Dog sensitization and allergy to mites: do they respond the same way to poultry red mite as to house-dust and storage mites?

Background Dermanyssus gallinae, the European poultry red mite (PRM), is a common ectoparasite of laying chickens and pigeons but can also feed on other birds, humans and domestic animals, causing from mild discomfort to severe dermatitis, with possible transmission of several infectious agents. In affected dogs clinical signs resembling flea allergy were reported, but very little is known about either a possible type I hypersensitivity to PRM in dogs or an eventual cross-sensitization with house-dust or storage mites. Investigating on IgE-mediated allergy to PRM in dogs is important from both veterinary and human health perspectives as knowledge about an IgE-mediated allergy in humans and their dogs, and possible cross-sensitization with dust and storage mites will favor a better clinical approach. Our aim was to clarify i) whether there is evidence of type I hypersensitivity to PRM in dogs, by testing for specific IgE to PRM and ii) the possible occurrence of cross-sensitization with dust and storage mites. Method Sixteen dogs with long-lasting close contact with chickens from traditional bird houses and 5 control dogs from an allergy outpatient consultation, with no direct contact with birds, were subjected to commercial intradermal tests for the most common dust and storage mites (Diater, Spain) and with D. gallinae extract (LETI, Spain) in four concentrations (1, 0.5, 0.1 and 0.01 mg/mL). Serum specific IgE (sIgE) to PRM was determined by ELISA at LETI Animal Health Laboratories (Spain). Results Three control dogs presented positive IDT to PRM and 2 were negative, each of them to every concentration. IDT were found positive in 10 chicken-contacting dogs with 0.1 mg and in only 6 with 0.01 mg/mL. IDT response to PRM was found gradual between 0.1 and 0.01 mg/mL of extract concentration. Serum sIgE to PRM was detected in 1 control (20%) and in 7 (44%) chicken-contacting dogs. No significant correlation was found between PRM and dust and storage mites IDT and between IDT and sIgE to PRM. Conclusion The adequate PRM IDT extract concentration could be in the 0.1-0.01 mg/mL range. Close contact with infested chickens, hence with PRM may conduce to a possible state of sensitization with detectable sIgE without allergy, necessarily. Sensitization and allergy to PRM may be independent from their equivalent to dust and storage mites

Simulation of On-Board Supercapacitor Energy Storage System for Tatra T3A Type Tramcars

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Stent fracture after endovascular treatment patient with subclavian vein thrombosis – difficult diagnosis and complication of venous thoracic outlet syndrome

Subclavian vein thrombosis is relatively rare. It constitutes 4 to 10% of all cases of venous thrombosis and is often associated with compression or canniulation of the subclavian vein. We present the case of patient with Paget-Schroetter syndrome treated in our center for right subclavian vein thrombosis as a result of the venous thoracic outlet syndrome (VTOS). In the case described below, VTOS was unrecognized and the stent fracture following endovascular treatment led to a relapse of venous thrombosis. Secondary angioplasty and stenting with subclavian vein decompression was successfully made. The patient was regularly monitored throughout the following year and there was no relapse of clinical symptoms. Conclusions: in case of subclavian vein thrombosis decompression is a very important step in the management of VTOS. It prevents recurrence of thrombosis and potential complications

Skeletopic analysis of the gonadal veins in human foetuses

During ontogenesis an imbalance is observable in the development of the skeletal and vascular systems. By means of anatomical and radiological methods the gonadal veins were studied in relation to the vertebral column in 60 human foetuses of both sexes aged from 4 to 6 months of prenatal life. In male foetuses aged 4–5 months the origin of the gonadal veins projected onto the sacral apex (r1 = 0.95, r3 = 0.85), and in 6th month they extended below the vertebral column (r1’ = 0.80, r3’ = 0.90). In female foetuses the origin of the gonadal veins in the 4th month projected symmetrically onto S1 (r5 = 0.70, r7 = 0.70). In the 5th month of intrauterine life the origin of the left ovarian vein was found at S2 (r7’ = 0.80) and the origin of the right one at S1–S2 (r5’ = 0.80). In the 6th month the origin of the left ovarian vein was located at S3 (r7’ = 0.80) and the right one at S2–S3 (r5’’ = 0.90). The skeletopic analysis of the origin of the gonadal veins demonstrated gender (the origin was higher in females) and syntopic (the origin was higher on the right side) differences (p ≤ 0.05). In foetuses of both sexes aged 4 months of prenatal life the termination of the left gonadal veins projected onto Th12–L1 (r4 = 0.85, r8 = 0.80) and in foetuses aged 5–6 months it projected onto L1–L2 (r4’ = 0.90, r8’ = 0.95). In both sexes the termination of the gonadal veins on the right side projected constantly onto L2 (r2 = 0.90, r6 = 0.95) from the 4th to the 6th month of intrauterine life. The skeletopic analysis of the termination of the gonadal veins showed syntopic dimorphism (p ≤ 0.05) without gender differences (p > 0.05). On the right side the termination of the gonadal (testicular and ovarian) veins projected constantly onto L2. On the left side the termination of the left gonadal (testicular and ovarian) veins apparently descended by one vertebra (pseudodescensus)

Simulations of mid infrared emission of InAsN semiconductors

This paper delivers an approximation to the complex many body problem of luminescence in semiconductors to the case of mid infrared luminescence of dilute nitrides. The results are compared with recent experimental data for InAsN semiconductors