38 research outputs found

    Cannabinoidrezeptor CB1 und Endothelin-B-Rezeptor : Interaktion im Hippokampus

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    A gauge theoretic approach to elasticity with microrotations

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    We formulate elasticity theory with microrotations using the framework of gauge theories, which has been developed and successfully applied in various areas of gravitation and cosmology. Following this approach, we demonstrate the existence of particle-like solutions. Mathematically this is due to the fact that our equations of motion are of Sine-Gordon type and thus have soliton type solutions. Similar to Skyrmions and Kinks in classical field theory, we can show explicitly that these solutions have a topological origin.Comment: 15 pages, 1 figure; revised and extended version, one extra page; revised and extended versio

    Observational Constraints on Teleparallel Dark Energy

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    We use data from Type Ia Supernovae (SNIa), Baryon Acoustic Oscillations (BAO), and Cosmic Microwave Background (CMB) observations to constrain the recently proposed teleparallel dark energy scenario based on the teleparallel equivalent of General Relativity, in which one adds a canonical scalar field, allowing also for a nonminimal coupling with gravity. Using the power-law, the exponential and the inverse hyperbolic cosine potential ansatzes, we show that the scenario is compatible with observations. In particular, the data favor a nonminimal coupling, and although the scalar field is canonical the model can describe both the quintessence and phantom regimes.Comment: 19 pages, 6 figures, version accepted by JCA

    Phase-Space analysis of Teleparallel Dark Energy

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    We perform a detailed dynamical analysis of the teleparallel dark energy scenario, which is based on the teleparallel equivalent of General Relativity, in which one adds a canonical scalar field, allowing also for a nonminimal coupling with gravity. We find that the universe can result in the quintessence-like, dark-energy-dominated solution, or to the stiff dark-energy late-time attractor, similarly to standard quintessence. However, teleparallel dark energy possesses an additional late-time solution, in which dark energy behaves like a cosmological constant, independently of the specific values of the model parameters. Finally, during the evolution the dark energy equation-of-state parameter can be either above or below -1, offering a good description for its observed dynamical behavior and its stabilization close to the cosmological-constant value.Comment: 23 pages, 4 figures, 5 tables, version published at JCA

    Maximal symmetry and metric-affine f(R) gravity

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    The affine connection in a space-time with a maximally symmetric spatial subspace is derived using the properties of maximally symmetric tensors. The number of degrees of freedom in metric-affine gravity is thereby considerably reduced while the theory allows spatio-temporal torsion and remains non-metric. The Ricci tensor and scalar are calculated in terms of the connection and the field equations derived for the Einstein-Hilbert as wells as for f(R) Lagrangians. By considering specific forms of f(R), we demonstrate that the resulting Friedmann equations in Palatini formalism without torsion and metric-affine formalism with maximal symmetry are in general different in the presence of matter.Comment: 7 page

    Existence of relativistic stars in f(T) gravity

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    We examine the existence of relativistic stars in f(T) modified gravity and explicitly construct several classes of static perfect fluid solutions. We derive the conservation equation from the complete f(T) gravity field equations and present the differences with its teleparallel counterpart. Firstly, we choose the tetrad field in the diagonal gauge and study the resulting field equations. Some exact solutions are explicitly constructed and it is noted that these solutions have to give a constant torsion scalar. Next, we choose a non diagonal tetrad field which results in field equations similar to those of general relativity. For specific models we are able to construct exact solutions of these field equations. Among those new classes of solutions, we find negative pressure solutions, and an interesting class of polynomial solutions.Comment: 19 pages; substantially revised and extended version, off diagonal tetrad discussion adde

    Varying constants, Gravitation and Cosmology

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    Fundamental constants are a cornerstone of our physical laws. Any constant varying in space and/or time would reflect the existence of an almost massless field that couples to matter. This will induce a violation of the universality of free fall. It is thus of utmost importance for our understanding of gravity and of the domain of validity of general relativity to test for their constancy. We thus detail the relations between the constants, the tests of the local position invariance and of the universality of free fall. We then review the main experimental and observational constraints that have been obtained from atomic clocks, the Oklo phenomenon, Solar system observations, meteorites dating, quasar absorption spectra, stellar physics, pulsar timing, the cosmic microwave background and big bang nucleosynthesis. At each step we describe the basics of each system, its dependence with respect to the constants, the known systematic effects and the most recent constraints that have been obtained. We then describe the main theoretical frameworks in which the low-energy constants may actually be varying and we focus on the unification mechanisms and the relations between the variation of different constants. To finish, we discuss the more speculative possibility of understanding their numerical values and the apparent fine-tuning that they confront us with.Comment: 145 pages, 10 figures, Review for Living Reviews in Relativit

    Hippocampal cannabinoid-1 receptor upregulation upon endothelin-B receptor deficiency: A neuroprotective substitution effect ?

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    Endothelin (ETB)-receptors mediate anti-apoptotic actions. Lack of functional ETB-receptors leads to increased neuronal apoptosis in the hippocampus. The increased apoptosis must be compensated by other mechanisms, however, as ETB-deficient rats display normal overall brain morphology. To illuminate on brain plasticity in ETB-receptor deficiency, we studied the expression and function of another neuroprotective system, the cannabinoid CB1-receptors, in ETB-deficient hippocampus. We show that CB1 expression in hippocampus increases postnatally in all rats but that the increase in CB1-receptor expression is significantly higher in ETB-deficient compared to wildtype littermates. Neuronal apoptosis decreases during brain maturation but remains on a significantly higher level in the ETB-deficient compared to wildtype dentate. When investigating survival of hippocampal neurons in culture, we found significant protection against hypoxia-induced cell death with CB1-analogs (noladin, (9-tetrahydrocannabinol) only in ETB-deficient neurons. We suggest that CB1-receptor upregulation in the ETB-mutant hippocampus reflects an attempt to compensate for the lack of ETB-receptors
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