Effect of temperature on the accumulation of marine biogenic gels in the surface microlayer near the outlet of nuclear power plants and adjacent areas in the Daya Bay, China

The surface microlayer (SML) in marine systems is often characterized by an enrichment of biogenic, gel-like particles, such as the polysaccharide-containing transparent exopolymer particles (TEP) and the protein-containing Coomassie stainable particles (CSP). This study investigated the distribution of TEP and CSP, in the SML and underlying water, as well as their bio-physical controlling factors in Daya Bay, an area impacted by warm discharge from two Nuclear power plants (Npp’s) and aquaculture during a research cruise in July 2014. The SML had higher proportions of cyanobacteria and of pico-size Chl a contrast to the underlayer water, particularly at the nearest outlet station characterized by higher temperature. Diatoms, dinoflagellates and chlorophyll a were depleted in the SML. Both CSP and TEP abundance and total area were enriched in the SML relative to the underlying water, with enrichment factors (EFs) of 1.5–3.4 for CSP numbers and 1.32–3.2 for TEP numbers. Although TEP and CSP showed highest concentration in the region where high productivity and high nutrient concertation were observed, EFs of gels and of dissolved organic carbon (DOC) and dissolved acidic polysaccharide (> 1 kDa), exhibited higher values near the outlet of the Npp’s than in the adjacent waters. The positive relation between EF’s of gels and temperature and the enrichment of cyanobacteria in the SML may be indicative of future conditions in a warmer ocean, suggesting potential effects on adjusting phytoplankton community, biogenic element cycling and air-sea exchange processe

High glucose up-regulates ENaC and SGK1 expression in HCD-cells

Background/Aim: Diabetic nephropathy is associated with progressive renal damage, leading to impaired function and end-stage renal failure. Secondary hypertension stems from a deranged ability of cells within the kidney to resolve and appropriately regulate sodium resorption in response to hyperglycaemia. However, the mechanisms by which glucose alters sodium re-uptake have not been fully characterised. Methods: Here we present RT-PCR, western blot and immunocytochemistry data confirming mRNA and protein expression of the serum and glucocorticoid inducible kinase (SGK1) and the a conducting subunit of the epithelial sodium channel (ENaC) in a model in vitro system of the human cortical collecting duct (HCD). We examined changes in expression of these elements in response to glucose challenge, designed to mimic hyperglycaemia associated with type 2 diabetes mellitus. Changes in Na+ concentration were assessed using single-cell microfluorimetry. Results: Incubation with glucose, the Ca2+-ionophore ionomycin and the cytokine TGF-beta 1 were all found to evoke significant and time-dependent increases in both SGK1 and alpha ENaC protein expression. These molecular changes were correlated to an increase in Na+-uptake at the single-cell level. Conclusion: Together these data offer a potential explanation for glucose-evoked Na+-resorption and a potential contributory role of SGK1 and ENaCs in development of secondary hypertension, commonly linked to diabetic nephropathy

An Updated Search of Steady TeV γ−\gamma-Ray Point Sources in Northern Hemisphere Using the Tibet Air Shower Array

Using the data taken from Tibet II High Density (HD) Array (1997 February-1999 September) and Tibet-III array (1999 November-2005 November), our previous northern sky survey for TeV $\gamma-$ray point sources has now been updated by a factor of 2.8 improved statistics. From $0.0^{\circ}$ to $60.0^{\circ}$ in declination (Dec) range, no new TeV $\gamma-$ray point sources with sufficiently high significance were identified while the well-known Crab Nebula and Mrk421 remain to be the brightest TeV $\gamma-$ray sources within the field of view of the Tibet air shower array. Based on the currently available data and at the 90% confidence level (C.L.), the flux upper limits for different power law index assumption are re-derived, which are approximately improved by 1.7 times as compared with our previous reported limits.Comment: This paper has been accepted by hepn

PENGOLAHAN DATA PENJUALAN DAN PEMBELIAN JAMU DI AGEN RESMI JAMU JAYA GUNA BREBES

Sebagaimana program – program yang sudah ada Pengolahan Datan Penjualan dan Pembelian Jamu diAgen resmi Jamu Jaya Guna Brebes adalah mengolah data – data penjualan dan pembelian yang ada pada Agen resmi Jamu Jaya Guna di mana pada Pengolahan data tersebut mengatur tentang jumlah pengeluaran barang (Stock, Sachet, Tablet) yang dikeluar oleh pabrik jamu Jaya Guna Brebes untuk di hitung supaya dijadikan bahan pertimbangan bagi sebuah perusahaan. Dalam Pengolahan data Penjualan dan Pembelian Jamu di Agen resmi Jaya Guna Brebes Dalam suatu perusahaan besar ataupun kecil yang bergerak di bidang pemasaran, masalah yang termasuk paling penting yang harus ditangani adalah pengolahan data transaksi penjualan dan pembelian. Oleh karena itu, maka kedua transaksi itu haruslah menjadi prioritas utama dalam penanganannya. Sehingga tidak terjadi kesalahan yang akan merusak jalannya usaha dari perusahaan tersebut

Kernel Architecture of the Genetic Circuitry of the Arabidopsis Circadian System

A wide range of organisms features molecular machines, circadian clocks, which generate endogenous oscillations with ~24 h periodicity and thereby synchronize biological processes to diurnal environmental fluctuations. Recently, it has become clear that plants harbor more complex gene regulatory circuits within the core circadian clocks than other organisms, inspiring a fundamental question: are all these regulatory interactions between clock genes equally crucial for the establishment and maintenance of circadian rhythms? Our mechanistic simulation for Arabidopsis thaliana demonstrates that at least half of the total regulatory interactions must be present to express the circadian molecular profiles observed in wild-type plants. A set of those essential interactions is called herein a kernel of the circadian system. The kernel structure unbiasedly reveals four interlocked negative feedback loops contributing to circadian rhythms, and three feedback loops among them drive the autonomous oscillation itself. Strikingly, the kernel structure, as well as the whole clock circuitry, is overwhelmingly composed of inhibitory, rather than activating, interactions between genes. We found that this tendency underlies plant circadian molecular profiles which often exhibit sharply-shaped, cuspidate waveforms. Through the generation of these cuspidate profiles, inhibitory interactions may facilitate the global coordination of temporally-distant clock events that are markedly peaked at very specific times of day. Our systematic approach resulting in experimentally-testable predictions provides insights into a design principle of biological clockwork, with implications for synthetic biology.Comment: Supplementary material is available at the journal websit

Generalized trigonometric interpolation

This article proposes a generalization of the Fourier interpolation formula, where a wider range of the basic trigonometric functions is considered. The extension of the procedure is done in two ways: adding an exponent to the maps involved, and considering a family of fractal functions that contains the standard case. The studied interpolation converges for every continuous function, for a large range of the nodal mappings chosen. The error of interpolation is bounded in two ways: one theorem studies the convergence for Hölder continuous functions and other develops the case of merely continuous maps. The stability of the approximation procedure is proved as well

Quantum Griffiths singularity in three-dimensional MoTiN superconducting films

Quantum Griffiths singularity (QGS) has been experimentally observed in a range of two-dimensional (2D) superconducting systems. Although it is theoretically suggested that the QGS also exists in three-dimensional (3D) superconductors, there is almost no experimental support to the theoretical prediction. In the present paper, we observe the occurrence of QGS in a series of $\sim$80-nm-thick Mo$_{0.8}$Ti$_{0.2}$N$_x$ ($0.84 \lesssim x \lesssim 1.12$) superconducting films near the field-driven superconductor-metal transition (SMT). These films have a NaCl structure and are 3D with respect to the superconductivity. For each film, the low-temperature magnetoresistance isotherms, measured at magnetic fields being perpendicular or parallel to the film plane, do not cross at a single point but at a clear wide region. The dynamical critical exponents $z\nu_{\perp}$ (for perpendicular field) and $z\nu_{\parallel}$ (for parallel field) obtained by analyzing the related magnetoresistance isotherms increase with decreasing temperature and tend to diverge as $T\rightarrow 0$ K. In addition, the effective resistivity data for the perpendicular and parallel field in the vicinity of the SMTs both obey an activated scaling based on the random transverse-field Ising model. We also fabricate a $\sim$80-nm-thick (Mo$_{0.8}$Ti$_{0.2}$)$_2$N$_{1.06}$ superconducting film with face-centered cubic structure at low nitrogen partial pressure. It is found that the low-temperature magnetoresistance isotherms for the perpendicular (parallel) field cross at a single point and the resistivity data for the perpendicular (parallel) field in the vicinity of the field-induced SMT obey the power-law scaling deduced from the dirty-boson model. Our results provide unambigous experimental evidence for the existence of QGS in 3D superconductors.Comment: 11 pages and 9 Figure

Frequency-Synthesized Approach to High-Power Attosecond Pulse Generation and Applications: Generation and Diagnostics

We present a new scheme of generating high-power attosecond pulses and arbitrary waveform synthesis by multicolor synthesis. The full bandwidth of the multicolor laser system extends more than two-octaves and reaches 37,600 cm−1 which can be used to generate sub-single-cycle (∼0.37 cycle) sub-femtosecond (360 attosecond) pulses with carrier-envelope phase (CEP) control. The results show a promising approach for generation of relatively high-power attosecond pulses in the optical region. In this chapter, the design and diagnostics of the laser system are described. In part 2 of this work (the following chapter), we demonstrate selected applications of this novel source, such as coherently controlled harmonic generation as well as phase-sensitive 2-color ablation of copper and stainless steel by this multi-color laser system