40 research outputs found

    Personas in uniform: police officers as users of information technology

    Get PDF
    This paper apply personas to explore and analyze the highly regulated and (seemingly) uniform work practice of police officers. Historically, many information systems and information technology applications for the police has failed to meet the requirements of officers working in the field. It is claimed that a richer understanding of the practice outside the police station can result in more successful implementations of information systems for the police. An analysis of police practice is conducted through four personas of officers. The personas are derived through an analysis of an extensive set of qualitative data data from both police experience, and from observations and interviews. The personas are then situated in scenarios to visualize information related problems in the practice. The paper conclude that persona is a useful technique to analyze police work for design purpose

    Adenylate kinase activity in various organs and tissues of mice with the obese-hyperglycemic syndrome (gene symbol Ob/Ob).

    Full text link
    The activities of adenylate kinase (ATP:AMP phosphotransferase, EC 2.7.4.3) in lyophilized cryostat sections of various organs from mice with the obese-hyperglycemic syndrome (gene symbol ob/ob) were measured fluorometrically. Skeletal and heart muscle tissues had the highest enzyme activities, i.e. 258 and 155 mmoles substrate converted per kg dry weight and per hr (MKH), respectively. Pancreatic islet specimens, which were composed mainly of B-cells, possessed the highest activitty of all parenchymatous cells studied, with 18 MKH as compared to 16 MKH for the cortical tubules of the kidney and 7 and 6 for the exocrine pancreas and liver cells, respectively. The granular layer of the cerebellum had enzyme activity of 31 MKH. The adenylate kinase activity in the B-cells was apparently not influenced by hyperglycemia since it was similar both in obese-hyperglycemic mice of different ages and in lean mice, although the blood sugar concentrations in such animals are much different. </jats:p

    AN APPROACH TO THE QUANTITATIVE HISTOCHEMISTRY OF THE A-CELLS IN THE PANCREATIC ISLETS

    Full text link
    Our present knowledge of the quantitative histochemistry of the pancreas is mainly related to the enzymatic properties of the exocrine parenchyma and the B-cells. Appropriate analyses of A-cells require their isolations, which can be accomplished in animals with different islet cells located in separate groups. In fresh frozen sections of the pancreas from ducks groups of A- and B-cells were recognized by darkfield microscopy combined with ordinary microscopic examination after fixation and staining. Each adjacent section was lyophilized and separate samples of acini, A-and B-cells were dissected by free hand. Using quantitative microchemical techniques malic dehydrogenase, lactic dehydrogenase and glutamic-oxaloacetic transaminase activities were measured. The enzymatic distribution found between samples of B-cells and acini was in accordance with earlier findings in mammals, as B-cells showed higher activities except for lactic dehydrogenase. The A-cells differed from the B-cells by lower activities of malic dehydrogenase and glutamic-oxaloacetic transaminase and from the acini by lower activities of lactic dehydrogenase. </jats:p

    An improved quantitative method for the study of fibrinolysis in the skin as exemplified in patients with leukocytoclastic vasculitis and erysipelas

    Full text link
    The activity of plasminogen activator has been measured in tissue sections with the aid of a modified Todd technique. Frozen skin biopsies were sectioned and the tissue covered with fibrin-plasminogen film. After incubation at 37 degrees C fibrinolysis was studied for a period of 30 min and was graded into six exponentially increasing steps. During this period, grades were linear with the llogarithm of time of incubation. The rate of fibrinolysis is a measure of the activity of the plasminogen activator and is expressed by the slope of the linear regression of grades versus the ogarithm of time; the value of the slope is proportional to the common logarithm of the activity of the plasminogen activator present in the section. Using urokinase as a specific plasminogen activator, the same linear expression was shown with time, indicating the validity of our grading and experimental system. Eleven healthy subjects served as controls to 6 patients with leukocytoclastic vasculitis and 4 patients with erysipelas and 4 with necrotizing fascilitis. The controls showed values similar to the non-involved skin in the patients. The activity was higher in the arm than in the thigh sites. The activity in the thighs was lower in women than in men. A decrease in the plasminogen activator activity was found in the three disorders.</jats:p

    Iris conference health check traditions, tensions, and reformations

    No full text
    Regional conferences support researchers to network in a cost-efficient way. Quite often, such conferences become tight communities where friends and colleagues meet and share ideas regularly, year after year. However, with increasing public interest towards universities and the ideology of private-public management, deans and other managers have started to urge for high-quality scientific impact. Under the circumstances, regional conferences, with limited publication opportunities and lesser worldwide visibility among academics, have begun to lose their status as an important venue for science and net-working. It is equally easy and cheap to travel and attend more prestigious venues. In this paper, we analyze the main conference of the Scandinavian Chapter of the Association for Information Systems (AIS), aka IRIS association, namely IRIS, Information Systems Research Seminar in Scandinavia. We aim to understand what makes regional conferences (and chapters) sustainable. Our argumentation is based on two empirical studies; an analysis of the IRIS participants between 2011-2019 and a survey among senior scholars in the region.</p
    corecore