150 research outputs found
Blurring the Boundaries: Integrating Techniques of Land Surveying on the Qing’s Mongolian Frontier
This article focuses on the role of spatial dynamics in effectuating the integration of two different sets of land surveying techniques. During the later stages of the Qing-Zunghar wars of the 1690s, the Kangxi emperor (r. 1661-1722) repeatedly asked French Jesuit missionaries, who had been sent to China in 1685 under the patronage of the French King Louis XIV, to join his imperial campaigns targeting the Khalkha-Mongolian borderlands. In the shadow of these imperial journeys, missionaries systematically determined latitudes with Paris-made instruments while Qing officials measured road distances all along the way with graduated ropes. A next step in the evolution of imperial cartographic practice came after the Qing-Zunghar wars had come to an end, when an all-out effort was launched by the emperor to integrate the newly conquered Khalkha Mongols and their lands into the Qing polity. As part of the effort, missionaries were asked to produce a map of the new frontier by integrating European and East Asian practices, which led to the discovery of a technical incompatibility. In 1702, the problem was solved by the precise measurement of the terrestrial degree and, immediately after, the restandardization of the Qing’s most basic unit of length, the chi 尺. Thus, the turn of the eighteenth century saw the crystallization of a new or hybrid Qing cartographic practice, driven by the need to explore the new Khalkha frontier. Selected techniques developed by the French Academy of Sciences were gradually absorbed into a pre-existing framework of Qing land surveying, a process that was shaped and facilitated by exchanges in via throughout the vast Mongolian frontier
A case study of records management practices in historic motor sport
Purpose: This paper aims to report on empirical research that investigated the records management practices of two motor sport community-based organisations in Australia. Design/methodology/approach: This multi-method case study was conducted on the regulator of motor sport, the Confederation of Australian Motor Sport Ltd (CAMS) and one affiliated historic car club, the Vintage Sports Car Club (VSCC), in Western Australia. Data were gathered using an online audit tool and by interviewing selected stakeholders in these organisations about their organisation’s records management practices. Findings: The findings confirm that these organisations experience significant information management challenges, including difficulty in capturing, organising, managing, searching, accessing and preserving their records and archives. Hence, highlighting their inability to manage records advocated in the best practice Standard ISO 15489. It reveals the assumption of records management roles by unskilled members of the group. It emphasises that community-based organisations require assistance in managing their information management assets. Research limitations/implications: This research focused on the historic car clubs; hence, it did not include other Australian car clubs in motor sport. Although four historical car clubs, one in each Australian state, were invited to participate, only the VSCC participated. This reduced the sample size to only one CAMS-affiliated historical car club in the study. Hence, further research is required to investigate the records management practices of other CAMS affiliated car clubs in all race disciplines and to confirm whether they experienced similar information management challenges. Comments from key informants in this project indicated that this is likely the case. Practical implications: The research highlights risks to the motor sport community’s records and archives. It signals that without leadership by the sport’s governing body, current records and community archives of CAMS and its affiliated car clubs are in danger of being inaccessible, hence lost. Social implications: The research highlights the risks in preserving the continuing memory of records and archives in leisure-based community organisations and showcases the threats in preserving its cultural identity and history. Originality/value: It is the first study examining records management practices in the serious leisure sector using the motor sport community
Plasticity in dendroclimatic response across the distribution range of Aleppo pine (Pinus halepensis)
We investigated the variability of the climate-growth relationship of Aleppo pine across its distribution range in the Mediterranean Basin. We constructed a network of tree-ring index chronologies from 63 sites across the region. Correlation function analysis identified the relationships of tree-ring index to climate factors for each site. We also estimated the dominant climatic gradients of the region using principal component analysis of monthly, seasonal, and annual mean temperature and total precipitation from 1,068 climatic gridpoints. Variation in ring width index was primarily related to precipitation and secondarily to temperature. However, we found that the dendroclimatic relationship depended on the position of the site along the climatic gradient. In the southern part of the distribution range, where temperature was generally higher and precipitation lower than the regional average, reduced growth was also associated with warm and dry conditions. In the northern part, where the average temperature was lower and the precipitation more abundant than the regional average, reduced growth was associated with cool conditions. Thus, our study highlights the substantial plasticity of Aleppo pine in response to different climatic conditions. These results do not resolve the source of response variability as being due to either genetic variation in provenance, to phenotypic plasticity, or a combination of factors. However, as current growth responses to inter-annual climate variability vary spatially across existing climate gradients, future climate-growth relationships will also likely be determined by differential adaptation and/or acclimation responses to spatial climatic variation. The contribution of local adaptation and/or phenotypic plasticity across populations to the persistence of species under global warming could be decisive for prediction of climate change impacts across populations. In this sense, a more complex forest dynamics modeling approach that includes the contribution of genetic variation and phenotypic plasticity can improve the reliability of the ecological inferences derived from the climate-growth relationships.This work was partially supported by Spanish Ministry of Education and Science co-funded by FEDER program (CGL2012-31668), the European Union and the National Ministry of Education and Religion of Greece (EPEAEK- Environment – Archimedes), the Slovenian Research Agency (program P4-0015), and the USDA Forest Service. The cooperation among international partners was supported by the COST Action FP1106, STREeSS
Lymphoma cell-driven IL-16 is expressed in activated B-cell-like diffuse large Bcell lymphomas and regulates the pro-tumor microenvironment
The activated B-cell–like subtype of diffuse large B-cell lymphoma (ABC-DLBCL) displays a worse outcome than the germinal center B-cell–like subtype (GCB-DLBCL). Currently, targeting tumor microenvironment (TME) is the promising approach to cure DLBCL with profound molecular heterogeneity, however, the factors affecting the tumor-promoting TME of ABCDLBCL are elusive. Here, cytokine interleukin-16 (IL-16) is expressed in tumor cells of ABCDLBCL and secreted by the cleavage of active caspase-3. The serum IL-16 levels are not only a sensitive marker of treatment response but also positively correlated with unfavorable prognosis in DLBCL patients. While IL-16 shows few direct promotional effects on tumor cell growth in vitro, its bioactive form significantly promotes tumor progression in vivo. Mechanically, IL-16 increases the infiltration of macrophages by the chemotaxis of CD4+ monocytes in the TME enhancing angiogenesis, and the expression of cytokine IL-6 and IL-10, as well as decreasing T cell infiltration to accelerate tumor progression. This study demonstrates that IL-16 exerts a novel role in coordinating the bidirectional interactions between tumor progression and the TME. IMM0306, a fusion protein of CD20 mAb with the CD47 binding domain of SIRPα, reverses the tumorpromoting effects of IL-16,which provides new insight into treatment strategy in ABC-DLBCL
An overview of the history and development of naturopathy in South Africa
BACKGROUND: A huge growth in complementary and alternative medicine (CAM) took place in
South Africa in the 1960s which paralleled what was happening in other parts of the western
world. Naturopathy has been practised in South Africa for over 60 years, and the history of
naturopathy is entwined with the broader history of CAM. No laws existed at that stage to
regulate the curriculum, education and training of CAM practitioners. With the passage of
time, various statutes were introduced which eventually led to changes in legislation and the
establishment of a recognised training programme. Naturopathy became a legally regulated
profession, the full history of which has never been documented.
OBJECTIVE: This article explores the history of naturopathy in South Africa.
METHOD: A two-phase qualitative research design was used, consisting of a document search
and semi-structured interviews with key informants who were identified through a process of
snowballing. Information collected from the naturopaths who participated in the interviews
was triangulated with documentation uncovered in the archives of the Allied Health
Professions Council of South Africa (AHPCSA) and other literature available.
RESULTS: The result is a history of events which took place and reveals the effect of various
legislations on the profession.
CONCLUSION: Changes in the political system paved the way for changes in legislation which
allowed for the registration and training of naturopathic practitioners. However, the lack of a
functioning association and the small number of naturopathic graduates have hampered the
growth of the profession, preventing it from becoming a significant contributor to the health
care system
Isotopic evidence for dietary niche overlap between barking deer and four-horned antelope in Nepal
BACKGROUND: Morphologically similar sympatric species may have a high degree of niche overlap. Barking deer Muntiacus vaginalis and four-horned antelope Tetracerus quadricornis are solitary ungulates of the Indian sub-continent. Limited information is available regarding their trophic ecology, particularly of the endemic four-horned antelope. We present stable carbon (δ(13)C), nitrogen (δ(15)N), and sulphur (δ(34)S) isotopic values, and nitrogen content (%N) of faeces from barking deer and four-horned antelope living in lowland Nepal to assess trophic niche differentiation of these herbivores along the browser-grazer continuum. We also describe trophic differences between those two species in ecological niches and seasonal effects on their diets. RESULTS: We found that the barking deer and four-horned antelope consumed C(3) plant sources exclusively. The niche partitioning in their diet was reflected by δ(34)S values. Some seasonal effects observed were: δ(13)C and δ(15)N were significantly lower in the dry season diet of four-horned antelope than that of barking deer, while δ(34)S values were significantly higher in the winter diet; monsoon diet was similar for both species. Faecal N levels for barking deer and four-horned antelope were similar throughout all the seasons, indicating that both species adapted their feeding behaviour so as to maximize protein intake, in accordance with season and environment. CONCLUSIONS: Barking deer and four-horned antelope both are browsers; their dietary sources overlapped during monsoon but differed during the dry season. Conservation actions focused on resource management during the dry season to reduce food scarcity and competition over limited resources is likely to be the most effective. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40709-015-0029-0) contains supplementary material, which is available to authorized users
Bone histology provides insights into the life history mechanisms underlying dwarfing in hipparionins
Size shifts may be a by-product of alterations in life history traits driven by natural selection. Although this approach has been proposed for islands, it has not yet been explored in continental faunas. The trends towards size decrease experienced by some hipparionins constitute a good case study for the application of a life history framework to understand the size shifts on the continent. Here, we analysed bone microstructure to reconstruct the growth of some different-sized hipparionins from Greece and Spain. The two dwarfed lineages studied show different growth strategies. The Greek hipparions ceased growth early at a small size thus advancing maturity, whilst the slower-growing Spanish hipparion matured later at a small size. Based on predictive life history models, we suggest that high adult mortality was the likely selective force behind early maturity and associated size decrease in the Greek lineage. Conversely, we infer that resource limitation accompanied by high juvenile mortality triggered decrease in growth rate and a relative late maturity in the Spanish lineage. Our results provide evidence that different selective pressures can precipitate different changes in life history that lead to similar size shifts
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