1,008 research outputs found

    Spectra of Free Diquark in the Bethe-Salpeter Approach

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    In this work, we employ the Bethe-Salpeter (B-S) equation to investigate the spectra of free diquarks and their B-S wave functions. We find that the B-S approach can be consistently applied to study the diqaurks with two heavy quarks or one heavy and one light quarks, but for two light-quark systems, the results are not reliable. There are a few free parameters in the whole scenario which can only be fixed phenomenologically. Thus, to determine them, one has to study baryons which are composed of quarks and diquarks.Comment: 16 pages, no figure

    Classification of protein interaction sentences via gaussian processes

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    The increase in the availability of protein interaction studies in textual format coupled with the demand for easier access to the key results has lead to a need for text mining solutions. In the text processing pipeline, classification is a key step for extraction of small sections of relevant text. Consequently, for the task of locating protein-protein interaction sentences, we examine the use of a classifier which has rarely been applied to text, the Gaussian processes (GPs). GPs are a non-parametric probabilistic analogue to the more popular support vector machines (SVMs). We find that GPs outperform the SVM and na\"ive Bayes classifiers on binary sentence data, whilst showing equivalent performance on abstract and multiclass sentence corpora. In addition, the lack of the margin parameter, which requires costly tuning, along with the principled multiclass extensions enabled by the probabilistic framework make GPs an appealing alternative worth of further adoption

    An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

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    For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types

    Heavy quarkonium: progress, puzzles, and opportunities

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    A golden age for heavy quarkonium physics dawned a decade ago, initiated by the confluence of exciting advances in quantum chromodynamics (QCD) and an explosion of related experimental activity. The early years of this period were chronicled in the Quarkonium Working Group (QWG) CERN Yellow Report (YR) in 2004, which presented a comprehensive review of the status of the field at that time and provided specific recommendations for further progress. However, the broad spectrum of subsequent breakthroughs, surprises, and continuing puzzles could only be partially anticipated. Since the release of the YR, the BESII program concluded only to give birth to BESIII; the BB-factories and CLEO-c flourished; quarkonium production and polarization measurements at HERA and the Tevatron matured; and heavy-ion collisions at RHIC have opened a window on the deconfinement regime. All these experiments leave legacies of quality, precision, and unsolved mysteries for quarkonium physics, and therefore beg for continuing investigations. The plethora of newly-found quarkonium-like states unleashed a flood of theoretical investigations into new forms of matter such as quark-gluon hybrids, mesonic molecules, and tetraquarks. Measurements of the spectroscopy, decays, production, and in-medium behavior of c\bar{c}, b\bar{b}, and b\bar{c} bound states have been shown to validate some theoretical approaches to QCD and highlight lack of quantitative success for others. The intriguing details of quarkonium suppression in heavy-ion collisions that have emerged from RHIC have elevated the importance of separating hot- and cold-nuclear-matter effects in quark-gluon plasma studies. This review systematically addresses all these matters and concludes by prioritizing directions for ongoing and future efforts.Comment: 182 pages, 112 figures. Editors: N. Brambilla, S. Eidelman, B. K. Heltsley, R. Vogt. Section Coordinators: G. T. Bodwin, E. Eichten, A. D. Frawley, A. B. Meyer, R. E. Mitchell, V. Papadimitriou, P. Petreczky, A. A. Petrov, P. Robbe, A. Vair

    Partial Wave Analysis of J/ψγ(K+Kπ+π)J/\psi \to \gamma (K^+K^-\pi^+\pi^-)

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    BES data on J/ψγ(K+Kπ+π)J/\psi \to \gamma (K^+K^-\pi^+\pi^-) are presented. The KKˉK^*\bar K^* contribution peaks strongly near threshold. It is fitted with a broad 0+0^{-+} resonance with mass M=1800±100M = 1800 \pm 100 MeV, width Γ=500±200\Gamma = 500 \pm 200 MeV. A broad 2++2^{++} resonance peaking at 2020 MeV is also required with width 500\sim 500 MeV. There is further evidence for a 2+2^{-+} component peaking at 2.55 GeV. The non-KKˉK^*\bar K^* contribution is close to phase space; it peaks at 2.6 GeV and is very different from KKˉK^{*}\bar{K^{*}}.Comment: 15 pages, 6 figures, 1 table, Submitted to PL

    The Origin, Early Evolution and Predictability of Solar Eruptions

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    Coronal mass ejections (CMEs) were discovered in the early 1970s when space-borne coronagraphs revealed that eruptions of plasma are ejected from the Sun. Today, it is known that the Sun produces eruptive flares, filament eruptions, coronal mass ejections and failed eruptions; all thought to be due to a release of energy stored in the coronal magnetic field during its drastic reconfiguration. This review discusses the observations and physical mechanisms behind this eruptive activity, with a view to making an assessment of the current capability of forecasting these events for space weather risk and impact mitigation. Whilst a wealth of observations exist, and detailed models have been developed, there still exists a need to draw these approaches together. In particular more realistic models are encouraged in order to asses the full range of complexity of the solar atmosphere and the criteria for which an eruption is formed. From the observational side, a more detailed understanding of the role of photospheric flows and reconnection is needed in order to identify the evolutionary path that ultimately means a magnetic structure will erupt

    Beaches of islands of tractability : algorithms for parsimony and minimum perfect phylogeny haplotyping problems

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    The problem Parsimony Haplotyping ðPHÞ asks for the smallest set of haplotypes that can explain a given set of genotypes, and the problem Minimum Perfect Phylogeny Haplotyping ðMPPHÞ asks for the smallest such set that also allows the haplotypes to be embedded in a perfect phylogeny, an evolutionary tree with biologically motivated restrictions. For PH, we extend recent work by further mapping the interface between “easy” and “hard” instances, within the framework of ðk; ‘Þ-bounded instances, where the number of 2s per column and row of the input matrix is restricted. By exploring, in the same way, the tractability frontier of MPPH, we provide the first concrete positive results for this problem. In addition, we construct for both PH and MPPH polynomial time approximation algorithms, based on properties of the columns of the input matrix

    Analysis of the X(1835) and related baryonium states with Bethe-Salpeter equation

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    In this article, we study the mass spectrum of the baryon-antibaryon bound states ppˉp\bar{p}, ΣΣˉ\Sigma\bar{\Sigma}, ΞΞˉ\Xi\bar{\Xi}, ΛΛˉ\Lambda\bar{\Lambda}, pNˉ(1440)p\bar{N}(1440), ΣΣˉ(1660)\Sigma\bar{\Sigma}(1660), ΞΞˉ\Xi\bar{\Xi}^\prime and ΛΛˉ(1600)\Lambda\bar{\Lambda}(1600) with the Bethe-Salpeter equation. The numerical results indicate that the ppˉp\bar{p}, ΣΣˉ\Sigma\bar{\Sigma}, ΞΞˉ\Xi\bar{\Xi}, pNˉ(1440)p\bar{N}(1440), ΣΣˉ(1660)\Sigma\bar{\Sigma}(1660), ΞΞˉ\Xi\bar{\Xi}^\prime bound states maybe exist, and the new resonances X(1835) and X(2370) can be tentatively identified as the ppˉp\bar{p} and pNˉ(1440)p\bar{N}(1440) (or N(1400)pˉN(1400)\bar{p}) bound states respectively with some gluon constituents, and the new resonance X(2120) may be a pseudoscalar glueball. On the other hand, the Regge trajectory favors identifying the X(1835), X(2120) and X(2370) as the excited η(958)\eta^\prime(958) mesons with the radial quantum numbers n=3n=3, 4 and 5, respectively.Comment: 13 pages, 2 figures, revise a numbe
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