Vestibular Facilitation of Optic Flow Parsing

Simultaneous object motion and self-motion give rise to complex patterns of retinal image motion. In order to estimate object motion accurately, the brain must parse this complex retinal motion into self-motion and object motion components. Although this computational problem can be solved, in principle, through purely visual mechanisms, extra-retinal information that arises from the vestibular system during self-motion may also play an important role. Here we investigate whether combining vestibular and visual self-motion information improves the precision of object motion estimates. Subjects were asked to discriminate the direction of object motion in the presence of simultaneous self-motion, depicted either by visual cues alone (i.e. optic flow) or by combined visual/vestibular stimuli. We report a small but significant improvement in object motion discrimination thresholds with the addition of vestibular cues. This improvement was greatest for eccentric heading directions and negligible for forward movement, a finding that could reflect increased relative reliability of vestibular versus visual cues for eccentric heading directions. Overall, these results are consistent with the hypothesis that vestibular inputs can help parse retinal image motion into self-motion and object motion components

Serotonin and GI Disorders: An Update on Clinical and Experimental Studies

The gastrointestinal (GI) tract is the largest producer of serotonin (5-hydroxytryptamine (5-HT)) in the body, and as such it is intimately connected with GI function and physiology. 5-HT produced by enterochromaffin (EC) cells is an important enteric mucosal signaling molecule and has been implicated in a number of GI diseases, including inflammatory bowel disease and functional disorders such as irritable bowel syndrome. This review will focus on what is known of basic 5-HT physiology and also on the emerging evidence for its novel role in activation of immune response and inflammation in the gut. Utilizing pubmed.gov, search terms such as “5-HT,” “EC cell,” and “colitis,” as well as pertinent reviews, were used to develop a brief overview of EC cell biology and the association between 5-HT and various GI disorders. It is the aim of this review to provide the readers with an update on EC cell biology and current understanding on the role of 5-HT in GI disorders specifically in inflammatory conditions

Attachment states of mind and couple relationships in couples seeking to adopt

We present the results of a study carried out in Italy with 39 Italian couples seeking to adopt, aged between 35 and 45 years, and 39 matched non-adoptive couples which compared their attachment states of mind with respect to caregivers and partners and quality of couple relationship. Both partners of the couples completed individually measures of attachment to caregiver (Adult Attachment Interview; AAI), attachment to partner (Current Relationship Interview; CRI and Experiences in Close Relationships Scale-Revised; ECR-R) and marital quality (Dyadic Adjustment Scale; DAS). The results showed that couples seeking to adopt did not differ from the control group with respect to attachment to caregivers (AAI). However potential adoptive fathers were more likely to show secure attachment classifications with respect to partner (CRI) than non-adoptive fathers. Finally, couples seeking to adopt expressed higher levels of positive feelings and thoughts within the couple relationship (ECR-R) and better perceived quality of marital relationship (DAS) than the control group. Overall, these findings suggested that couples seeking to adopt placed a high value on attachment relationships, which is considered a relevant factor for positive outcome of adoption