Déry Tibor: Összegyüjtött levelek = Tibor Déry: Collected Letters

A pályázat célja a Déry Tiborhoz és Déry Tibor által írt levelek összegyűjtése és kiadásra való előkészítése volt. A pályázó hét egységbe rendezte az író hagyatékában és más közintézményekben található kb. 8000 ezernyi levelet, és megkezdte kommentárokkal ellátott szerkesztésüket. 2004 és 2007 között sikerült három kötetben megjelentetni az 1901 és 1945 közötti időszak 859 levelét, és nyomdakész állapoba hozni a második egység /1945-1960/ anyagát valamint kiszedetni a harmadik egység /1960-1963/szövegeit. A sorozatot a Petőfi Irodalmi Múzeum és a Balassi Kiadó jelenteti meg, kötetenként 350-400 oldal terjedelemben, a levélírók írásmintáival, a levelezőlapok és a kötetekben szereplő könyvek és folyóiratok címlapjainak színes reprodukcióival. | Tibor Déry: Collected letters research report The research proposal aimed at collecting and publishing the letters written to and by Tibor Déry. The letters have been collected from Déry?s heritage found in the Petőfi Literary Museum and in other archives (about 8000 letters altogether). They have been arranged in 7 units and the the edition of the texts has begun. Between 2004 and 2007 texts of the first unit (859 letters from the period 1901-1945) were published, the edition of the second unit (1945-1960) was completed, and the manuscripts of the third unit (1960-1963) were set up. The series is jointly published by Petőfi Literary Museum and Balassi Publishing House. Besides the texts, the editions contain reproductions of the manuscripts, postcards as well as the original book covers

Beremendia (Mammalia, Soricidae) remains from the late Early Pleistocene Somssich Hill 2 locality (Southern Hungary) and their taxonomic, biostratigraphical, palaeoecological and palaeobiogeographical relations

Beremendia fi ssidens and B. minor remains of the late Early Pleistocene vertebrate fauna of the Somssich Hill 2 locality are described. B. minor is reported here as a new element in the site. This record emended the stratigraphic range of this species to the Early Biharian Stage, Nagyharsányhegy Phase (ca. 900 ka). The detailed morphological and morphometrical studies gave a chance to make a new diff erential diagnosis between the two forms. Both of them might have been characterized by special nutrition strategy (poisoning snails and other small animals by their grooved lower incisor and storing them in their pits) and they could have lived in forest- and bushcovered lake-, or riversides. The European stratigraphical and palaeobiogeographical occurrences of the genus are summarized on the basis of published literature

A Somssich-hegy 2-es lelőhely (Villányi-hegység) alsó-pleisztocén Beremendia fissidens (Mammalia, Soricidae) maradványainak taxonómiai és paleoökológiai vizsgálata

A cikk a Somssich-hegy 2-es lelőhely Beremendia fissidens cickánymaradványainak részletes anatómiai és taxonó - miai leírását mutatja be. Az Osztramos 7-es lelőhely anyagával való összevetés lehetővé tette a pontos elkülönítő diagnózis kidolgozását a rokonfaj B. minortól. A lelőhelyen feltárt 50 rétegből 169 maradványt sikerült azonosítani, 61 minimum egyedszámmal. A nagy egyedszám lehetőséget biztosított a fogak méreteinek pontosabb meghatározására. A faj legtöbb rétegben azonosítható jelenléte a lelőhely közelében nyílt víztükör jelenlétére utal. Ebben az ökotópban a Beremendia különleges táplálkozási stratégiát folytatott, amely nagyban segítette túlélését. Hasított metszőfoga segítségével mérget juttathatott prédájába. A megbénított áldozatok raktározása lehetőséget nyújtott a kedvezőtlen időszakok átvészelésére

Beremendia (Mammalia, Soricidae) remains from the late Early Pleistocene Somssich Hill 2 locality (Southern Hungary) and their taxonomic, biostratigraphic, palaeoecological and palaeobiogeographical relations

Beremendia fi ssidens and B. minor remains of the late Early Pleistocene vertebrate fauna of the Somssich Hill 2 locality are described. B. minor is reported here as a new element in the site. This record emended the stratigraphic range of this species to the Early Biharian Stage, Nagyharsányhegy Phase (ca. 900 ka). The detailed morphological and morphometrical studies gave a chance to make a new diff erential diagnosis between the two forms. Both of them might have been characterized by special nutrition strategy (poisoning snails and other small animals by their grooved lower incisor and storing them in their pits) and they could have lived in forest- and bushcovered lake-, or riversides. The European stratigraphical and palaeobiogeographical occurrences of the genus are summarized on the basis of published literature

Campylobacter jejuni Type VI Secretion System: Roles in Adaptation to Deoxycholic Acid, Host Cell Adherence, Invasion, and In Vivo Colonization

The recently identified type VI secretion system (T6SS) of proteobacteria has been shown to promote pathogenicity, competitive advantage over competing microorganisms, and adaptation to environmental perturbation. By detailed phenotypic characterization of loss-of-function mutants, in silico, in vitro and in vivo analyses, we provide evidence that the enteric pathogen, Campylobacter jejuni, possesses a functional T6SS and that the secretion system exerts pleiotropic effects on two crucial processes – survival in a bile salt, deoxycholic acid (DCA), and host cell adherence and invasion. The expression of T6SS during initial exposure to the upper range of physiological levels of DCA (0.075%–0.2%) was detrimental to C. jejuni proliferation, whereas down-regulation or inactivation of T6SS enabled C. jejuni to resist this effect. The C. jejuni multidrug efflux transporter gene, cmeA, was significantly up-regulated during the initial exposure to DCA in the wild type C. jejuni relative to the T6SS-deficient strains, suggesting that inhibition of proliferation is the consequence of T6SS-mediated DCA influx. A sequential modulation of the efflux transporter activity and the T6SS represents, in part, an adaptive mechanism for C. jejuni to overcome this inhibitory effect, thereby ensuring its survival. C. jejuni T6SS plays important roles in host cell adhesion and invasion as T6SS inactivation resulted in a reduction of adherence to and invasion of in vitro cell lines, while over-expression of a hemolysin co-regulated protein, which encodes a secreted T6SS component, greatly enhanced these processes. When inoculated into B6.129P2-IL-10[superscript tm1Cgn] mice, the T6SS-deficient C. jejuni strains did not effectively establish persistent colonization, indicating that T6SS contributes to colonization in vivo. Taken together, our data demonstrate the importance of bacterial T6SS in host cell adhesion, invasion, colonization and, for the first time to our knowledge, adaptation to DCA, providing new insights into the role of T6SS in C. jejuni pathogenesis

Djelovanje N-fenil-izopropil-karbamata na strukturu i fotosintetsku aktivnost etiokloroplasta

The effect of isopropyl N-phenylcarbamate (IPC) on the development of the structure and function of etiochloroplasts in greening bean leaves has been studied by pigment analysis, measurements of photosynthetic activity and ultrastructural analysis. The investigations have shown that IPC strongly inhibits the development of the thylakoid system, the synthesis of the chlorophyll and the photosynthetic activity of the etiochloroplasts; cytochemical analyses indicate that the development of both photosystem I and photosystem II are partly inhibited by IPC. The experiments have shown further that the production of all new membrane structures in the etiochloroplasts is strongly affected by IPC, so that these organelles constantly remain in the early etiochloroplast stage of development. When green leaves are treated with IPC, there are no large ultra- structural changes in the chloroplasts, although the photosynthetic activity is lowered to less than a half of that of the control leaves.Istražen je utjecaj N-fenil-izopropil-karbamata (IPC) na strukturu i funkciju etiokloroplasta u listovima graha tijekom njihova ozelenjavanja. Istraženi su sastav pigmenata, fotosintetska aktivnost i ultrastruktura tretiranih i kontrolnih listova. Istraživanja su pokazala da IPC snažno inhibirá razvoj tilakoidnog aparata, sintezu klorofila i fotosintetsku aktivnost etiokloroplasta, a citokemijski nalazi upućuju na to da on djelomično inhibira i fotosistem I i fotosistem II. Pokusi pokazuju nadalje da IPC snažno inhibirá sintezu de novo svih membranskih struktura u etiokloroplastima, tako da oni zaostanu u svom ranom razvojnom stadiju. Ako se zeleni listovi graha tretiraju IPC-om, ultrastruktura njihovih kloroplasta samo je neznatno izmijenjena. Istovremeno pak njihova je fotosintetska aktivnost smanjena na manje od 50% aktivnosti kontrolnih listova

Interactions and Chemical Transformations of Coronene Inside and Outside Carbon Nanotubes

By exposing flat and curved carbon surfaces to coronene, a variety of van der Waals hybrid heterostructures were prepared, including coronene encapsulated in carbon nanotubes, and coronene and dicoronylene adsorbed on nanotubes or graphite via π – π interactions. The structure of the final product is determined by the temperature of the experiment and the curvature of the carbon surface. While at temperatures below and close to the sublimation point of coronene, nanotubes with suitable diameters are filled with single coronene molecules, at higher temperatures additional dimerization and oligomerization of coronene occurs on the surface of carbon nanotubes. The fact that dicoronylene and possible higher oligomers are formed at lower temperatures than expected for vapor-phase polymerization indicates the active role of the carbon surface used primarily as template. Removal of adsorbed species from the nanotube surface is of utmost importance for reliable characterization of encapsulated molecules: it is demonstrated that the green fluorescence attributed previously to encapsulated coronene is instead caused by dicoronylene adsorbed on the surface which can be solubilized and removed using surfactants. After removing most of the adsorbed layer, a combination of Raman spectroscopy and transmission electron microscopy was employed to follow the transformation dynamics of coronene molecules inside nanotubes