498 research outputs found
Recent Developments: Reagan v. Rider: Stepparent Committing Child Abuse Liable for Intentional Infliction of Emotional Distress
Ressourcen-Provisionierungsverfahren zur Erweiterung energetischer Freiheitsgrade von Rechenzentren unter Veränderung der IT-Last
Die Leistungsaufnahme von Rechenzentren wächst stetig und stellt ein relevantes Volumen im Energiesektor dar, sie lässt sich allerdings nicht bzw. nur unzureichend steuern. Maßgeblich wird die Leistungsaufnahme von der Rechenleistung bestimmt, die durch die jeweils betriebenen Applikationen abgerufen wird. In dieser Arbeit wird das auf dem Prinzip einer Ressourcen-Überprovisionierung beruhende Online Heuristic Machine Allocation (OHMA)-Verfahren vorgestellt. Mittels Server-Virtualisierung als Basis-Technologie werden virtuelle Maschinen als Vehikel zum Verschieben von Rechenlast verwendet und so eine Serverauslastung erzeugt, die einer geforderten Leistungsaufnahme entspricht. Eine Steuerung der Serverleistungsaufnahme wird so ermöglicht. Das Verfahren wird als Automaten-Modell in der Simulationsumgebung Uppaal modelliert und anhand von Datensätzen aus der Industrie evaluiert. Es wird eine Leistungsanpassung von bis zu 50% mit der Technik einer Ressourcen-Überprovisionierung bei linearer Komplexität des Verfahrens erreicht
Recasting the Parentative: Seeking Balance Amidst the Busyness
What stereotypes about working parents exist within the culture of academic libraries? In what ways are working mothers and fathers impacted by these stereotypes? How can institutions work to challenge these stereotypes and provide support for academic librarians who are balancing career advancement and family obligations? These are the three primary questions this panel will seek to address as part of “Recasting the Parentative: Seeking balance amidst the busyness.” Four panelists will discuss the preliminary results of a study of academic librarian-parent stereotypes and how those stereotypes affect academic library work. They will explore stories from academic librarians about their experiences as mothers and fathers in the workplace: how their roles as caretakers are perceived by their colleagues and how those perceptions impact aspects of academic work, including individual professionalization, institutional efficiency, collegiality, and career advancement. Furthermore, the panelists will offer recommendations for ways in which institutions can address the effects of these stereotypes. Audience members will be encouraged to share their experiences and offer advice to their colleagues. We want this panel to facilitate a brave space for discussing sensitive issues relating to the tension between being both full-time caretakers and full-time academics
Donor KIR B Genotype Improves Progression-Free Survival of Non-Hodgkin Lymphoma Patients Receiving Unrelated Donor Transplantation
Donor killer immunoglobulin-like receptor (KIR) genotypes are associated with relapse protection and survival after allotransplantation for acute myelogenous leukemia. We examined the possibility of a similar effect in a cohort of 614 non-Hodgkin lymphoma (NHL) patients receiving unrelated donor (URD) T cell-replete marrow or peripheral blood grafts. Sixty-four percent (n = 396) of donor-recipient pairs were 10/10 allele HLA matched and 26% were 9/10 allele matched. Seventy percent of donors had KIR B/x genotype; the others had KIR A/A genotype. NHL patients receiving 10/10 HLA-matched URD grafts with KIR B/x donors experienced significantly lower relapse at 5 years (26%; 95% confidence interval [CI], 21% to 32% versus 37%; 95% CI, 27% to 46%; P = .05) compared with KIR A/A donors, resulting in improved 5-year progression-free survival (PFS) (35%; 95% CI, 26% to 44% versus 22%; 95% CI, 11% to 35%; P = .007). In multivariate analysis, use of KIR B/x donors was associated with significantly reduced relapse risk (relative risk [RR], .63, P = .02) and improved PFS (RR, .71, P = .008). The relapse protection afforded by KIR B/x donors was not observed in HLA-mismatched transplantations and was not specific to any particular KIR-B gene. Selecting 10/10 HLA-matched and KIR B/x donors should benefit patients with NHL receiving URD allogeneic transplantation
Methods of Monitoring Training Loads in Junior Tennis Players
High training volumes and injury risk with junior tennis players has gained much attention. In recent years, the ideas of monitoring training volume to provide guidance to coaches has been an area of interest to support the potential reduction in injury rates. In tennis several internal and external methods have been used to determine training loads. Often these methods vary in cost, ease, accuracy and reliability. As such this review provides information on training monitoring for junior tennis players using methods including heart rate (HR), heart rate variability (HRV), wellness questionnaires, rating of perceived exertion (RPE), global positioning systems (GPS), physical testing and wearable technologies
Magnesia-Based Cements: A Journey of 150 Years, and Cements for the Future?
This review examines the detailed chemical insights that have been generated through 150 years of work worldwide on magnesium-based inorganic cements, with a focus on both scientific and patent literature. Magnesium carbonate, phosphate, silicate-hydrate, and oxysalt (both chloride and sulfate) cements are all assessed. Many such cements are ideally suited to specialist applications in precast construction, road repair, and other fields including nuclear waste immobilization. The majority of MgO-based cements are more costly to produce than Portland cement because of the relatively high cost of reactive sources of MgO and do not have a sufficiently high internal pH to passivate mild steel reinforcing bars. This precludes MgO-based cements from providing a large-scale replacement for Portland cement in the production of steel-reinforced concretes for civil engineering applications, despite the potential for CO2 emissions reductions offered by some such systems. Nonetheless, in uses that do not require steel reinforcement, and in locations where the MgO can be sourced at a competitive price, a detailed understanding of these systems enables their specification, design, and selection as advanced engineering materials with a strongly defined chemical basis
Precipitation of Phosphate Minerals by Microorganisms Isolated from a Fixed-Biofilm Reactor Used for the Treatment of Domestic Wastewater
The ability of bacteria isolated from a fixed-film bioreactor to precipitate phosphate crystals for the treatment of domestic wastewater in both artificial and natural media was studied. When this was demonstrated in artificial solid media for crystal formation, precipitation took place rapidly, and crystal formation began 3 days after inoculation. The percentage of phosphate-forming bacteria was slightly higher than 75%. Twelve major colonies with phosphate precipitation capacity were the dominant heterotrophic platable bacteria growing aerobically in artificial media. According to their taxonomic affiliations (based on partial sequencing of the 16S rRNA), the 12 strains belonged to the following genera of Gram-negative bacteria: Rhodobacter, Pseudoxanthobacter, Escherichia, Alcaligenes, Roseobacter, Ochrobactrum, Agromyce, Sphingomonas and Paracoccus. The phylogenetic tree shows that most of the identified populations were evolutionarily related to the Alphaproteobacteria (91.66% of sequences). The minerals formed were studied by X-ray diffraction, scanning electron microscopy (SEM), and energy dispersive X-ray microanalysis (EDX). All of these strains formed phosphate crystals and precipitated struvite (MgNH4PO4·6H2O), bobierrite [Mg3(PO4)2·8H2O] and baricite [(MgFe)3(PO4)2·8H2O]. The results obtained in this study show that struvite and spherulite crystals did not show any cell marks. Moreover, phosphate precipitation was observed in the bacterial mass but also near the colonies. Our results suggest that the microbial population contributed to phosphate precipitation by changing the media as a consequence of their metabolic activity. Moreover, the results of this research suggest that bacteria play an active role in the mineral precipitation of soluble phosphate from urban wastewater in submerged fixed-film bioreactors.This investigation was funded by the CTM 2009-11929-CO2-02 of the Spanish Ministerio de
Educación y Ciencia
Nanoparticles in cigarette smoke; real-time undiluted measurements by a scanning mobility particle sizer
Cigarette smoke is a complex mixture of smoke constituents, often characterised by size-resolved particle distributions. Since descriptions of ultrafine particles <50 nm are absent, our aim was to explore the existence of these nanoparticles in fresh and undiluted cigarette smoke. We measured undiluted smoke particles real-time by a scanning mobility particle sizer with Faraday cup electrometer, integrated in our custom-made smoking machine. Cigarettes were smoked by 2 s puffs, 30 s puff intervals and 50 ml puff volume. We tested six different cigarettes (1–10 mg tar per cigarette) at ten particle size-ranges between 6 and 50 nm, and repeated measurements five times. The formation of nanoparticles in fresh cigarette smoke was observed over the entire range between 6 and 50 nm, and reproduced in all cigarettes. The highest mean yield was 8.8 × 109 (SD = 1.1 × 109) particles per cigarette at the largest particle size range by high-tar cigarettes. Nanoparticle counts appear to increase with particle size, claimed tar values and blocking of filter ventilation holes, and inversely with butt length. Fresh undiluted cigarette smoke contains large amounts of potentially toxic nanoparticles <50 nm. We recommend to further study nanoparticles in the characterisation of cigarette smoke
Hazardous Compounds in Tobacco Smoke
Tobacco smoke is a toxic and carcinogenic mixture of more than 5,000 chemicals. The present article provides a list of 98 hazardous smoke components, based on an extensive literature search for known smoke components and their human health inhalation risks. An electronic database of smoke components containing more than 2,200 entries was generated. Emission levels in mainstream smoke have been found for 542 of the components and a human inhalation risk value for 98 components. As components with potential carcinogenic, cardiovascular and respiratory effects have been included, the three major smoke-related causes of death are all covered by the list. Given that the currently used Hoffmann list of hazardous smoke components is based on data from the 1990s and only includes carcinogens, it is recommended that the current list of 98 hazardous components is used for regulatory purposes instead. To enable risk assessment of components not covered by this list, thresholds of toxicological concern (TTC) have been established from the inhalation risk values found: 0.0018 μg day−1 for all risks, and 1.2 μg day−1 for all risks excluding carcinogenicity, the latter being similar to previously reported inhalation TTCs
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