"Is My Crown Better than Your Euro? Exchange Rates and Public Opinion on the European Single Currency"

The No to the euro in referendums in Denmark and Sweden has been characterized as a public rebellion against an elite project and a sign of a general Euroscepticism among the citizens. However, it is often ignored that support for the euro fluctuates significantly over time in these countries, and hence analysing referendum outcomes simply in terms on static factors will provide only part of the explanation. In contrast to existing studies, this paper provides an analysis of the short-term dynamics in public support for the euro in the period leading up to the referendums. We thus address the question of why public attitudes towards monetary integration vary over time. We argue that at least part of the answer can be found in exchange rate fluctuations. Existing studies have neglected the fact that the national currency is not only a purely monetary indicator, but also carries symbolic weight. The public is therefore less likely to surrender their national currency when it is strong than when it is weak. They are also less willing to accept a replacement currency (e.g. the euro) when it is seen as weak vis-à-vis other world currencies. Our analysis of the two euro campaigns lends credence to our proposition that exchange rates matter. Moreover, we test impact of exchange rate changes on support of the euro using time series analysis. We find that the rapid fall in the value of the euro vis-à-vis the dollar contributed to the Danish rejection of the euro, whereas the strength of the Swedish currency made the Swedes more reluctant to relinquish their crown

\u27Dracula: Bloodlines\u27 and the Role of Women

The writing process began after attending the Dracula Bloodlines ballet. While watching the performance, the integral role of women stood out to me and I decided it would be a good topic to write about. From there, it was a pretty easy process. I used the program to help support my ideas and make the essay complete. Editor\u27s note: This paper received first prize ($100)

HPLC-HRMS Quantification of the Ichthyotoxin Karmitoxin from Karlodinium armiger

Being able to quantify ichthyotoxic metabolites from microalgae allows for the determination of ecologically-relevant concentrations that can be simulated in laboratory experiments, as well as to investigate bioaccumulation and degradation. Here, the ichthyotoxin karmitoxin, produced by Karlodinium armiger, was quantified in laboratory-grown cultures using high-performance liquid chromatography (HPLC) coupled to electrospray ionisation high-resolution time-of-flight mass spectrometry (HRMS). Prior to the quantification of karmitoxin, a standard of karmitoxin was purified from K. armiger cultures (80 L). The standard was quantified by fluorescent derivatisation using Waters AccQ-Fluor reagent and derivatised fumonisin B1 and fumonisin B2 as standards, as each contain a primary amine. Various sample preparation methods for whole culture samples were assessed, including six different solid phase extraction substrates. During analysis of culture samples, MS source conditions were monitored with chloramphenicol and valinomycin as external standards over prolonged injection sequences (>12 h) and karmitoxin concentrations were determined using the response factor of a closely eluting iturin A2 internal standard. Using this method the limit of quantification was 0.11 μg·mL−1, and the limit of detection was found to be 0.03 μg·mL−1. Matrix effects were determined with the use of K. armiger cultures grown with 13C-labelled bicarbonate as the primary carbon source

Low-Coders, No-Coders, and Citizen Developers in Demand: Examining Knowledge, Skills, and Abilities Through a Job Market Analysis

The emergence of low-code/no-code (LCNC) platform technologies and the resulting increase in citizen development programs are facilitating the democratization of the design, development, and deployment of digital solutions. Citizen developers, non-technical employees who leverage LCNC platforms, are at the heart of this trend. While many firms perceive LCNC and citizen development as a crucial component of their digital transformation strategy, little is known about the evolving roles in this field or the necessary knowledge, skills, and abilities (KSA). To address this knowledge gap, we processed 113,106 job postings published on Indeed.com. Our topic modeling methodology identified 34 KSA topics and classified them into the three domains platform, business, and technology. We contribute to research by empirically demonstrating which competencies are required to successfully work in the LCNC field. Our findings can guide individual professionals and organizations alike

Karmitoxin: An amine containing polyhydroxy-polyene toxin from the marine dinoflagellate Karlodinium armiger

Marine algae from the genus Karlodinium are known to be involved in fish-killing events worldwide. Here we report for the first time the chemistry and bioactivity of a natural product from the newly described mixotrophic dinoflagellate Karlodinium armiger. Our work describes the isolation and structural characterization of a new polyhydroxy-polyene named karmitoxin. The structure elucidation work was facilitated by use of 13C enrichment and high-field 2D NMR spectroscopy, where 1H–13C long-range correlations turned out to be very informative. Karmitoxin is structurally related to amphidinols and karlotoxins; however it differs by containing the longest carbon–carbon backbone discovered for this class of compounds, as well as a primary amino group. Karmitoxin showed potent nanomolar cytotoxic activity in an RTgill-W1 cell assay as well as rapid immobilization and eventual mortality of the copepod Acartia tonsa, a natural grazer of K. armiger