855 research outputs found

    Discursos de San Bernardo, abad de Claraval, sobre el Cántico de los Cánticos de Salomon

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    Copia digital. Valladolid : Junta de Castilla y León. Consejería de Cultura y Turismo, 2009-2010Sign.: []2, 2*4, 3*4, A-Z4, 2a-2z4, 3a-3d4Antep

    Coherent Moving States in Highway Traffic (Originally: Moving Like a Solid Block)

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    Recent advances in multiagent simulations have made possible the study of realistic traffic patterns and allow to test theories based on driver behaviour. Such simulations also display various empirical features of traffic flows, and are used to design traffic controls that maximise the throughput of vehicles in heavily transited highways. In addition to its intrinsic economic value, vehicular traffic is of interest because it may throw light on some social phenomena where diverse individuals competitively try to maximise their own utilities under certain constraints. In this paper, we present simulation results that point to the existence of cooperative, coherent states arising from competitive interactions that lead to a new phenomenon in heterogeneous highway traffic. As the density of vehicles increases, their interactions cause a transition into a highly correlated state in which all vehicles practically move with the same speed, analogous to the motion of a solid block. This state is associated with a reduced lane changing rate and a safe, high and stable flow. It disappears as the vehicle density exceeds a critical value. The effect is observed in recent evaluations of Dutch traffic data.Comment: Submitted on April 21, 1998. For related work see http://www.theo2.physik.uni-stuttgart.de/helbing.html and http://www.parc.xerox.com/dynamics

    Ectopic hbox12 Expression Evoked by Histone Deacetylase Inhibition Disrupts Axial Specification of the Sea Urchin Embryo

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    Dorsal/ventral patterning of the sea urchin embryo depends upon the establishment of a Nodal-expressing ventral organizer. Recently, we showed that spatial positioning of this organizer relies on the dorsal-specific transcription of the Hbox12 repressor. Building on these findings, we determined the influence of the epigenetic milieu on the expression of hbox12 and nodal genes. We find that Trichostatin-A, a potent and selective histone-deacetylases inhibitor, induces histone hyperacetylation in hbox12 chromatin, evoking broad ectopic expression of the gene. Transcription of nodal concomitantly drops, prejudicing dorsal/ventral polarity of the resulting larvae. Remarkably, impairing hbox12 function, either in a spatially-restricted sector or in the whole embryo, specifically rescues nodal transcription in Trichostatin-A-treated larvae. Beyond strengthen the notion that nodal expression is not allowed in the presence of functional Hbox12 in the same cells, these results highlight a critical role of histone deacetylases in regulating the spatial expression of hbox12

    [Graduale]

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    Copia digital. Madrid : Ministerio de Cultura. Subdirección General de Coordinación Bibliotecaria, 200

    Super Evangelium "Missus est" [Manuscrito]

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    Copia digital. Madrid : Ministerio de Cultura. Subdirección General de Coordinación Bibliotecaria, 2006Procede de la desamortización del Monasterio cisterciense de Santes Creus (Tarragona)Forma parte de un volumen facticio; por la foliación medieval se aprecia que formó parte de un volumen facticio más antiguo junto con los bloques inmediatamente anterior (al que seguiría, como en la actualidad) y posterior (que precedía a ambos)Cuadernos de 12 h. (salvo por las h. sobrantes recortadas al final); pautado a lápiz; caja de escr.: 13 x 10 cm; foliación medieval y moderna como parte de un vol. factici

    [De laudibus Virginis Matris] [Manuscrito]

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    Ms. facticioProcede de la desamortización del Monasterio de San Millán, estuvo depositado en la Biblioteca de Cortes, desde donde pasó a la Biblioteca de la Real Academia de la HistoriaCuadernos de 8 h. ; reclamos ; foliación moderna a lápiz en arábigos ; pautado a mina de plomo ; caja de esc.: 25 x 19 cm ; títulos corrientes y letras de aviso ; existen lagunas en el texto, que está incompletoIniciales ornamentadas con lacerías ; esquemas métricos inscritos en unas arquería de herradura (h. 13v-15r.

    Opera diletteuole et nuoua de gratitudine et liberalita. Doue si contiene, un notabile caso, de magnanimita usate infra due gentilhuomini. Essempio raro & degno di essere da qualunque animo generoso inteso. In elegante parlare, dal eximio philosopho

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    [28] c. ; 8 Riferimenti: Edit 16. CNCE 25658; M. Bersano Begey, Le cinquecentine piemontesi, v. 2, n. 1015 Marca (U986) del Garrone in fine Front. in cornice xilografic

    Obra pia, y eficaz modo para remediar la miseria de la gente pobre de España...

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    Sign. : [calderón]6, A-M2Grab. xil. en inicial de la p.

    [Sermones in Cantica Canticorum] [Manuscrito] [; De consideratione ad Eugenium ; De praecepto et de dispensatione

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    Copia digital. Madrid : Ministerio de Cultura. Subdirección General de Coordinación Bibliotecaria, 2006Procede de la desamortización del Monasterio de Santes Creus (Tarragona)Tit. tomado de Domínguez BordonaIniciales en roj
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