389 research outputs found
The North Star and the Atlantic 1848
This article explores the coverage of the 1848 uprisings in Europe by the North Star, a black newspaper edited by Frederick Douglass
Reclaiming Revolution: William Wells Brown's Irreducible Haitian Heroes
This article focuses on William Wells Brown's 1854 history of the Haitian Revolution
"Americans As They Really Are": The Colored American and the Illustration of National Identity
This article explores the illustrations that appeared in the Colored American (1837-1841), a black newspaper published in New York City
Chronicling White America
This forum contribution focuses on the racial politics of digitization
Genome-wide association study of CSF levels of 59 Alzheimer’s disease candidate proteins: Significant associations with proteins involved in amyloid processing and inflammation
Blake and the Black Newspaper
A contribution to a forum on Martin Delany, Blake; Or the Huts of America, ed. Jerome Mcgann
Apolipoprotein E and Alzheimer’s disease: The influence of apolipoprotein E on amyloid- and other amyloidogenic proteins
The Alzheimer\u27s Biomarker Consortium-Down Syndrome: Rationale and methodology
Introduction: Adults with Down syndrome (DS) are at exceptionally high risk for Alzheimer\u27s disease (AD), with virtually all individuals developing key neuropathological features by age 40. Identifying biomarkers of AD progression in DS can provide valuable insights into pathogenesis and suggest targets for disease modifying treatments.
Methods: We describe the development of a multi-center, longitudinal study of biomarkers of AD in DS. The protocol includes longitudinal examination of clinical, cognitive, blood and cerebrospinal fluid-based biomarkers, magnetic resonance imaging and positron emission tomography measures (at 16-month intervals), as well as genetic modifiers of AD risk and progression.
Results: Approximately 400 individuals will be enrolled in the study (more than 370 to date). The methodological approach from the administrative, clinical, neuroimaging, omics, neuropathology, and statistical cores is provided.
Discussion: This represents the largest U.S.-based, multi-site, biomarker initiative of AD in DS. Findings can inform other multidisciplinary networks studying AD in the general population
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