OMNIgene.SPUTUM suppresses contaminants whilst maintaining Mycobacterium tuberculosis viability and obviates cold-chain transport

The study was funded by DNA Genotek Inc. Canada, the manufacturer of OMNIgene.SPUTUM (grant number SMD0-Z0B014).Tuberculosis (TB) diagnostics are centralised, requiring long-distance transportation of specimens in most resource-limited settings. We evaluated the ability of OMNIgene.SPUTUM (OM-S) to obviate cold-chain transport of TB specimens. A two-arm (same-day and after 5 days sample processing) study was conducted to assess contamination rates and Mycobacterium tuberculosis viability in OM-S-treated samples against the standard decontamination procedure (SDP) in Mozambique, using Lowenstein Jensen (LJ) and mycobacterial growth indicator tube (MGIT) culture and molecular bacterial load assay. 270 specimens were processed using OM-S and SDP in same-day and 5-day arms. Contamination was lower in OM-S-treated than SDP-treated cultures: 12% versus 15% and 2% versus 27% in the same-day and 5-day arms, respectively. M. tuberculosis recovery in OM-S-treated LJ cultures was 10% and 56% higher in the same-day and 5-day arms, respectively, than SDP-treated cultures, but lower in MGIT (52% and 28% lower in the same-day and 5-day arms, respectively). M. tuberculosis viable count was 1log estimated CFU·mL−1 lower in 5-day OM-S-treated sputa. OM-S was more effective at liquefying sputum with a shorter sample processing time: 22 min for culture. OM-S is simple to use and has demonstrated a high potency to suppress contaminants, maintenance of viability at ambient temperatures and higher M. tuberculosis recovery, particularly in the solid LJ cultures. Optimisation of OM-S to achieve higher MGIT culture positivity and shorter time to result will increase its application and utility in the clinical management of TB.Publisher PDFPeer reviewe

Rentabilidade do setor bancário e crescimento económico em Moçambique entre 1996 e 2017

O presente estudo analisa a relação entre a rentabilidade do setor bancário e o crescimento económico em Moçambique no período entre 1996 e 2017. Este trabalho tem como objetivo analisar a relação entre a rentabilidade bancária e o crescimento económico em Moçambique. Este estudo permite avaliar a real importância dos resultados obtidos no setor bancário para a estabilidade financeira e crescimento económico. Para verificar a relação entre as variáveis, utilizou-se dados anuais do ROA ("Return On Assets") para representar a rentabilidade do setor bancário e o PIB per Capita para o crescimento económico. Para o efeito a analise baseou-se na estimação do modelo econométrico ARDL ("Autoregressive Distributed Lag") de cointegração através da reparametrização para o modelo de correção de erros (ECM). Com base nos resultados obtidos concluiu-se que a longo prazo o ROA tem efeito negativo no PIB "per capita" em Moçambique.The present study analyzes the relationship between the profitability of the banking sector and economic growth in Mozambique in the period between 1996 and 2017. This work aims to analyze the relationship between bank profitability and economic growth in Mozambique. This study makes it possible to assess the real importance of the results obtained in the banking sector for financial stability and economic growth. To verify the relationship between the variables, annual ROA (Return On Assets) data was used to represent the profitability of the banking sector and GDP per capita for economic growth. For this purpose, the analysis was based on the estimation of the econometric model ARDL (Autoregressive Distributed Lag) of cointegration through reparametrization for the error correction model (ECM). Based on the results obtained, it was concluded that in the long run ROA has a negative effect on GDP per capita in Mozambiqu

Rentabilidade do setor bancário e crescimento económico em Moçambique entre 1996 e 2017

O presente estudo analisa a relação entre a rentabilidade do setor bancário e o crescimento económico em Moçambique no período entre 1996 e 2017. Este trabalho tem como objetivo analisar a relação entre a rentabilidade bancária e o crescimento económico em Moçambique. Este estudo permite avaliar a real importância dos resultados obtidos no setor bancário para a estabilidade financeira e crescimento económico. Para verificar a relação entre as variáveis, utilizou-se dados anuais do ROA ("Return On Assets") para representar a rentabilidade do setor bancário e o PIB per Capita para o crescimento económico. Para o efeito a analise baseou-se na estimação do modelo econométrico ARDL ("Autoregressive Distributed Lag") de cointegração através da reparametrização para o modelo de correção de erros (ECM). Com base nos resultados obtidos concluiu-se que a longo prazo o ROA tem efeito negativo no PIB "per capita" em Moçambique.The present study analyzes the relationship between the profitability of the banking sector and economic growth in Mozambique in the period between 1996 and 2017. This work aims to analyze the relationship between bank profitability and economic growth in Mozambique. This study makes it possible to assess the real importance of the results obtained in the banking sector for financial stability and economic growth. To verify the relationship between the variables, annual ROA (Return On Assets) data was used to represent the profitability of the banking sector and GDP per capita for economic growth. For this purpose, the analysis was based on the estimation of the econometric model ARDL (Autoregressive Distributed Lag) of cointegration through reparametrization for the error correction model (ECM). Based on the results obtained, it was concluded that in the long run ROA has a negative effect on GDP per capita in Mozambiqu

Instrumental Orchestration: Managing and Varying Work Modalities with Digital Tools (interview)

Dans le cadre d'un travail de Master, a été mené une recherche sur l'orchestration instrumentale des tablettes numériques en classe. Plus particulièrement, on s'est intéressé à la prise en compte de cette question au moment de la planification de l'enseignement par des enseignants du secondaire 1. Cette approche est particulièrement intéressante, car elle permet de penser comment travailler à plusieurs - élèves et enseignant - avec les outils numériques tels les iPads en classe.As part of a Master's thesis, research was conducted on the instrumental orchestration of digital tablets in the classroom. More specifically, the study focused on how this issue is considered by lower secondary school teachers during their lesson planning. This approach is particularly interesting because it allows us to consider how multiple individuals—students and teachers—can work together effectively with digital tools like iPads in the classroom

A relação entre a qualidade do serviço e o comportamento de compra: o caso da cantina da Faculdade de Economia

The products and sales strategies used by today's companies are a direct translation of the changes that have taken place in the tastes, preferences and buying behavior of consumers, and these are the key element that dictate the new rules of the companies, surviving only those that achieve accompany these behavioral changes with the same level of quality and expected performance. In this sense, the present work aims to study the extent to which the quality of service provided by the canteen of the Faculty of Economics influences the buying behavior of students on Campusof EMU.The research strategy was based on a case study about the canteen of the Faculty of Economics and the data for the materialization of the work were collected in books, scientific articles, interview to the managers of the canteen and a questionnaire elaborated and directed to a target group of randomly chosen students, seeking their behaviors, experiences and expectations linked to the products and services offered by the canteen. As a general conclusion, it was found that there is no direct relationship between the service provided by the Faculty of Economics canteen and students' purchasing behavior, since they attend the canteen not because of the superior quality of the service offered as a whole, but because satisfaction of their basic needs through factors such as the diversity, quality and reliability of products sold, as well as easy access to it and the possibility of meeting and gathering of friends in a single space. Thus denying the hypothesis placed in the introduction of the research, where the perceived superior quality of the service provided by the School of Economics was the reason forthe favorable purchasing behavior of the students of the EMU Campus.2021-08-21Os produtos e as estratégias de venda usadas pelas empresas actuais são uma tradução directa das mudanças que aconteceram nos gostos, nas preferências e no comportamento de compra dos consumidores, sendo estes o elemento chave que dita as novas regras das empresas, sobrevivendo somente as que conseguem acompanhar estas alterações de comportamento com o mesmo nível de qualidade e desempenho esperado. Neste sentido, a presente dissertação visa estudar até que ponto a qualidade do serviço prestado pela cantina da Faculdade de Economia influencia no comportamento de compra dos estudantes do Campus da UEM. A estratégia de pesquisa baseou-se num estudo de caso sobre a cantina da Faculdade de Economia e os dados para a materialização do trabalho foram colectados em livros, artigos científicos, entrevista aos gerentes da cantina e um questionário elaborado e direccionado a um grupo-alvo de estudantes aleatoriamente escolhidos, buscando seus comportamentos, experiências e expectativas ligadas aos produtos e serviços oferecidos pela cantina. Como conclusão geral, verificou-se que não existe uma relação directa entre o serviço prestado pela cantina da Faculdade de Economia e o comportamento de compra dos estudantes, pois estes frequentam a cantina não pela qualidade superior do serviço oferecido como um todo, mas sim pela satisfação das suas necessidades básicas por via de factores como a diversidade, qualidade e confiabilidade dos produtos vendidos, assim como o fácil acesso a mesma e a possibilidade de concentração e encontro dos amigos num único espaço. Negando desta forma a hipótese colocada na introdução da pesquisa, onde a qualidade superior percebida do serviço prestado pela cantina da Faculdade de Economia era a razão para o comportamento de compra favorável dos estudantes do Campus da UEM

State-of-the-art on Virtualization and Software Defined Networking for Efficient Resource Allocation on Multi-tenant 5G Networks

Global data traffic explosion is expected to set stringent requirements for next generation networks in the next decades. Besides, very low latencies will have to be guaranteed for enabling new delay critical services. However, current Software Defined Networking (SDN) solutions have limitations in terms of separating both data and control planes among tenants/operators, and the capability to adapt to new or changing requirements. Moreover, some virtualization schemes do not ensure isolation of resources and do not guarantee bandwidth across the entities. While some others fail to provide flexibility to the slices to customize the resource allocation across the users. Therefore, novel SDN and virtualization techniques should be implemented to realize the upcoming 5G network that will facilitate at least efficient resource allocation and multi-tenancy among the plethora of different requirements

A experiência espácio-temporal na arquitectura : entre o real e o imaginário

Dissertação de mestrado integrado em Arquitectura, Universidade Lusíada de Lisboa, 2014Exame público realizado em 25 de Fevereiro de 2015A presente dissertação constitui matéria de reflexão sobre a significação do espaço arquitectónico na perspectiva de um observador em movimento. Pela capacidade intrínseca de simular esta experiência, a imagem-movimento permite uma maior consciencialização da mesma, influenciando o pensamento e imaginário espacial dos arquitectos. Neste sentido, abordamos a sua constituição, recorrendo depois à dialéctica entre arquitectura e cinema, como método de desenvolvimento do tema proposto