Medical hypothesis: can gonadotropins influence thyroid volume in women with PCOS?

It has been reported that luteinizing hormone (LH) had thyropropic effect on rat and human thyroid membrane. It has been known that patients with PCOS have elevated LH levels in comparison to healthy controls. The goiter prevalence is more common in women than in men regardless of population. The higher incidence of thyroid diseases in women has been previously attributed to higher estradiol levels. Estradiol has been shown to enhance proliferative and mitogenic activities of thyroid cells. However, in recent years chronic estradiol treatment has been shown to reduce volume densities of thyroid follicles, follicular epithelium and thyroid gland volume. It is thought to be due to LH suppression. Therefore we suggested that increased LH levels might provide a stimulus for growth on thyroid and alter thyroid function. Therefore patients with PCOS who had elevated LH levels should be treated by combined estradiol pills such as estrogen-progestin contraceptives for suppression of LH secretion. Further studies are needed to evaluate the association between LH, LH suppression and thyroid volume in patients with PCOS

Perception, practice and proximity. Qualifying threats as psychological torture in international law.

Background: Fear is a central dimension of torture and cruel, inhuman and degrading treatment (hereafter ‘other ill-treatment’), particularly as a part of verbal or non-verbal threats. Adjudicators and policy-makers have grappled, arguably at a greater depth than with other methods of psychological torture, with the circumstances in which fear-based methods amount to torture or other ill-treatment. The pursuit of non-coercive standards of police interrogation has further underscored the need to better distinguish the prohibited from the permitted. Upon this background, this article reviews the existing jurisprudential and social scientific literature in formulating a lens through which fear-inducing methods could be better functionally conceptualised. Method: This article has identified, through systematic full-text search of databases, texts with keywords ‘threat’, ‘fear’, ‘coercion’, ‘intimidation’, ‘distress’, ‘anguish’ and ‘psychological pressure’. The identified texts, limited to English-language journal articles, NGO reports, court-cases and UN documents from 1950 to date, were then selected for relevance pertaining to conceptual, evidentiary and legal critique provided therein. Discussion: Whilst it is broadly recognized that the deployment of fear to inflict violence can amount to torture, methods of threats or coercion are not adequately conceptualized particularly at the lower end, i.e. routine interrogational torture. Here, principles pertaining to the legitimate use of force and minimum level of severity are used as functional guidelines to distinguish the prohibited from the permitted. The power, practice and proximity of state authorities to harm necessarily qualify threats as real, immediate and credible and therefore torturous

Debility, dependency and dread: On the conceptual and evidentiary dimensions of psychological torture

Background: Psychological torture is deployed to break and obliterate human resistance, spirit and personality, but it is rarely afforded sufficient attention. Deficiencies in conceptualising, documenting and adjudicating non-physical torture mean that it is frequently left undetected and uncontested by the public, media and the courts, bolstering impunity for its perpetrators. A review of the current literature to map conceptual and evidentiary shortcomings from an inter-disciplinary perspective is therefore warranted. Method: The relevant texts were identified through a systematic full-text search of databases, namely HeinOnline, HUDOC, UNODS and DIGNITY´s Documentation Centre, with the keywords `psychological torture´, `mental pain and suffering´, `severity´, `humiliation´, `interrogation techniques´, and `torture methods´. The identified texts, limited to English-language journal articles, NGO reports, court-cases and UN documents from 1950 to date, were then selected for relevance pertaining to conceptual, evidentiary, technological and ethical critique provided therein. Results/Discussion: Evidential invisibility, subjectivity of the suffering, and perceived technological control are the primary ways in which psychological torture methods are designed, and how they manage to evade prosecution and consequently be perpetuated. Cognisant of the need for further research, pertinent questions highlighting the need to develop approaches, sharpen standards and use a medical/psychological/legal interdisciplinary approach are suggested

Contact, Political Solidarity and Collective Action: An Indian Case Study of Relations between Historically Disadvantaged Communities

Research on the contact hypothesis has highlighted the role of contact in improving intergroup relations. Most of this research has addressed the problem of transforming the prejudices of historically advantaged communities, thereby eroding wider patterns of discrimination and inequality. In the present research, drawing on evidence from a cross-sectional survey conducted in New Delhi, we explored an alternative process through which contact may promote social change, namely by fostering political solidarity and empowerment amongst the disadvantaged. The results indicated that Muslim studentsˈ experiences of contact with other disadvantaged communities were associated with their willingness to participate in joint collective action to reduce shared inequalities. This relationship was mediated by perceptions of collective efficacy and shared historical grievances and moderated by positive experiences of contact with the Hindu majority. Implications for recent debates about the relationship between contact and social change are discussed

Preoperative detection of insulinomas: two case reports

This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens

THE EFFECTS OF MACROECONOMIC AND FINANCIAL DEVELOPMENT ON INCOME INEQUALITY: EVIDENCE FROM THE WESTERN BALKANS

Using data from 1996 to 2019 covering five Western Balkan countries and applying the linear panel data estimation method, this paper examines the effect of macroeconomic indicators and financial market development on income inequality. Regression results with Driscoll-Kraay standard errors demonstrate that income per capita increases income disparities. Theoretically, there are grounds for both a positive and negative relationship between economic growth and income inequality. In addition, contrary to prevailing literature, our analysis finds no significant impact of financial market development on income inequality, while the rule of law is found to have no effect on income inequalities in these countries. We depart from previous literature by bringing new evidence on the relationship between income inequality and economic growth in the specific context of Western Balkan countries. We study this relationship in an integrated framework and rely on a larger time span, both of which are seemingly important for comprehending the income inequality-economic growth nexus. Certainly, the obtained results bear important policy implications as discussed in this paper

Why people vote for thin-centred ideology parties? A multi-level multi-country test of individual and aggregate level predictors.

The present research investigates the individual and aggregate level determinants of support for thin-centred ideology parties across 23 European countries. Employing a multilevel modelling approach, we analysed European Social Survey data round 7 2014 (N = 44000). Our findings show that stronger identification with one's country and confidence in one's ability to influence the politics positively but perceiving the system as satisfactory and responsive; trusting the institutions and people, and having positive attitudes toward minorities, i.e., immigrants and refugees, negatively predict support for populist and single issue parties. The level of human development and perceptions of corruption at the country level moderate these effects. Thus, we provide the first evidence that the populist surge is triggered by populist actors' capacity to simultaneously invoke vertical, "ordinary" people against "the elites", and horizontal, "us" against "threatening aliens", categories of people as well as the sovereignty of majority over minorities. These categories and underlying social psychological processes of confidence, trust, and threats are moderated by the general level of human development and corruption perceptions in a country. It is, therefore, likely that voting for populist parties will increase as the liberally democratic countries continue to prosper and offer better opportunities for human development. Stronger emphasis on safeguarding the integrity of the economic and democratic institutions, as our findings imply, and preserving their ethical and honest, i.e., un-corrupt, nature can keep this surge under check