Oral Health Intervention: A Multifaceted Approach to Improve Oral Health Care during Pregnancy

Introduction: Early Childhood Caries (ECC) is the most common chronic disease of childhood Mothers’ oral health status is a strong predictor of the oral health status of their children 2009: Vermont spends $2.7 million treating children ages 0-5 with Early Childhood Caries 2012: Vermont lifts the$495 Medicaid cap on reimbursement for a woman’s dental care during pregnancy and up to 60 days after delivery American College of Obstetrics and Gynecology (ACOG) Guidelines on prenatal dental care are published 2013: 74% of surveyed Vermont providers treating pregnant women are unaware of the Medicaid change 82% of these providers are not using guidelines to assess oral health during pregnancy Objective: To improve prenatal dental referral rates from obstetric providers by facilitating Vermont-specific implementation of ACOG guidelineshttps://scholarworks.uvm.edu/comphp_gallery/1212/thumbnail.jp

Transcript-indexed ATAC-seq for precision immune profiling.

T cells create vast amounts of diversity in the genes that encode their T cell receptors (TCRs), which enables individual clones to recognize specific peptide-major histocompatibility complex (MHC) ligands. Here we combined sequencing of the TCR-encoding genes with assay for transposase-accessible chromatin with sequencing (ATAC-seq) analysis at the single-cell level to provide information on the TCR specificity and epigenomic state of individual T cells. By using this approach, termed transcript-indexed ATAC-seq (T-ATAC-seq), we identified epigenomic signatures in immortalized leukemic T cells, primary human T cells from healthy volunteers and primary leukemic T cells from patient samples. In peripheral blood CD4+ T cells from healthy individuals, we identified cis and trans regulators of naive and memory T cell states and found substantial heterogeneity in surface-marker-defined T cell populations. In patients with a leukemic form of cutaneous T cell lymphoma, T-ATAC-seq enabled identification of leukemic and nonleukemic regulatory pathways in T cells from the same individual by allowing separation of the signals that arose from the malignant clone from the background T cell noise. Thus, T-ATAC-seq is a new tool that enables analysis of epigenomic landscapes in clonal T cells and should be valuable for studies of T cell malignancy, immunity and immunotherapy

Lunar Operating Surface Transport

The Lunar Operating Surface Transport (LOST) is a modular unit designed to support future Artemis missions. Lunar surface operations are expanding and will require systems to support the buildup of equipment and outposts. The Lunar transport is an on-ground vehicle capable of moving dense loads for extended durations across the moon’s lunar south pole. The transport can traverse the technically challenging terrain while ensuring control and stability of the payload. The Lunar Operating Surface Transport will push the boundaries of lunar exploration and enhance operational capabilities of the Artemis program

1983: Abilene Christian College Bible Lectures - Full Text

LIGHTS IN A WORLD OF DARKNESS Being the Abilene Christian University Annual Bible Lectures 1983 Published by Abilene Christian University Book Store ACU Station Abilene, Texas 7969

Effect of Detector Coincidence Criteria on a High Precision Measurement of the Neutron Lifetime

The UCNtau collaboration is working to measure the mean lifetime of a free neutron to 0.1s using very low energy “ultracold” neutrons (UCN). Achieving such high precision is important in a variety of low-energy tests for new physics. A density of UCN is produced in the Los Alamos solid-D2 super-thermal source and is then polarized and guided to a magneto-gravitational trap. The UCN that have high enough energy to escape the trapping potential are cleaned out, and the remaining neutrons are left to decay for two time intervals, a short and long holding time. The difference in the two holding times, along with the normalized number of neutrons left in the trap at the end of the holding periods, are used to calculate the average lifetime of the neutrons in the trap. The neutrons are detected using a newly-developed in situ active detector that observes light from a B-coated ZnS scintillation screen via a pair of photomultiplier tubes . Over the past year I have been doing an in depth analysis of the 2015-2016 data set and will present preliminary blinded results from my ongoing analysis

System Engineering Paper

The Iowa State University team, Team LunaCY, is composed of the following sub-teams: the main student organization, the Lunabotics Club; a senior mechanical engineering design course, ME 415; a senior multidisciplinary design course, ENGR 466; and a senior design course from Wartburg College in Waverly, Iowa. Team LunaCY designed and fabricated ART-E III, Astra Robotic Tractor- Excavator the Third, for the team's third appearance in the NASA Lunabotic Mining competition. While designing ART-E III, the team had four main goals for this year's competition:to reduce the total weight of the robot, to increase the amount of regolith simulant mined, to reduce dust, and to make ART-E III autonomous. After many designs and research, a final robot design was chosen that obtained all four goals of Team LunaCY. A few changes Team LunaCY made this year was to go to the electrical, computer, and software engineering club fest at Iowa State University to recruit engineering students to accomplish the task of making ART-E III autonomous. Team LunaCY chose to use LabView to program the robot and various sensors were installed to measure the distance between the robot and the surroundings to allow ART-E III to maneuver autonomously. Team LunaCY also built a testing arena to test prototypes and ART-E III in. To best replicate the competition arena at the Kennedy Space Center, a regolith simulant was made from sand, QuickCrete, and fly ash to cover the floor of the arena. Team LunaCY also installed fans to allow ventilation in the arena and used proper safety attire when working in the arena . With the additional practice in the testing arena and innovative robot design, Team LunaCY expects to make a strong appearance at the 2012 NASA Lunabotic Mining Competition.

Temporal Patterns of Diversification across Global Cichlid Biodiversity (Acanthomorpha: Cichlidae)

The contrasting distribution of species diversity across the major lineages of cichlids makes them an ideal group for investigating macroevolutionary processes. In this study, we investigate whether different rates of diversification may explain the disparity in species richness across cichlid lineages globally. We present the most taxonomically robust time-calibrated hypothesis of cichlid evolutionary relationships to date. We then utilize this temporal framework to investigate whether both species-rich and depauperate lineages are associated with rapid shifts in diversification rates and if exceptional species richness can be explained by clade age alone. A single significant rapid rate shift increase is detected within the evolutionary history of the African subfamily Pseudocrenilabrinae, which includes the haplochromins of the East African Great Lakes. Several lineages from the subfamilies Pseudocrenilabrinae (Australotilapiini, Oreochromini) and Cichlinae (Heroini) exhibit exceptional species richness given their clade age, a net rate of diversification, and relative rates of extinction, indicating that clade age alone is not a sufficient explanation for their increased diversity. Our results indicate that the Neotropical Cichlinae includes lineages that have not experienced a significant rapid burst in diversification when compared to certain African lineages (rift lake). Neotropical cichlids have remained comparatively understudied with regard to macroevolutionary patterns relative to African lineages, and our results indicate that of Neotropical lineages, the tribe Heroini may have an elevated rate of diversification in contrast to other Neotropical cichlids. These findings provide insight into our understanding of the diversification patterns across taxonomically disparate lineages in this diverse clade of freshwater fishes and one of the most species-rich families of vertebrates.This work was supported by NSF grants DEB 0716155, DEB 0732642, and DEB 1060869 to WLS, DEB 0910081 to MPD, DEB 0916695 to PC, DEB 1258141 to MPD and WLS, DEB 1311408 to CDM, and IOS 0749943 to JSS. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

The Fourteenth Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the extended Baryon Oscillation Spectroscopic Survey and from the second phase of the Apache Point Observatory Galactic Evolution Experiment

The fourth generation of the Sloan Digital Sky Survey (SDSS-IV) has been in operation since July 2014. This paper describes the second data release from this phase, and the fourteenth from SDSS overall (making this, Data Release Fourteen or DR14). This release makes public data taken by SDSS-IV in its first two years of operation (July 2014-2016). Like all previous SDSS releases, DR14 is cumulative, including the most recent reductions and calibrations of all data taken by SDSS since the first phase began operations in 2000. New in DR14 is the first public release of data from the extended Baryon Oscillation Spectroscopic Survey (eBOSS); the first data from the second phase of the Apache Point Observatory (APO) Galactic Evolution Experiment (APOGEE-2), including stellar parameter estimates from an innovative data driven machine learning algorithm known as "The Cannon"; and almost twice as many data cubes from the Mapping Nearby Galaxies at APO (MaNGA) survey as were in the previous release (N = 2812 in total). This paper describes the location and format of the publicly available data from SDSS-IV surveys. We provide references to the important technical papers describing how these data have been taken (both targeting and observation details) and processed for scientific use. The SDSS website (www.sdss.org) has been updated for this release, and provides links to data downloads, as well as tutorials and examples of data use. SDSS-IV is planning to continue to collect astronomical data until 2020, and will be followed by SDSS-V.Comment: SDSS-IV collaboration alphabetical author data release paper. DR14 happened on 31st July 2017. 19 pages, 5 figures. Accepted by ApJS on 28th Nov 2017 (this is the "post-print" and "post-proofs" version; minor corrections only from v1, and most of errors found in proofs corrected