59 research outputs found
KIR/HLA genotype combinations are determinants of Natural Killer (NK) cell mediated antibody-dependent cellular cytotoxicity (ADCC) potency
Are the KIR3DS1homozygous and KIR3DL1*h/*y+HLA-B*57 genotypes associated protection from HIV by different routes of exposure?
KIR/HLA genotype combinations are determinants of Natural Killer (NK) cell mediated antibody-dependent cellular cytotoxicity (ADCC) potency
The Inclusiveness and Emptiness of <i>Gong Qi</i>: A Non-Anglophone Perspective on Ethics from a Sino-Japanese Corporation
This article introduces a non-Anglophone concept of gong qi(communal vessel, 公器) as a metaphor for ‘corporation’. It contributes an endogenous perspective from a Sino-Japanese organizational context that enriches mainstream business ethics literature, otherwise heavily reliant on Western traditions. We translate the multi-layered meanings of gong qi based on analysis of its ideograms, its references into classical philosophies, and contemporary application in this Japanese multinational corporation in China. Gong qi contributes a perspective that sees a corporation as an inclusive and virtuous social entity, and also addresses the elusive, implicit, and forever evolving nature of organizational life that is rarely noticed. We propose gong qi can be applied in other organizations and wider cultural contexts to show a new way of seeing and understanding business ethics and organization. Rather than considering virtue as a list of definable individual qualities, we suggest that the metaphor of gong qi reveals how virtue can be experienced as indeterminate, yet immanently present, like the substance of emptiness. This, then allows us to see the virtue of immanence, the beauty of implicitness, and hence, the efficacy of gong qi
Management of Knowledge, Information and Organizational Learning in University Libraries
Identifying factors increasing the risk of acquiring HIV among Egyptians to construct a consensus web-based tool for HIV risk assessment
A receptor theory-based semimechanistic PD model for the CCR5 noncompetitive antagonist maraviroc
Use of a Mouth Gag Instrument to Facilitate Bite Block Insertion and Prevent Finger and Probe Bites During Transesophageal Echocardiography
The Italian quality control study for evaluation of CD4 cells in centres involved in the treatment of HIV-1 patients
We report on the experience of establishing a national network for a quality control programme in evaluating CD4 cell counts in most Italian centres involved in the care of patients with HIV disease. The 68 centres were divided according to their geographical location into eight groups, and twice a year (tests A and B) they received three coded whole blood samples (two were replicates of the same sample) obtained from two informed HIV+ patients, one with CD4 counts/mm3 expected to be < 200 and one with values > 300. The medians of the determinations performed by the labs involved in each of the eight areas were taken as the ‘true’ values for each sample. Unsatisfactory performances for percentage of CD4 cells were identified as a CD4 analysis with residual values ≥ ± 5% and with deviates ≥ ± 2. For absolute numbers of CD4 cells, an unsatisfactory performance was defined as CD4 counts with residual > ± 100 CD4 cells/mm3 and with deviates ≥ ± 2. The residual value is the CD4 value reported by each lab minus the median value. The deviate is the residual divided by the modified interquartile range (IQR × 0.75). Most of the centres provided reliable results. However, some labs failed to provide satisfactory results for percentages (6.25% of the tested labs for test A and 6.17% for test B) or absolute numbers (16.25% test A and 12.34% test B). Only 3.7% of the labs gave unsatisfactory results in both tests. Four of the unsatisfactory results from the two tests gave an error in absolute numbers > ± 200 CD4 cells/mm3. Our data suggest that most Italian labs provide reliable results in evaluating the numbers of CD4 cells in HIV-1+ samples, but the importance of running a quality control programme is highlighted by our experience with those centres which provide unsatisfactory data which may lead to incorrect classification of the patients or assessment of treatment
Large Unstained Cells: A Potentially Valuable Parameter in the Assessment of Immune Activation Levels in HIV Infection
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