Deformation of an elastic cell in a uniform stream and in a circulatory flow

The deformation of a circular, inextensible elastic cell is examined when the cell is placed into two different background potential flows: a uniform stream and a circulatory flow induced by a point vortex located inside the cell. In a circulatory flow a cell may deform into a mode m shape with m-fold rotational symmetry. In a uniform stream, shapes with two-fold rotational symmetry tend to be selected. In a weak stream a cell deforms linearly into an ellipse with either its major or its minor axis aligned with the oncoming flow. This marks an interesting difference with a bubble with constant surface tension in a uniform stream, which can only deform into a mode 2 shape with its major axis perpendicular to the stream (Vanden-Broeck & Keller, 1980b). In general, as the strength of the uniform stream is increased from zero, solutions emerge continuously from the cell configurations in quiescent fluid found by Flaherty et al. (1972). A richly populated solution space is described with multiple solution branches which either terminate when a cell reaches a state with a point of self-contact or loop round to continuously connect cell states which exist under identical conditions in the absence of flow

Modelling soil moisture for a grassland and a woodland site in south-east England

International audienceThis paper describes a comparison between two soil moisture prediction models. One is MORECS (Met Office Rainfall and Evaporation Calculation Scheme), the Met Office soil moisture model that is used by agriculture, flood modellers and weather forecasters to initialise their models. The other is MOSES (Met Office Surface Exchange Scheme), modified with a runoff generation module. The models are made compatible by increasing the vegetation information available to MOSES. Both models were run with standard parameters and were driven using meteorological observations at Wallingford (1995-1997). Detailed soil moisture measurements were available at a grassland site and a woodland site in this area. The comparison between the models and the observed soil moisture indicated that, for the grassland site, MORECS dried out too quickly in the spring and, for the woodland site, was too wet. Overall, the performance of MOSES was superior. The soil moisture predicted by the new, modified MOSES will be included as a product of Nimrod - the 5 km x 5km gridded network of observed meteorological data across the UK. Keywords: Soil moisture, model, observation, field capacit

Solitary waves on a ferrofluid jet

The propagation of axisymmetric solitary waves on the surface of an otherwise cylindrical ferrofluid jet subjected to a magnetic field is investigated. An azimuthal magnetic field is generated by an electric current flowing along a stationary metal rod which is mounted along the axis of the moving jet. A numerical method is used to compute fully-nonlinear travelling solitary waves and predictions of elevation waves and depression waves by Rannacher & Engel (2006) using a weakly-nonlinear theory are confirmed in the appropriate ranges of the magnetic Bond number. New nonlinear branches of solitary wave solutions are identified. As the Bond number is varied, the solitary wave profiles may approach a limiting configuration with a trapped toroidal-shaped bubble, or they may approach a static wave (i.e. one with zero phase speed). For a sufficiently large axial rod, the limiting profile may exhibit a cusp

Phase-field approach to heterogeneous nucleation

We consider the problem of heterogeneous nucleation and growth. The system is described by a phase field model in which the temperature is included through thermal noise. We show that this phase field approach is suitable to describe homogeneous as well as heterogeneous nucleation starting from several general hypotheses. Thus we can investigate the influence of grain boundaries, localized impurities, or any general kind of imperfections in a systematic way. We also put forward the applicability of our model to study other physical situations such as island formation, amorphous crystallization, or recrystallization.Comment: 8 pages including 7 figures. Accepted for publication in Physical Review

Improved modelling of Siberian river flow through the use of an alternative frozen soil hydrology scheme in a land surface model

A parameterisation to incorporate the effects of frozen soil on modelled hydrology is described and implemented within a land surface model, the Joint UK Land Surface Environment Simulator. It is shown to generally improve the modelled flow of Siberian rivers compared to observations, specifically in seasons of freezing or thawing soil. Most noticeably, the revised model increases the snowmelt flow peak by 26–100% compared to the control model thereby better matching observed flows. The model physics resulting in the changes to river flow are discussed and attention is given to the effect of inaccuracies in snowfall driving data which can hinder the comparison of new model processes

Dobutamine stress MRI in pulmonary hypertension: relationships between stress pulmonary artery relative area change, RV performance, and 10-year survival

In pulmonary hypertension (PH), right ventricular (RV) performance determines survival. Pulmonary artery (PA) stiffening is an important biomechanical event in PH and also predicts survival based on the PA relative area change (RAC) measured at rest using magnetic resonance imaging (MRI). In this exploratory study, we sought to generate novel hypotheses regarding the influence of stress RAC on PH prognosis and the interaction between PA stiffening, RV performance and survival. Fifteen PH patients underwent dobutamine stress-MRI (ds-MRI) and right heart catheterization. RACREST, RACSTRESS, and ΔRAC (RAC STRESS – RAC REST) were correlated against resting invasive hemodynamics and ds-MRI data regarding RV performance and RV-PA coupling efficiency (n’vv [RV stroke volume/RV end-systolic volume]). The impact of RAC, RV data, and n’vv on ten-year survival were determined using Kaplan–Meier analysis. PH patients with a low ΔRAC (<−2.6%) had a worse long-term survival (log-rank P = 0.045, HR for death = 4.46 [95% CI = 1.08–24.5]) than those with ΔRAC ≥ −2.6%. Given the small sample, these data should be interpreted with caution; however, low ΔRAC was associated with an increase in stress diastolic PA area indicating proximal PA stiffening. Associations of borderline significance were observed between low RACSTRESS and low n’vvSTRESS, Δη’VV, and ΔRVEF. Further studies are required to validate the potential prognostic impact of ΔRAC and the biomechanics potentially connecting low ΔRAC to shorter survival. Such studies may facilitate development of novel PH therapies targeted to the proximal PA

Towards a generalisation of formal concept analysis for data mining purposes

In this paper we justify the need for a generalisation of Formal Concept Analysis for the purpose of data mining and begin the synthesis of such theory. For that purpose, we first review semirings and semimodules over semirings as the appropriate objects to use in abstracting the Boolean algebra and the notion of extents and intents, respectively. We later bring to bear powerful theorems developed in the field of linear algebra over idempotent semimodules to try to build a Fundamental Theorem for K-Formal Concept Analysis, where K is a type of idempotent semiring. Finally, we try to put Formal Concept Analysis in new perspective by considering it as a concrete instance of the theory developed

Expectations and experiences of gamete donors and donor-conceived adults searching for genetics relatives using DNA linking through a voluntary register

STUDY QUESTION: What are the experiences of donor-conceived adults and donors who are searching for a genetic link through the use of a DNA-based voluntary register service? SUMMARY ANSWER: Donor-conceived adults and donors held positive beliefs about their search and although some concerns in relation to finding a genetically linked relative were reported, these were not a barrier to searching. WHAT IS KNOWN ALREADY: Research with donor-conceived people has consistently identified their interest in learning about-and in some cases making contact with-their donor and other genetic relatives. However, donor-conceived individuals or donors rarely have the opportunity to act on these desires. STUDY DESIGN, SIZE, AND DURATION: A questionnaire was administered for online completion using Bristol Online Surveys. The survey was live for 3 months and responses were collected anonymously. PARTICIPANTS/MATERIALS, SETTING, AND METHODS: The survey was completed by 65 donor-conceived adults, 21 sperm donors and 5 oocyte donors who had registered with a DNA-based voluntary contact register in the UK. The questionnaire included socio-demographic questions, questions specifically developed for the purposes of this study and the standardized Aspects of Identity Questionnaire (AIQ). MAIN RESULTS AND THE ROLE OF CHANCE: Motivations for searching for genetic relatives were varied, with the most common reasons being curiosity and passing on information. Overall, participants who were already linked and those awaiting a link were positive about being linked and valued access to a DNA-based register. Collective identity (reflecting self-defining feelings of continuity and uniqueness), as assessed by the AIQ, was significantly lower for donor-conceived adults when compared with the donor groups (P 0.05) for donor-conceived adults. LIMITATIONS, REASONS FOR CAUTION: Participants were members of a UK DNA-based registry which is unique. It was therefore not possible to determine how representative participants were of those who did not register for the service, those in other countries or of those who do not seek information exchange or contact. WIDER IMPLICATIONS OF THE FINDINGS: This is the first survey exploring the experiences of donor-conceived adults and donors using a DNA-based voluntary register to seek information about and contact with genetic relatives and the first to measure aspects of identity using standardized measures. Findings provide valuable information about patterns of expectations and experiences of searching through DNA linking, identity and of having contact in the context of donor conception that will inform future research, practice and policy development