910 research outputs found

    University Scholar Series: Ted Butryn and Matthew Masucci

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    Examining Female Triathletes\u27 Awareness of Doping and the Anti-doping Movement On February 26, 2014, Dr. Ted Butryn and Dr. Matthew Masucci spoke in the University Scholar Series hosted by Interim Provost Andy Feinstein at the Dr. Martin Luther King, Jr. Library. SJSU professors Ted Butryn and Matthew Masucci co-investigated on a two-year World Anti-Doping Agency grant, which examined female triathletes and their awareness of doping and the anti-doping movement. Dr. Butryn is a 2012 Salzburg Fellow and Professor of Sport Sociology and Sport Psychology in the Department of Kinesiology. Dr. Masucci is an Associate Professor of Interdisciplinary Sport Studies in Kinesiology. Both Butryn and Masucci co-direct the Department of Kinesiology\u27s Qualitative Research Lab.https://scholarworks.sjsu.edu/uss/1031/thumbnail.jp

    Effects of Electrical Stimulation on Wound Closure in Mice with Experimental Diabetes Mellitus

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    The purpose of the present study was to examine the effect of electrical stimulation (ES) on the closure of full-thickness excisional wounds in mice with type-1 experimental diabetes mellitus (DM). Alloxon monohydrate (100mg/kg) was used to induce experimental DM in mole CD-1 mice (n = 88). Full-thickness skin excisions (1cm2) in diabetic (urine glucose \u3e 0) and non-diabetic (urine glucose = 0) mice were administered 1, 3, or 5 treatments of ES (200μs, 200 Hz) for 15 minutes, at 0 (sham), 5, 10, or 12.5 volts. Alloxon injection resulted in a positive urine glucose test in 48 mice yielding an induction rate for DM of 54.5 percent. All groups exhibited decreases in wound length, perimeter, and surface area between days 2 and 16 following the creation of wounds. Non-diabetic wounds treated with ES hod the greatest percentage (60%) of closure. Diabetic wounds treated with ES hod a greater percentage of clo­sure (36%) compared with sham-treated diabetic animals (12.5%). Treatment of wounds with the highest voltage of ES (12.5V) produced significant (P \u3c 0.01) decreases in the surface area, and significant (P \u3c 0.01) changes in the shapes of wounds in both diabetic and non-diabetic animals compared with sham-treated animals. These results support the clinical use of this adjunctive therapy to accelerate the closure of ulcers due to OM

    The whole-brain pattern of magnetic susceptibility perturbations in Parkinson's disease

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    Although iron-mediated oxidative stress has been proposed as a potential pathomechanism in Parkinson's disease, the global distribution of iron accumulation in Parkinson's disease has not yet been elucidated. This study used a new magnetic resonance imaging contrast, quantitative susceptibility mapping, and state-of-the-art methods to map for the first time the whole-brain landscape of magnetostatic alterations as a surrogate for iron level changes in n = 25 patients with idiopathic Parkinson's disease versus n = 50 matched controls. In addition to whole-brain analysis, a regional study including sub-segmentation of the substantia nigra into dorsal and ventral regions and qualitative assessment of susceptibility maps in single subjects were also performed. The most remarkable basal ganglia effect was an apparent magnetic susceptibility increase-consistent with iron deposition-in the dorsal substantia nigra, though an effect was also observed in ventral regions. Increased bulk susceptibility, additionally, was detected in rostral pontine areas and in a cortical pattern tightly concordant with known Parkinson's disease distributions of α-synuclein pathology. In contrast, the normally iron-rich cerebellar dentate nucleus returned a susceptibility reduction suggesting decreased iron content. These results are in agreement with previous post-mortem studies in which iron content was evaluated in specific regions of interest; however, extensive neocortical and cerebellar changes constitute a far more complex pattern of iron dysregulation than was anticipated. Such findings also stand in stark contrast to the lack of statistically significant group change using conventional magnetic resonance imaging methods namely voxel-based morphometry, cortical thickness analysis, subcortical volumetry and tract-based diffusion tensor analysis; confirming the potential of whole-brain quantitative susceptibility mapping as an in vivo biomarker in Parkinson's disease

    Finishing treatment of the involute surfaces og the direct gear wheels by the surfaces plastic deformation forming regular micro-projection

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    Розглянуто існуючі методи поверхневого пластичного зміцнення робочих поверхонь циліндричних прямозубих коліс. Запрпоновано метод вібраційного обкочування зубчастих колі

    Šaunamųjų ginklų prieinamumo reglamentavimas

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    The subject of this article are the legal and criminal aspects of regulating access to firearms. This issue has become extremely important in recent years for sociality. Furthermore, the availability of firearms has been widely discussed in Poland.Šio straipsnio tema yra šaunamųjų ginklų prieinamumo reglamentavimo teisiniai ir su nusikaltimais susiję aspektai. Šis klausimas pastaraisiais metais tapo ypač svarbiu socialiniu klausimu. Be to, Lenkijoje buvo plačiai diskutuojama apie šaunamųjų ginklų prieinamumą

    Posthuman podiums : the technological life-history narratives of elite track and field athletes

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    Narrative research has emerged as a powerful means of exploring athletes’ lives through the stones they tell about themselves (Duncan, 1998, Foley, 1992, McDonald & Birrell, 1999, Sparkes, 1999, 2000). In this study I examined the technological life-histories of seven elite track and field athletes using a narrative analysis (Polkinghome, 1997). As Haraway (1985) points out, the cyborg era has ushered in multiple modes of subjectivity which are best understood through narratives, the stories we tell within the context of an early 21st century technoculture. Through an analysis of in-depth interviews, observational data, personal photographs, and the application of theoretical concepts related to technology, participants\u27 stories were configured into narrative texts that represent individualized literary portraits of the ways that their lives have been technologically textured (Ihde, 1993) since childhood. The narratives presented in this study illustrate the interpenetration of athletes and technology, and trace the formation and reformation of athletic identities that are informed by and shaped through lifelong encounters with technology. Further, the texts relate to the inherent tensions within the community of Olympic-caliber track and field, in which athletes are driven to employ various technologies in their efforts to perform, yet simultaneously strictly regulated terms of what they can and cannot use by various governing agencies. The stories participants told generally indicated an appreciation of the role of technology in their sport,but a reluctance to engage with certain technologies that they felt might compromise their own sense of athletic “purity.” Thus, while they were of what I will call “hegemonic humanness,” they generally complicit in the maintenance also demonstrated varying levels of resistance that were contingent on context and their unique life experiences both within and outside of sport. Finally, I hoped that by participating in this study and helping to co-construct their narratives,these athletes would feel compelled to engage in critical dialogues with other competitors and administrators regarding the current and future role of technology in track and field, and how the decision-making process related to the use or restriction of technologies might become more democratic

    Structural characterization of the Swi2/Snf2 ATPase Mot1 in complex with protein and DNA substrate

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