9 research outputs found

    Aurantosides G, H, and I: Three new tetramic acid glycosides from a Papua New Guinea Theonella swinhoei.

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    Aurantosides G-I (I-III) have been isolated from the lithistid sponge Theonella swinhoei from Papua New Guinea. Their structures were established by spectroscopic and chem. methods. Compds. I-III represent new monochloropentaenoyl tetramic acids with mono-, di-, and tri-N-saccharide substituents, resp. Aurantosides G-I (I-III) failed to show any significant cytotoxicity against the human colon tumor cell line HCT-116.No Full Tex

    PI3K in lymphocyte development, differentiation and activation

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    Signaling mechanisms regulating B-lymphocyte activation and tolerance

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