ANALISIS KEMAMPUAN PEMECAHAN MASALAH MATEMATIK MATERI LINGKARAN SISWA SMP BERDASARKAN GENDER

The purpose of this study was to analyze the problem solving skills of junior high school students based on student gender. This research is descriptive qualitative. Data from the research results obtained from the results of writing written questions and the results of oral interviews of 14 students of class VIII from Waringin Middle School, Bandung. The instrument used is 3 numbers of material questions that are in accordance with indicators of cognitive aspects. The results of this study indicate that from the problem description given and from the results of interviews about problem solving abilities of junior high school students with female gender on average, it is better than the problem solving ability on average junior high school students have a way to solve while solving problems. So that researchers can conduct research using active student learning methods to get better results, and also be able to understand other factors related to problem solving problems of junior high school students, both male and female students

ANALISIS KEMAMPUAN PEMECAHAN MASALAH MATEMATIS SISWA SMP DITINJAU DARI HEURISTIK SISWA

Kemampuan pemecahan masalah adalah kemampuan siswa untuk menyelesaikan masalah yang tidak rutin dengan menggunakan pengetahuan dan pola pikir yang mendasar (Ruseffendi, 2006) . Proses pemecahan masalah dapat dilihat sebagai suatu heuristik, yaitu sebagai proses deduksi solusi dari pengetahuan yang sudah ada sebelumnya. Kemampuan pemecahan masalah sangat dipengaruhi oleh pengetahuan siswa sebelumnya yang mempengaruhi pemahaman masalah dan pemilihan strategi yang akan digunakan dalam mencoba untuk menyelesaikan masalah tersebut. Penelitian ini adalah penelitian kualitatif dengan pendekatan deskriptif kualitatif yang bertujuan untuk mengevaluasi kemampuan pemecahan masalah matematis dari heuristik siswa. Dari hasil tes yang telah diberikan terbukti bahwa heuristik siswa sangat membantu siswa dalam mengerjakan soal pemecahan masalah matematis non-rutin. Hal tersebut dibuktikan dengan sedikitnya jumlah jawaban yang tidak diisi dibandingkan soal yang terisi. Selain itu juga dibuktikan dari persentase jumlah soal yang dijawab benar oleh siswa yaitu 74 %, sedangkan hanya 26% dari total soal yang dikerjakan siswa dijawab dengan salah maupun tidak diisi. Berdasarkan hasil penelitian analisis kemampuan pemecahan masalah siswa didasarkan heuristik siswa, guru sebaiknya terus melaksanakan pembelajaran yang melatih kemampuan heuristik siswanya, dengan cara selalu menyisipkan soal soal non rutin dalam pembelajaran. Selain itu juga guru perlu membebaskan siswa untuk sekreatif mungking dalam menjawab soal pemecahan masalah, karena dengan cara itulah siswa mengeluarkan kemampuan heuristiknya

HUBUNGAN STRES KERJA DENGAN PERILAKU PRESENTEEISM PERAWAT RUMAH SAKIT X MAKASSAR

Nurse is a job susceptible to occupational stress for timing pressure and high burden of workload. Occupational stress of nurses could force them into presenteeism behavior, the condition when employee push themself to still working although not in good and healthy condition. The aim of this study was to find correlation between occupational stresses with nurses presenteeism. Samples of this study were 50 nurses of inpatient room of X Hospital in Makassar which taken by using total sampling method. Measuring instruments used in this study were nurses job stress scale (α = 0,859) and presenteeism scale (α = 0,816). Using hypothetical test of Spearman correlation, results found r = 0,653 and p = < 0,05. The result means there was positive correlation between occupational stresses with nurses presenteeism on X Hospital in Makassar. Presenteeism can affect the productivity of nurses, so it is important for hospitals to control the nurses occupational stress to reduce the appearance of presenteeism and avoid the negative impact of presenteeism.Perawat merupakan profesi yang rentan mengalami stres kerja akibat tekanan waktu dan beban kerja yang tinggi. Stres kerja yang dialami oleh perawat dapat mendorong pada perilaku presenteeism, yaitu kondisi ketika karyawan tetap memaksakan diri untuk hadir bekerja meskipun dalam kondisi yang tidak sehat. Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara stres kerja dengan perilaku presenteeism perawat. Responden pada penelitian sebanyak 50 orang perawat di ruang rawat inap Rumah Sakit X Makassar yang diambil dengan metode total sampling. Alat ukur yang digunakan dalam penelitian ini adalah skala stres kerja perawat (α = 0,859) dan skala presenteeism (α = 0,816). Berdasarkan uji hipotesis dengan menggunakan korelasi spearman diperoleh nilai r = 0,653 dan nilai p < 0,05. Hasil ini menunjukkan bahwa ada hubungan positif antara stres kerja dengan perilaku presenteeism perawat di RS. X Makassar. Presenteeism dapat memengaruhi produktivitas kerja perawat, sehingga sangat penting bagi rumah sakit untuk mengotrol stres kerja perawat untuk mengurangi munculnya perilaku  presenteeism dan menghindari dampak negatif dari perilaku presenteeism

Tanggapan Masyarakat Pantai Licin sebagai Daerah Tujuan Wisata di Desa Lebakharjo Kecamatan Ampelgading, Malang

Abstrak: Sektor pariwisata Provinsi Jawa Timur merupakan salah satu andalan untuk meningkatkan perekonomian. Provinsi Jawa Timur mulai mencoba memperkenalkan progam Visit East Java untuk memperkenalkan objek wisata yang berada di Jawa Timur. Kabupaten Malang merupakan salah satu kabupaten yang mengikuti program Visit East. Pantai Licin termasuk dalam kategori pantai yang akan dikembangkan oleh pemerintah kabupaten. Penelitian ini bermanfaat untuk (1) informasi untuk mendukung perencanaan pengembangan objek wisata Pantai Licin (2) informasi tentang adanya potensi pantai yang belum dikembangkan dan diharapkan adanya partisipasi masyarakat dalam mendukung pengembangan objek wisata Pantai Licin. Jenis penelitian ini adalah survei. Subyek penelitian ini adalah masyarakat Pantai Licin. Data tanggapan digunakan untuk mengetahui kesiapan masyarakat apabila Pantai Licin dijadikan sebagai objek wisata. Populasi penelitian sebanyak 30 orang. Analisis data menggunakan statistik deskriptif, yaitu scoring dan tabulasi. Berdasarkan hasil analisis, diperoleh kondisi non-fisik yang meliputi tanggapan masyarakat tergolong setuju apabila Pantai Licin dijadikan sebagai objek wisata.   DOI: http://dx.doi.org/10.17977/um017v21i22016p00

TANGGAPAN MASYARAKAT PANTAI LICIN SEBAGAI DAERAH TUJUAN WISATA DI DESA LEBAKHARJO KECAMATAN AMPELGADING, MALANG

Abstrak: Sektor pariwisata Provinsi Jawa Timur merupakan salah satu andalan untuk meningkatkan perekonomian. Provinsi Jawa Timur mulai mencoba memperkenalkan progam Visit East Java untuk memperkenalkan objek wisata yang berada di Jawa Timur. Kabupaten Malang merupakan salah satu kabupaten yang mengikuti program Visit East. Pantai Licin termasuk dalam kategori pantai yang akan dikembangkan oleh pemerintah kabupaten. Penelitian ini bermanfaat untuk (1) informasi untuk mendukung perencanaan pengembangan objek wisata Pantai Licin (2) informasi tentang adanya potensi pantai yang belum dikembangkan dan diharapkan adanya partisipasi masyarakat dalam mendukung pengembangan objek wisata Pantai Licin. Jenis penelitian ini adalah survei. Subyek penelitian ini adalah masyarakat Pantai Licin. Data tanggapan digunakan untuk mengetahui kesiapan masyarakat apabila Pantai Licin dijadikan sebagai objek wisata. Populasi penelitian sebanyak 30 orang. Analisis data menggunakan statistik deskriptif, yaitu scoring dan tabulasi. Berdasarkan hasil analisis, diperoleh kondisi non-fisik yang meliputi tanggapan masyarakat tergolong setuju apabila Pantai Licin dijadikan sebagai objek wisata.Kata Kunci: Tanggapan, Pantai Licin

Pengaruh Pemberian Nutrisi Phaseolus radiatus L. Terhadap Tingkat Kepadatan Spermatozoa Mus musculus L.

Research about the effect of greenpeal sprout Phaseolus radiatus L. on the spermatozoa density of Mus musculus L. has been done. The purpose of this research was to know the effect of greenpeal sprout Phaseolus radiatus L. on the spermatozoa density of Mus musculus L. Mice is feeded with greenpeal sprout for 21 days. The sperm is collected from cauda of epididimis diluted physiological solution and counted using haemocytometer. The result showed that micefeeding with greenpeal sprout could increase the density of its spermatozoa. It showed from increase the density of its spermatozoa from 11,05 million/cc sperm in control group become 11,78 million/cc sperm in treatment group by use of T test. Fidelity guarantee 95 percent explain that there are positive correlation and significant. Keywords: Greenpeal sprout, Mus musculus L., Phaseolus radiatus L., Spermatozo

A model for predicting bacteremia species based on host immune response

IntroductionClinicians encounter significant challenges in quickly and accurately identifying the bacterial species responsible for patient bacteremia and in selecting appropriate antibiotics for timely treatment. This study introduces a novel approach that combines immune response data from routine blood counts with assessments of immune cell activation, specifically through quantitative measurements of Rho family GTPase activity. The combined data were used to develop a machine-learning model capable of distinguishing specific classes of bacteria and their associations.MethodsWe aimed to determine whether different classes of bacteria elicit distinct patterns of host immune responses, as indicated by quantitative differences in leukocyte populations from routine complete blood counts with differential. Concurrently, we conducted quantitative measurements of activated Rac1 (Rac1•GTP) levels using a novel ‘G-Trap assay’ we developed. With the G-Trap, we measured Rac1•GTP in peripheral blood monocytes (PBMC) and polymorphonuclear (PMN) cells from blood samples collected from 28 culture-positive patients and over 80 non-infected patients used as controls.ResultsOur findings indicated that 18 of the 28 patients with bacteremia showed an increase of ≥ 3-fold in Rac1•GTP levels compared to the controls. The remaining ten patients with bacteremia exhibited either neutrophilia or pancytopenia and displayed normal to below-normal Rac1 GTPase activity, which is consistent with bacteria-induced immunosuppression. To analyze the data, we employed partial least squares discriminant analysis (PLS-DA), a supervised method that optimizes group separation and aids in building a novel machine-learning model for pathogen identification.DiscussionThe results demonstrated that PLS-DA effectively differentiates between specific pathogen groups, and external validation confirmed the predictive model's utility. Given that bacterial culture confirmation may take several days, our study underscores the potential of combining routine assays with a machine-learning model as a valuable clinical decision-support tool. This approach could enable prompt and accurate treatment on the same day that patients present to the clinic

Fluorescence biosensing strategy based on energy transfer between fluorescently labeled receptors and a metallic surface

A new fluorescence-based biosensor is presented. The biosensing scheme is based on the fact that a fluorophore in close proximity to a metal film (100 Å) experiences strong quenching of fluorescence and a dramatic reduction in the lifetime of the excited state. By immobilizing the analyte of interest (or a structural analog of the analyte) to a metal surface and exposing it to a labeled receptor (e.g. antibody), the fluorescence of the labeled receptor becomes quenched upon binding because of the close proximity to the metal. Upon exposure to free analyte, the labeled receptor dissociates from the surface and diffuses into the bulk of the solution. This increases its separation from the metal and an increase of fluorescence intensity and/or lifetime of the excited state is observed that indicates the presence of the soluble analyte. By enclosing this system within a small volume with a semipermeable membrane, a reversible device is obtained. We demonstrate this scheme using a biotinylated self-assembled monolayer (SAM) on gold as our surface immobilized analyte analog, fluorescently labeled anti-biotin as a receptor, and a solution of biotin in PBS as a model analyte. This scheme could easily be extended to transduce a wide variety of protein–ligand interactions and other biorecognition phenomena (e.g. DNA hybridization) that result in changes in the architecture of surface immobilized biomolecules such that a change in the separation distance between fluorophores and the metal film is obtained.Postprintapplication/pdfPérez-Luna, V. H., Yang S., Rabinovich, E. M., Buranda, T., Sklar, L. A., Hampton, P. D., Lopez, G. P. (2002). Fluorescence biosensing strategy based on energy transfer between fluorescently labeled receptors and a metallic surface. Biosensors and Bioelectronics v. 17 no. 1/2 p. 71-780956-566

Characterization of a Cdc42 Protein Inhibitor and Its Use as a Molecular Probe

Cdc42 plays important roles in cytoskeleton organization, cell cycle progression, signal transduction, and vesicle trafficking. Overactive Cdc42 has been implicated in the pathology of cancers, immune diseases, and neuronal disorders. Therefore, Cdc42 inhibitors would be useful in probing molecular pathways and could have therapeutic potential. Previous inhibitors have lacked selectivity and trended toward toxicity. We report here the characterization of a Cdc42-selective guanine nucleotide binding lead inhibitor that was identified by high throughput screening. A second active analog was identified via structure-activity relationship studies. The compounds demonstrated excellent selectivity with no inhibition toward Rho and Rac in the same GTPase family. Biochemical characterization showed that the compounds act as noncompetitive allosteric inhibitors. When tested in cellular assays, the lead compound inhibited Cdc42-related filopodia formation and cell migration. The lead compound was also used to clarify the involvement of Cdc42 in the Sin Nombre virus internalization and the signaling pathway of integrin VLA-4. Together, these data present the characterization of a novel Cdc42-selective allosteric inhibitor and a related analog, the use of which will facilitate drug development targeting Cdc42-related diseases and molecular pathway studies that involve GTPases.This work was supported by National Science Foundation (NSF) Grant MCB0956027 and National Institutes of Health Grant R03 MH081231-01 from the Molecular Libraries Program (to A. W. N.); University of New Mexico Center for Molecular Discovery Molecular Libraries Probe Production Centers (UNMCMD MLPCN) National Institutes of Health Grants U54MH084690 and R01HL081062 (to L. A. S.); UNM National Center for Research Resources (NCRR) Grant 5P20RR016480 (to L. G. H.); National Institutes of Health Grant R21 CA170375-01 through the NCI (to A. W. N., L. G. H., and J. E. G.); National Institutes of Health Grants NS066429 and AI092130 (to T. B.); and University of Kansas Specialized Chemistry Center (KUSCC) MLPCN National Institutes of Health Grant U54HG005031 (to J. A.)