The effects of graded motor imagery and its components on chronic pain: A systematic review and meta-analysis

This is the post-print version of the final paper published in The Journal of Pain. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. Copyright @ 2013 The American Pain Society.Graded motor imagery (GMI) is becoming increasingly used in the treatment of chronic pain conditions. The objective of this systematic review was to synthesize all evidence concerning the effects of GMI and its constituent components on chronic pain. Systematic searches were conducted in 10 electronic databases. All randomized controlled trials (RCTs) of GMI, left/right judgment training, motor imagery, and mirror therapy used as a treatment for chronic pain were included. Methodological quality was assessed using the Cochrane risk of bias tool. Six RCTs met our inclusion criteria, and the methodological quality was generally low. No effect was seen for left/right judgment training, and conflicting results were found for motor imagery used as stand-alone techniques, but positive effects were observed for both mirror therapy and GMI. A meta-analysis of GMI versus usual physiotherapy care favored GMI in reducing pain (2 studies, n = 63; effect size, 1.06 [95% confidence interval, .41, 1.71]; heterogeneity, I2 = 15%). Our results suggest that GMI and mirror therapy alone may be effective, although this conclusion is based on limited evidence. Further rigorous studies are needed to investigate the effects of GMI and its components on a wider chronic pain population.NHMR

The Phonological Process with Two Patterns of Simplified Chinese Characters

This paper analyzed word recognition in two patterns of Chinese characters, cross referenced with word frequency. The patterns were defined as uni-part (semantic radical/component only) and bi-part (including the phonetic radical/component and the semantic radical/component) characters. The interactions of semantic and phonological access in both patterns were inspected. It was observed that in the naming task and the pronunciation-matching task, the subject performance involving the uni-part characters showed longer RT than the bi-part characters. However, with the lexical decision and meaning-matching tasks the uni-part characters showed shorter RT than the bi-part characters. It was also observed that the frequency, which is regarded as a lexical variable, displayed a strong influence. This suggests that Chinese characters require lexical access in all tasks. This study also suggested that the phonological process is primary in visual word recognition; as there is a significant phonological effect in processing the Chinese bi-part characters, resulting in either the facilitation or inhibition of phonology due to the differing demands of the two task

Calls to a home birth helpline: empowerment in childbirth

In the UK a woman has the right to decide to give birth at home, irrespective of whether she is expecting her first or a subsequent child and of any perceived ‘risk’ factors. However, the rate of home births in the UK is very low (around 2%), varies widely across the country and many women do not know how to arrange midwifery cover. The Home Birth helpline is a UK-based voluntary organisation offering support and information for women planning a home birth. In order to gain direct access to the issues that are of concern to women when planning a home birth, 80 calls to the helpline were recorded. The aims of this paper are to document the problems that callers to this helpline report having when trying to arrange home births and to explore the strategies the call-taker uses in helping women to exercise their right to birth at home. The paper concludes that women are not easily able to exercise their right to choose the place of birth and suggests a number of recommendations for action

Too little, too late: reduced visual span and speed characterize pure alexia

Whether normal word reading includes a stage of visual processing selectively dedicated to word or letter recognition is highly debated. Characterizing pure alexia, a seemingly selective disorder of reading, has been central to this debate. Two main theories claim either that 1) Pure alexia is caused by damage to a reading specific brain region in the left fusiform gyrus or 2) Pure alexia results from a general visual impairment that may particularly affect simultaneous processing of multiple items. We tested these competing theories in 4 patients with pure alexia using sensitive psychophysical measures and mathematical modeling. Recognition of single letters and digits in the central visual field was impaired in all patients. Visual apprehension span was also reduced for both letters and digits in all patients. The only cortical region lesioned across all 4 patients was the left fusiform gyrus, indicating that this region subserves a function broader than letter or word identification. We suggest that a seemingly pure disorder of reading can arise due to a general reduction of visual speed and span, and explain why this has a disproportionate impact on word reading while recognition of other visual stimuli are less obviously affected

Just-In-Time/Just-In-Case Inventory Management as an Influence on Supply Chain Disruption in Medical Systems Based in the Southeastern United States During the COVID-19 Pandemic

The purpose of this quantitative study was to gain a deeper understanding on the impact that the COVID-19 pandemic had on the global supply chain, particularly in the southeastern region of the United States. The study involved a population comprised of professionals employed in medical systems who possessed a working knowledge of supply chain management. The researcher distributed online surveys via an online survey platform to a list of medical systems professionals in both the public and private sectors. The sample size was 396 professionals, and the number of respondents was 201, once the prospective research participants were properly vetted. The data were analyzed using an array of statistical techniques, including Spearman’s rho technique and Pearson’s r. The dependent variable PPE and the corresponding independent variables were just-in-time and just-in-case inventory management approaches. The researcher conducted a power analysis to determine the strength of the association between the dependent variable PPE and the independent variables JIT and JIC, as well as the mediating variable COVID-19. The two-sided test was performed based on Fisher\u27s z-transformation, with a typical approximation inclusive of a bias adjustment. Recommendations for further research include developing an enhanced supply chain management system. Four points worth considering for further research include a) research participants; (b) geographic location; (c) selection of medical commodities; and (d) timing of the study

Simultanagnosia: When a Rose Is Not Red

Information regarding object identity (‘‘what’’) and spatial location (‘‘where/how to’’) is largely segregated in visual processing. Under most circumstances, however, object identity and location are linked. We report data from a simultanagnosic patient (K.E.) with bilateral posterior parietal infarcts who was unable to ‘‘see’’ more than one object in an array despite relatively preserved object processing and normal preattentive processing. K.E. also demonstrated a finding that has not, to our knowledge, been reported: He was unable to report more than one attribute of a single object. For example, he was unable to name the color of the ink in which words were written despite naming the word correctly. Several experiments demonstrated, however, that perceptual attributes that he was unable to report influenced his performance. We suggest that binding of object identity and location is a limited-capacity operation that is essential for conscious awareness for which the posterior parietal lobe is crucial

Increasing Distance Instruction Through Electronic Newsletters

This poster details the new outreach method we utilized to increase our bibliographic instruction sessions with the distributed Brandman campuses served by the Chapman Leatherby Libraries. The use of our new electronic newsletter increased the amount of bibliographic instruction sessions that we performed during the 2017-18 year

Dissociable Neural Systems for Timing: Evidence from Subjects with Basal Ganglia Lesions

Background: The neural basis of timing remains poorly understood. Although controversy persists, many lines of evidence, including studies in animals, functional imaging studies in humans and lesion studies in humans and animals suggest that the basal ganglia are important for temporal processing [1]. Methodology/Principal Findings: We report data from a wide range of timing tasks from two subjects with disabling neurologic deficits caused by bilateral lesions of the basal ganglia. Both subjects perform well on tasks assessing time estimation, reproduction and production tasks. Additionally, one subject performed normally on psychophysical tasks requiring the comparison of time intervals ranging from milliseconds to seconds; the second subject performed abnormally on the psychophysical task with a 300ms standard but did well with 600ms, 2000ms and 8000ms standards. Both subjects performed poorly on an isochronous rhythm production task on which they are required to maintain rhythmic tapping. Conclusions/Significance: As studies of subjects with brain lesions permit strong inferences regarding the necessity of brain structures, these data demonstrate that the basal ganglia are not crucial for many sub- or supra-second timing operations in humans but are needed for the timing procedures that underlie the production of movements. This dissociation suggests that distinct and dissociable processes may be employed to measure time intervals. Inconsistencies in findings regarding the neural basis of timing may reflect the availability of multiple temporal processing routines that are flexibly implemente

Observed bodies generate object-based spatial codes

Contemporary studies of spatial and social cognition frequently use human figures as stimuli. The interpretation of such studies may be complicated by spatial compatibility effects that emerge when researchers employ spatial responses, and participants spontaneously code spatial relationships about an observed body. Yet, the nature of these spatial codes – whether they are location- or object-based, and coded from the perspective of the observer or the figure – has not been determined. Here, we investigated this issue by exploring spatial compatibility effects arising for objects held by a visually presented whole-bodied schematic human figure. In three experiments, participants responded to the colour of the object held in the figure’s left or right hand, using left or right key presses. Left-right compatibility effects were found relative to the participant’s egocentric perspective, rather than the figure’s. These effects occurred even when the figure was rotated by 90 degrees to the left or to the right, and the coloured objects were aligned with the participant’s midline. These findings are consistent with spontaneous spatial coding from the participant’s perspective and relative to the normal upright orientation of the body. This evidence for object-based spatial coding implies that the domain general cognitive mechanisms that result in spatial compatibility effects may contribute to certain spatial perspective-taking and social cognition phenomena