404 research outputs found
5-fluorocytosine resistance is associated with hypermutation and alterations in capsule biosynthesis in Cryptococcus
The role of age of disclosure of biological origins in the psychological wellbeing of adolescents conceived by reproductive donation: a longitudinal study from age 1 to age 14.
BACKGROUND: The question of whether children should be told of their biological origins is one of the most controversial issues regarding the birth of children through donated eggs, sperm, embryos or surrogacy. METHODS: In the sixth phase of this longitudinal study when the children were aged 14 years, family relationships and adolescent adjustment were examined in 87 families created through reproductive donation and 54 natural conception families. The quality of family relationships was assessed by standardised interview with mothers and by standardised questionnaires and an observational measure with mothers and adolescents. Adolescent adjustment was assessed using standardised questionnaires. Systematic information on whether and when parents had told children about their biological origins was obtained at earlier phases of the study. RESULTS: There were no overall differences between disclosing families and either nondisclosing or natural conception families. However, within the disclosing families, more positive family relationships and higher levels of adolescent wellbeing were found for adolescents who had been told about their biological origins before age 7. CONCLUSIONS: The earlier children born through reproductive donation are told about their biological origins, the more positive are the outcomes in terms of the quality of family relationships and psychological wellbeing at adolescence
Leveraging implementation science to reduce inequities in Children’s mental health care: highlights from a multidisciplinary international colloquium
Background and purpose: Access to evidence-based mental health care for children is an international priority. However, there are significant challenges to advancing this public health priority in an efficient and equitable manner. The purpose of this international colloquium was to convene a multidisciplinary group of health researchers to build an agenda for addressing disparities in mental health care access and treatment for children and families through collaboration among scholars from the United States and Europe engaged in innovative implementation science and mental health services research. Key highlights: Guided by the Exploration, Preparation, Implementation, and Sustainment (EPIS) Framework, presentations related to inner, outer, and bridging context factors that impact the accessibility and quality of mental health evidence-based practices (EBPs) for children and families. Three common topics emerged from the presentations and discussions from colloquium participants, which included: 1) the impact of inner and outer context factors that limit accessibility to EBPs across countries, 2) strategies to adapt EBPs to improve their fit in different settings, 3) the potential for implementation science to address emerging clinical and public health concerns. Implications: The common topics discussed underscored that disparities in access to evidence-based mental health care are prevalent across countries. Opportunities for cross-country and cross-discipline learnings and collaborations can help drive solutions to address these inequities, which relate to the availability of a trained and culturally appropriate workforce, insurance reimbursement policies, and designing interventions and implementation strategies to support sustained use of evidence-based practices
Parents and Children Who Are Estranged in Adulthood: A Review and Discussion of the Literature.
This review examines what is known about estrangement between parents and their adult children in terms of definition, prevalence, causes, and consequences. Estrangement has been defined and conceptualised in different ways, although most definitions have focused on the negative quality of the relationship and the voluntarily or intentional decision of at least one family member to initiate and maintain distance. A diverse range of factors which are often interlinked has been found to contribute to estrangement. The consequences of estrangement from a parent or child include experiencing reduced levels of psychological well-being, feelings of loss, and experiences and/or perceptions of stigma. The estrangement literature has the potential to reveal variation in the quality of parent-child relationships in adulthood so that family scholars can move beyond our assumptions and understand family relationships as they are, rather than how they could or ‘should’ be
Jena and Auerstadt: Reorganization of the German Military from 1807-1945
The twin battles of Jena and Auerstadt in 1806 and the defeat of the Prussian army by Napoleon I set in motion a series of reforms that transitioned Prussia into a modern state both economically and militarily. From these reforms and key reformers, the Prussian state established itself amongst other European powers of the time helping defeat Napoleon in 1815 ending the Napoleonic period. After the Napoleonic age, the Prussian state again faced a dire situation during the 1848 revolutions and whether it would continue the reforms through a conservative or liberal approach. The military reforms of the 1850s during the Bismarckian era eventually succeeded in the successful wars accumulating in German unification in 1871. From this period forward, Prussian reforms transitioned into Imperial Germany during World War I (1914-1918) and finally climaxed with the creation of the Wehrmacht in World War II (1939-1945). The battles of Jena and Auerstadt in 1806 are significant in that they translate and connect to the creation of a modern Prussian army which then transitions to the modern Wehrmacht in the 1930s. The symbolism of the Prussian reforms in 1807-1813 is evident in the history of German and Prussian militarism and the events in Europe from 1807-1945
Radial Velocity Studies of Close Binary Stars. XI
Radial-velocity measurements and sine-curve fits to the orbital radial
velocity variations are presented for ten close binary systems: DU Boo, ET Boo,
TX Cnc, V1073 Cyg, HL Dra, AK Her, VW LMi, V566 Oph, TV UMi and AG Vir. By this
contribution, the DDO program has reached the point of 100 published radial
velocity orbits. The radial velocities have been determined using an improved
fitting technique which uses rotational profiles to approximate individual
peaks in broadening functions.
Three systems, ET Boo, VW LMi and TV UMi, were found to be quadruple while AG
Vir appears to be a spectroscopic triple. ET Boo, a member of a close visual
binary with years, was previously known to be a multiple
system, but we show that the second component is actually a close,
non-eclipsing binary. The new observations enabled us to determine the
spectroscopic orbits of the companion, non-eclipsing pairs in ET Boo and VW
LMi. The particularly interesting case is VW LMi, where the period of the
mutual revolution of the two spectroscopic binaries is only 355 days.
While most of the studied eclipsing pairs are contact binaries, ET Boo is
composed of two double-lined detached binaries and HL Dra is single-lined
detached or semi-detached system. Five systems of this group were observed
spectroscopically before: TX Cnc, V1073 Cyg, AK Her (as a single-lined binary),
V566 Oph, AG Vir, but our new data are of much higher quality than the previous
studies.Comment: Accepted by AJ, August 2006, 10 figures, 3 table
GJ 3236: a new bright, very low-mass eclipsing binary system discovered by the MEarth observatory
We report the detection of eclipses in GJ 3236, a bright (I = 11.6) very low
mass binary system with an orbital period of 0.77 days. Analysis of light- and
radial velocity curves of the system yielded component masses of 0.38 +/- 0.02
and 0.28 +/- 0.02 Msol. The central values for the stellar radii are larger
than the theoretical models predict for these masses, in agreement with the
results for existing eclipsing binaries, although the present 5% observational
uncertainties limit the significance of the larger radii to approximately 1
sigma. Degeneracies in the light curve models resulting from the unknown
configuration of surface spots on the components of GJ 3236 currently dominate
the uncertainties in the radii, and could be reduced by obtaining precise,
multi-band photometry covering the full orbital period. The system appears to
be tidally synchronized and shows signs of high activity levels as expected for
such a short orbital period, evidenced by strong Halpha emission lines in the
spectra of both components. These observations probe an important region of
mass-radius parameter space around the predicted transition to fully-convective
stellar interiors, where there are a limited number of precise measurements
available in the literature.Comment: 14 pages, 5 figures, 10 tables, emulateapj format. Accepted for
publication in Ap
Close binary stars in the solar-age Galactic open cluster M67
We present multi-colour time-series CCD photometry of the solar-age galactic
open cluster M67 (NGC 2682). About 3600 frames spread over 28 nights were
obtained with the 1.5 m Russian-Turkish and 1.2 m Mercator telescopes.
High-precision observations of the close binary stars AH Cnc, EV Cnc, ES Cnc,
the Scuti type systems EX Cnc and EW Cnc, and some long-period
variables belonging to M67 are presented. Three full multi-colour light curves
of the overcontact binary AH Cnc were obtained during three observing seasons.
Likewise we gathered three light curves of EV Cnc, an EB-type binary, and two
light curves of ES Cnc, a blue straggler binary. Parts of the light change of
long-term variables S1024, S1040, S1045, S1063, S1242, and S1264 are obtained.
Period variation analysis of AH Cnc, EV Cnc, and ES Cnc were done using all
times of mid-eclipse available in the literature and those obtained in this
study. In addition, we analyzed multi-colour light curves of the close binaries
and also determined new frequencies for the Scuti systems. The
physical parameters of the close binary stars were determined with simultaneous
solutions of multi-colour light and radial velocity curves. Finally we
determined the distance of M67 as 857(33) pc via binary star parameters, which
is consistent with an independent method from earlier studies.Comment: 12 pages, 9 Figures, 13 Table
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