The statistical analysis of spatial point patterns

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A Bulky Biaryl Phosphine Ligand Allows for Palladium-Catalyzed Amidation of Five-Membered Heterocycles as Electrophiles

The incredible bulk: The first palladium-catalyzed amidation of five-membered heterocyclic bromides with multiple heteroatoms was achieved using the Pd/1 catalyst system. N-Arylated imidazoles, pyrazoles, thiazoles, pyrroles, and thiophenes were synthesized in moderate to excellent yield. Experimental results and DFT calculations point to the need for an electron-rich and sterically demanding biaryl phosphine ligand to promote these difficult reactions.National Institutes of Health (U.S.) (Grant GM58160)National Science Foundation (U.S.) (Grant CHE9808061)National Science Foundation (U.S.) (Grant DBI 9729592)National Science Foundation (U.S.) (CHE-0946721

Reparations – An Exploration of Musical Narratives in an Australian Context

This project entailed the composition, recording and production of 8 pieces of music centred around addressing social issues in my home country of Australia through the use of musical narratives. These issues included Australia’s mistreatment of Indigenous Australians and inaction in combating environmental degradation and climate change. Throughout my research in these two areas, the intersectionality of these issues became more clear to me as I delved deeper into the history behind their manifestation in Australia. Throughout my research and composition process, I drew inspiration from a wide range of Australian artistic works including music, literature, photography and visual art, with the goal of creating an interconnected body of work that served the ultimate purpose of inspiring positive social change with regards to systemic racism and environmental degradation in Australia, as well as contributing to the global fight against these forces.https://remix.berklee.edu/graduate-studies-global-jazz/1090/thumbnail.jp

Alien Registration- Byth, Ann L. (Saco, York County)

https://digitalmaine.com/alien_docs/4100/thumbnail.jp

Phenanthrene Synthesis and the Biosynthesis of Mollisin

Mollisin (1) 4.5 is derived via the polyketide pathway in the fungus Mollisia caesia and is the only known natural product to contain an aromatic dichloroacetyl moiety. Since its discovery in 1956 several 50-54 groups have attempted to unravel the biosynthesis of mollisin because of its unique structure. The ultimate aim of the work described in this thesis was to elucidate the biogenesis of this unusual fungal metabolite and is in part a continuation of the work performed 50 by A. A. Finnie 50 in this laboratory. The Introduction gives a brief account of the polyketide pathway and discusses biological chlorination, a common in vivo modification in the biosynthesis of polyketides and other classes of metabolite. The Introduction also describes in detail the mechanism for the formation of phenanthrenes via stilbene photocyclisation. This is relevant to subsequent chapters dealing with synthetic strategies to the phenanthrene derivatives which are postulated intermediates in the biosynthesis of mollisin. Practical aspects of stilbene photocyclisations are outlined in the final section of the Introduction. The biosynthesis of mollisin is discussed in Chapter 1 and is proposed to involve chlorination and then ring degradation of a polyketide derived phenanthrene (14), (15) or (16). Chapter 1 also records the disappointing result of feeding sodium [2-H3, 1-13 C]- acetate to malt agar cultures of M. caesia during the present investigation. Thus it was proposed to study the biosynthesis of mollisin by feeding deuterium labelled phenanthrenes (14) - (16) to the fungal medium. Chapters 2, 3 and 4 describe attempts to synthesise the postulated biosynthetic intermediates. The synthesis, properties and photochemistry of ortho-halostilbenes with alpha'-acetoxy-alpha-cyano or alpha'-acetoxy-alpha-carbomethoxy substituents are recorded in Chapters 2 and 3 respectively. The evidence from the photochemical experiments indicates that an ortho-halo substituent cannot be used to regio-chemically control the cyclisation step in these systems. As outlined in Chapter 3, a significant result was the finding that the 9-carbo-methoxyl group of phenanthrene (173) can be easily removed with simultaneous hydrolysis of the 10-acetoxyl group upon treatment with aqueous base. Chapter 4 mainly deals with attempts to synthesise phenanthrene (14) using benzyl protecting groups for the phenolic substituents in the starting materials. Unfortunately, no feeding experiments employing deuterium labelled phenanthrenes were conducted. However, many interesting results were obtained in connection with the photochemical synthesis of phenanthrenes

Comparison among strains of tobacco cultivar Hicks illustrating variability within a single cultivar

Random effect models were used to compare seven strains of Hicks tobacco at two sites for 3 years in north Queensland. Broadleaf Hicks (U.S.A.) was found to be commercially and significantly superior to the local strain. There were no differences in quality, but the saleable yield of the introduction was 129% of that of the Queensland strain, and the former was not inferior in any other important characteristic. The new strain has been renamed "Hicks Q46" for local use. Commercial and statistical significances of the results were contrasted. The most divergent strains were identified, Coley Special being the strain most different from the average Hicks phenotype in the test environments

The relationship between obesity and self-esteem: longitudinal evidence from Australian adults

We examine whether low self-esteem increases the risk of obesity in a panel of Australian adults. To address the problem of endogeneity, we look at weight changes following exogenous shocks to self-esteem, such as the unexpected death of friends and family members. We find that negative shocks adversely affect self-esteem in turn leading to large increases in weight via increased food consumption and reduced exercise. The effects of the negative shocks were found to be larger for the lower educated and females

Dermoscopic evaluation of amelanotic and hypomelanotic melanoma

Objective: To determine the predictive dermoscopic features of amelanotic and hypomelanotic melanoma