Comet Halley returns: A teachers' guide 1985-1986

This booklet has been put together as an aid for teachers in elementary and secondary schools. It is divided into two distinct parts. The first part is a brief tutorial which introduces some of the most important concepts about comets, including their historical significance. A list of selected readings is provided at the end of the booklet. The second part of the booklet contains a number of suggested activities, built around the comet. These include both classroom exercises and carefully described field work to observe the comet. Guidance is provided on where to look for the comet, how to observe it, and to photograph it

Psychosis following a stroke to the cerebellum and midbrain: a case report

BACKGROUND: There is growing evidence that the cerebellum serves an important role in controlling affect and cognition, and its pathology has been implicated in several psychiatric disorders. Furthermore, the brainstem’s role in cognition and affect has been historically overlooked. Neuroimaging studies and an increasing number of case reports indicate cognitive deficits and hallucinatory phenomena after isolated brainstem lesions. CASE PRESENTATION: We report a 56-year-old man who developed persistent persecutory delusions, hallucinations, cognitive impairment and flattened affect following an extensive bilateral cerebellar stroke with involvement of the midbrain. CONCLUSIONS: This is one of the few reported cases of unremitting psychosis secondary to cerebellar and mesencephalic vascular infarction. We suggest, based on the distribution of the patient’s lesions, that his corresponding symptoms are a result of a disruption to cerebrocerebellar pathways. This article briefly reviews recent pathophysiological explanations behind the psychosis associated with brainstem and cerebellar lesions, the treatment, as well as the relation of these structures to each other

Relationships between Circulating Urea Concentrations and Endometrial Function in Postpartum Dairy Cows

Both high and low circulating urea concentrations, a product of protein metabolism, are associated with decreased fertility in dairy cows through poorly defined mechanisms. The rate of involution and the endometrial ability to mount an adequate innate immune response after calving are both critical for subsequent fertility. Study 1 used microarray analysis to identify genes whose endometrial expression 2 weeks postpartum correlated significantly with the mean plasma urea per cow, ranging from 3.2 to 6.6 mmol/L. The biological functions of 781 mapped genes were analysed using Ingenuity Pathway Analysis. These were predominantly associated with tissue turnover (e.g., BRINP1, FOXG1), immune function (e.g., IL17RB, CRISPLD2), inflammation (e.g., C3, SERPINF1, SERPINF2) and lipid metabolism (e.g., SCAP, ACBD5, SLC10A). Study 2 investigated the relationship between urea concentration and expression of 6 candidate genes (S100A8, HSP5A, IGF1R, IL17RB, BRINP1, CRISPLD2) in bovine endometrial cell culture. These were treated with 0, 2.5, 5.0 or 7.5 mmol/L urea, equivalent to low, medium and high circulating values with or without challenge by bacterial lipopolysaccharide (LPS). LPS increased S100A8 expression as expected but urea treatment had no effect on expression of any tested gene. Examination of the genes/pathways involved suggests that plasma urea levels may reflect variations in lipid metabolism. Our results suggest that it is the effects of lipid metabolism rather than the urea concentration which probably alter the rate of involution and innate immune response, in turn influencing subsequent fertility

A degenerate three-level laser with a parametric amplifier

The aim of this paper is to study the squeezing and statistical properties of the light produced by a degenerate three-level laser whose cavity contains a degenerate parametric amplifier. In this quantum optical system the top and bottom levels of the three-level atoms injected into the laser cavity are coupled by the pump mode emerging from the parametric amplifier. For a linear gain coefficient of 100 and for a cavity damping constant of 0.8, the maximum intracavity squeezing is found at steady state and at threshold to be 93%.Comment: 8 pages, 4 figures, published versio

Fluctuations of Quantum Radiation Pressure in Dissipative Fluid

Using the generalized Langevin equations involving the stress tensor approach, we study the dynamics of a perfectly reflecting mirror which is exposed to the electromagnetic radiation pressure by a laser beam in a fluid at finite temperature. Based on the fluctuation-dissipation theorem, the minimum uncertainty of the mirror's position measurement from both quantum and thermal noises effects including the photon counting error in the laser interferometer is obtained in the small time limit as compared with the "standard quantum limit". The result of the large time behavior of fluctuations of the mirror's velocity in a dissipative environment can be applied to the laser interferometer of the ground-based gravitational wave detector.Comment: 8 pages. Version published in Physics Letters

Quantum enhanced positioning and clock synchronization

A wide variety of positioning and ranging procedures are based on repeatedly sending electromagnetic pulses through space and measuring their time of arrival. This paper shows that quantum entanglement and squeezing can be employed to overcome the classical power/bandwidth limits on these procedures, enhancing their accuracy. Frequency entangled pulses could be used to construct quantum positioning systems (QPS), to perform clock synchronization, or to do ranging (quantum radar): all of these techniques exhibit a similar enhancement compared with analogous protocols that use classical light. Quantum entanglement and squeezing have been exploited in the context of interferometry, frequency measurements, lithography, and algorithms. Here, the problem of positioning a party (say Alice) with respect to a fixed array of reference points will be analyzed.Comment: 4 pages, 2 figures. Accepted for publication by Natur

Approaching the Heisenberg limit with two mode squeezed states

Two mode squeezed states can be used to achieve Heisenberg limit scaling in interferometry: a phase shift of $\delta \phi \approx 2.76 /$ can be resolved. The proposed scheme relies on balanced homodyne detection and can be implemented with current technology. The most important experimental imperfections are studied and their impact quantified.Comment: 4 pages, 7 figure