Prevalence and clinical aspects when it comes to the association between type 1 diabetes mellitus (DM1) and celiac disease

OBJECTIVES: To estimate the prevalence of type 1 diabetes mellitus (DM1) and celiac disease association and to verify the existence of celiac disease symptoms, as well as the occurrence of other autoimmune diseases among the patients, their first-degree relatives and the possible influences of celiac disease in diabetes control. METHODS: It was done a cross-sectional study with 195 patients that answered a questionnaire about gastrointestinal symptoms and the occurrence of autoimmune diseases in their first-degree relatives. IgA was measured and antiendomysial antibody (EMA) was screened. The patients with positive EMA were submitted to intestinal biopsy. Those with celiac disease confirmed by biopsy (case group) were paired with DM1 patients without celiac disease (control group) according to age on diabetes diagnosis, diabetes duration and gender. RESULTS: EMA was positive in nine patients. In seven of them the biopsy has confirmed celiac disease (4.0%). Comparing the cases with controls, the gastrointestinal symptoms were significantly more frequent in the first group, but there was no difference between the groups regarding to the occurrence of autoimmune disease among the first-degree relatives and regarding to the control of diabetes (z weight, z height, insulin dose, HbA1c). CONCLUSIONS: The prevalence found was 4.0%. This sample of celiac patients showed a predominance of gastrointestinal symptoms, although the celiac disease did not influence the diabetes control.OBJETIVOS: Verificar a prevalência da associação entre diabetes melito tipo 1 (DM1) e doença celíaca (DC) e a presença de sintomas da DC, a ocorrência de outras doenças auto-imunes entre os pacientes e seus parentes de primeiro grau e as possíveis influências da DC no controle do diabetes. MÉTODOS: Estudo transversal com 195 pacientes com DM1, que responderam ao questionário sobre a presença de sintomas gastrintestinais e a ocorrência de doenças auto-imunes em familiares. Foi dosada a IgA sérica e pesquisado o anticorpo antiendomísio (EMA). Os pacientes com EMA positivo foram submetidos à biópsia intestinal. Aqueles com DC confirmada por biópsia (grupo-casos) foram pareados com os pacientes apenas diabéticos (grupo-controle), de acordo com a idade ao diagnóstico de diabetes, o tempo de duração da doença e o gênero. RESULTADOS: O EMA foi positivo em nove pacientes. Em sete a biópsia confirmou DC (prevalência de 4%). No pareamento de casos (DM1 e DC) e controles (somente DM1), os sintomas gastrintestinais foram significativamente mais freqüentes no grupo casos, não sendo observada diferença com a ocorrência de doenças auto-imunes entre os parentes de primeiro grau e com o controle do diabetes (z peso, z estatura, dose de insulina e HbA1c). CONCLUSÕES: A prevalência de DC neste grupo de pacientes com DM1 foi de 4%. A amostra de pacientes celíacos apresentou predomínio de sintomas gastrintestinais, porém a presença de DC não interferiu no controle do diabetes.63564

About one o'clock Friday morning, September 12th, Joe. Parker and Ed. Williams broke jail here and escaped.

About one o'clock Friday morning, September 12th, Joe. Parker and Ed. Williams broke jail here and escaped. Parker is charged with MURDER and Williams is charged with picking pockets. They are supposed to be together. Parker is a mulatto, 32 years old, five feet ten, and weighs about 180 pounds; Is smooth face and rather good looking; Has a flat nose, well-kept wavy hair; walks with a swagger and wears a dark suit. He has prominent scars on throat, caused by trying t commit suicide. He has been a pugilist. Is a molder by occupation and also understands the process of mixing Malleable Iron. One hundred dollars reward for his arrest and detention until identified. Ed• Williams, charged with picking pockets, is 23 years old, five feet eight inches tall, weighs 150 pounds; medium build, blue eyes, dark brown hair, long smooth face, parts hair in middle; small scar back of right hand; scar second joint first finger left hand, One bad tooth front upper jaw; wore soft hat creased in top; wore dark clothes. Twenty-five dollars reward for his arrest and detention until identified. Wire all information, at our expense, to JOHN C. WHITACKER, Supt. Police, Dayton Ohio Or WM. C. KERSHNER, Sheriff Montgomery Co

About one o'clock Friday morning, September 12th, Joe. Parker and Ed. Williams broke jail here and escaped.

About one o'clock Friday morning, September 12th, Joe. Parker and Ed. Williams broke jail here and escaped. Parker is charged with MURDER and Williams is charged with picking pockets. They are supposed to be together. Parker is a mulatto, 32 years old, five feet ten, and weighs about 180 pounds; Is smooth face and rather good looking; Has a flat nose, well-kept wavy hair; walks with a swagger and wears a dark suit. He has prominent scars on throat, caused by trying t commit suicide. He has been a pugilist. Is a molder by occupation and also understands the process of mixing Malleable Iron. One hundred dollars reward for his arrest and detention until identified. Ed• Williams, charged with picking pockets, is 23 years old, five feet eight inches tall, weighs 150 pounds; medium build, blue eyes, dark brown hair, long smooth face, parts hair in middle; small scar back of right hand; scar second joint first finger left hand, One bad tooth front upper jaw; wore soft hat creased in top; wore dark clothes. Twenty-five dollars reward for his arrest and detention until identified. Wire all information, at our expense, to JOHN C. WHITACKER, Supt. Police, Dayton Ohio Or WM. C. KERSHNER, Sheriff Montgomery Co

[prevalence And Clinical Aspects When It Comes To The Association Between Type 1 Diabetes Mellitus (dm1) And Celiac Disease].

To estimate the prevalence of type 1 diabetes mellitus (DM1) and celiac disease association and to verify the existence of celiac disease symptoms, as well as the occurrence of other autoimmune diseases among the patients, their first-degree relatives and the possible influences of celiac disease in diabetes control. It was done a cross-sectional study with 195 patients that answered a questionnaire about gastrointestinal symptoms and the occurrence of autoimmune diseases in their first-degree relatives. IgA was measured and antiendomysial antibody (EMA) was screened. The patients with positive EMA were submitted to intestinal biopsy. Those with celiac disease confirmed by biopsy (case group) were paired with DM1 patients without celiac disease (control group) according to age on diabetes diagnosis, diabetes duration and gender. EMA was positive in nine patients. In seven of them the biopsy has confirmed celiac disease (4.0%). Comparing the cases with controls, the gastrointestinal symptoms were significantly more frequent in the first group, but there was no difference between the groups regarding to the occurrence of autoimmune disease among the first-degree relatives and regarding to the control of diabetes (z weight, z height, insulin dose, HbA1c). The prevalence found was 4.0%. This sample of celiac patients showed a predominance of gastrointestinal symptoms, although the celiac disease did not influence the diabetes control.52635-4

Agroecological practices as territorial development: an analytical schema from Brazilian case studies

Agroecological practices have been widely promoted as an alternative to the hegemonic agri-food system, yet they also can help to ‘green’ the system. To strengthen a transformative agroecology, Latin American activists have promoted the concept desenvolvimento territorial rural (DTR or rural territorial development), which has different versions. The dominant version advocates broad multi-actor coalitions to strengthen DTR and thus benefit poor people, yet this obscures rival territorial agendas. An antagonistic version instead analyses how capital accumulation drives societal conflicts, contingently resulting in DTR trajectories. Here an analytical schema helps identify how agroecological practices are appropriated for diverse trajectories of territorial development, illustrated by Brazilian agroforestry case studies