pharmacology.

Mitochondrial Ca(2+) uptake is crucial for an array of cellular functions while an imbalance can elicit cell death. In this chapter, we briefly reviewed the various modes of mitochondrial Ca(2+) uptake and our current understanding of mitochondrial Ca(2+) homeostasis in regards to cell physiology and pathophysiology. Further, this chapter focuses on the molecular identities, intracellular regulators as well as the pharmacology of mitochondrial Ca(2+) uniporter complex