Combining multiple classifications of chemical structures using consensus clustering

Consensus clustering involves combining multiple clusterings of the same set of objects to achieve a single clustering that will, hopefully, provide a better picture of the groupings that are present in a dataset. This Letter reports the use of consensus clustering methods on sets of chemical compounds represented by 2D fingerprints. Experiments with DUD, IDAlert, MDDR and MUV data suggests that consensus methods are unlikely to result in significant improvements in clustering effectiveness as compared to the use of a single clustering method. (C) 2012 Elsevier Ltd. All rights reserved

Individual and Interactive Effects of Temperature x Salinity on the Survival Rate of Hemigrapsus sanguineus

The Hemigrapsus sanguineus, or Asian shore crab, is an invasive crab that is currently invading rocky intertidal habitat on oceanic coasts across the northeastern United States. The species is thought to have been brought over via ship ballast water from its native range of the Eastern Asian shorelines. Asian shore crabs were first reported in North America in 1988 at Cape May, NJ; where they spread to their current invasive range from the coasts of North Carolina to Maine. The Asian shore crab’s success as an invader has been attributed to its high reproductive rate, direct predation on competing crab species, superior competition for resources, and release from parasitism. Its tolerances of sub-optimal temperature and salinity may hamper the further spread of such a powerful invader is. Temperatures below 20°C and salinities below 25% have been shown through experiments to be unfavorable for survival rates of crabs collected from the NY coast of the Long Island Sound. My study found that Asian shore crabs have increased survival rates over x hours in cold water temperatures (12°C) when compared to 20°C and 27°C. I also find that as salinity decreases, survival rates decrease. The results of my study find that temperature and salinity likely each have their own individual effect on the survival of the crabs as well as an interactive, amplified, effect.Purchase College SUNYEnvironmental StudiesBachelor of ArtsKraemer, George P

In situ bioremediation of perchlorate in soil and groundwater

This project conducted a technology assessment for in-situ bioremediation of perchlorate in soil and groundwater and assessed the suitability of electon donor amendments

From Many to One: Consensus Inference in a MIP

A Model Intercomparison Project (MIP) consists of teams who each estimate the same underlying quantity (e.g., temperature projections to the year 2070), and the spread of the estimates indicates their uncertainty. It recognizes that a community of scientists will not agree completely but that there is value in looking for a consensus and information in the range of disagreement. A simple average of the teams' outputs gives a consensus estimate, but it does not recognize that some outputs are more variable than others. Statistical analysis of variance (ANOVA) models offer a way to obtain a weighted consensus estimate of outputs with a variance that is the smallest possible and hence the tightest possible 'one-sigma' and 'two-sigma' intervals. Modulo dependence between MIP outputs, the ANOVA approach weights a team's output inversely proportional to its variation. When external verification data are available for evaluating the fidelity of each MIP output, ANOVA weights can also provide a prior distribution for Bayesian Model Averaging to yield a consensus estimate. We use a MIP of carbon dioxide flux inversions to illustrate the ANOVA-based weighting and subsequent consensus inferences

"La motivazione e la professione infermieristica"

Essere pienamente convinti e fortemente motivati è sempre stato considerato un fattore fondamentale per portare a termine con successo le svariate scelte che la vita stessa pone davanti all’individuo. Ho scelto questo argomento per la convinzione che il paziente sia al centro dell’assistenza infermieristica; quindi partendo da questo presupposto è evidente che la motivazione dell’infermiere sia fondamentale per continuare a operare negli anni in maniera competente, efficiente e passionale. Nel primo capitolo vi è un’attenta analisi e considerazione delle varie teorie sulla motivazione. Nel secondo capitolo si parla della figura infermieristica, trattando i cambiamenti della professione nel tempo e anche la legislazione, lo stress e il burnout. Il terzo capitolo spiega in maniera dettagliata il progetto di ricerca “La motivazione e la professione infermieristica”. Lo studio è stato attuato tramite la somministrazione di questionari nel periodo di maggio-luglio 2014; i questionari sono stati somministrati contemporaneamente agli studenti del Corso di Laurea in Infermieristica e agli infermieri. L’obiettivo principale è comprendere in quale misura siano motivati sia gli studenti sia gli infermieri già operativi. Mentre l’obiettivo secondario è quello di comprendere se la motivazione possa variare con il passare del tempo; altro punto importante è quello di capire se gli infermieri siano soddisfatti del ruolo sociale dell’infermiere e se questa soddisfazione o insoddisfazione sia legata alla loro motivazion