Fault detection in operating helicopter drive train components based on support vector data description

The objective of the paper is to develop a vibration-based automated procedure dealing with early detection of mechanical degradation of helicopter drive train components using Health and Usage Monitoring Systems (HUMS) data. An anomaly-detection method devoted to the quantification of the degree of deviation of the mechanical state of a component from its nominal condition is developed. This method is based on an Anomaly Score (AS) formed by a combination of a set of statistical features correlated with specific damages, also known as Condition Indicators (CI), thus the operational variability is implicitly included in the model through the CI correlation. The problem of fault detection is then recast as a one-class classification problem in the space spanned by a set of CI, with the aim of a global differentiation between normal and anomalous observations, respectively related to healthy and supposedly faulty components. In this paper, a procedure based on an efficient one-class classification method that does not require any assumption on the data distribution, is used. The core of such an approach is the Support Vector Data Description (SVDD), that allows an efficient data description without the need of a significant amount of statistical data. Several analyses have been carried out in order to validate the proposed procedure, using flight vibration data collected from a H135, formerly known as EC135, servicing helicopter, for which micro-pitting damage on a gear was detected by HUMS and assessed through visual inspection. The capability of the proposed approach of providing better trade-off between false alarm rates and missed detection rates with respect to individual CI and to the AS obtained assuming jointly-Gaussian-distributed CI has been also analysed

Is Cosmology Compatible with Blue Gravity Waves ?

A primordial gravitational wave background with positive(blue) spectral index is expected in several non-standard inflationary cosmologies where the stress-energy tensor violates the null energy condition. Here we show that a sizable amount of blue gravitational waves is compatible with current cosmological and astrophysical data. So far most of the works on parameter estimation from cosmic microwave background data have assumed a negative or negligible spectral index. The present limits on cosmological parameters, especially on the scalar spectral index, widen up considerably when one allows also for blue tilts of the tensor spectrum. Since the amplitude of the CMB B-mode polarization is larger in these models, future data from Planck are likely to provide crucial measurements.Comment: 5 Pages, 5 Figure

The ππ\pi\pi interaction in nuclear matter from a study of the π+A→π+π±A′\pi^+ A \to \pi^+ \pi^{\pm} A' reactions

The pion-production reactions $\pi^+ A \to \pi^+\pi^{\pm} A'$ were studied on $^{2}H$, $^{12}C$, $^{40}Ca$, and $^{208}Pb$ nuclei at an incident pion energy of $T_{\pi^{+}}$=283 MeV. Pions were detected in coincidence using the CHAOS spectrometer. The experimental results are reduced to differential cross sections and compared to both theoretical predictions and the reaction phase space. The composite ratio $\cal C$$_{\pi\pi}^A$ between the $\pi^{+}\pi^{\pm}$ invariant masses on nuclei and on the nucleon is also presented. Near the $2m_{\pi}$ threshold pion pairs couple to $(\pi\pi)_{I=J=0}$ when produced in the $\pi^+\to \pi^+\pi^-$ reaction channel. There is a marked near-threshold enhancement of $\cal C$$_{\pi^+\pi^-}^A$ which is consistent with theoretical predictions addressing the partial restoration of chiral symmetry in nuclear matter. Furthermore, the behaviour of $\cal C$$_{\pi^+\pi^-}^A$ is well described when the restoration of chiral symmetry is combined with standard P-wave renormalization of pions in nuclear matter. On the other hand, nuclear matter only weakly influences $\cal C$$_{\pi^+\pi^+}^A$, which displays a flat behaviour throughout the energy range regardless of $A$.Comment: 30 pages, 16 figures, PS format, accepted for publication in Nucl. Phys

Charmonium Cross Sections and the QGP

In this short review we summarize experimental information and theoretical results for the low-energy dissociation cross sections of charmonia by light hadrons. These cross sections are required for the simulation of charmonium absorption through collisions with comovers in heavy ion collisions, which competes with quark-gluon plasma production as a charmonium-suppression mechanism. If the cross sections are sufficiently large these dissociation reactions may be misinterpreted as an effect of quark-gluon plasma production. Theoretical predictions for these RHIC-related processes have used various methods, including a color-dipole scattering model, meson exchange models, constituent interchange models and QCD sum rules. As the results have been largely unconstrained by experiment, some of the predictions differ by orders of magnitude, notably in the near-threshold regime that is most relevant to QGP searches.Comment: 7 pages, 11 figures. Expanded and updated version of a presentation to QNP-2002 (Juelich, 9-14 June 2002

Separase prevents genomic instability by controlling replication fork speed

Proper chromosome segregation is crucial for preserving genomic integrity, and errors in this process cause chromosome mis-segregation, which may contribute to cancer development. Sister chromatid separation is triggered by Separase, an evolutionary conserved protease that cleaves the cohesin complex, allowing the dissolution of sister chromatid cohesion. Here we provide evidence that Separase participates in genomic stability maintenance by controlling replication fork speed. We found that Separase interacted with the replication licensing factors MCM2-7, and genome-wide data showed that Separase co-localized with MCM complex and cohesin. Unexpectedly, the depletion of Separase increased the fork velocity about 1.5-fold and caused a strong acetylation of cohesin's SMC3 subunit and altered checkpoint response. Notably, Separase silencing triggered genomic instability in both HeLa and human primary fibroblast cells. Our results show a novel mechanism for fork progression mediated by Separase and thus the basis for genomic instability associated with tumorigenesis

Separase prevents genomic instability by controlling replication fork speed

Proper chromosome segregation is crucial for preserving genomic integrity, and errors in this process cause chromosome mis-segregation, which may contribute to cancer development. Sister chromatid separation is triggered by Separase, an evolutionary conserved protease that cleaves the cohesin complex, allowing the dissolution of sister chromatid cohesion. Here we provide evidence that Separase participates in genomic stability maintenance by controlling replication fork speed. We found that Separase interacted with the replication licensing factors MCM2-7, and genome-wide data showed that Separase co-localized with MCM complex and cohesin. Unexpectedly, the depletion of Separase increased the fork velocity about 1.5-fold and caused a strong acetylation of cohesin's SMC3 subunit and altered checkpoint response. Notably, Separase silencing triggered genomic instability in both HeLa and human primary fibroblast cells. Our results show a novel mechanism for fork progression mediated by Separase and thus the basis for genomic instability associated with tumorigenesis

Design and implementation of a web-based Tailored Gymnasium to enhance self-management of Fibromyalgia

The aim of this article is to describe the design and development of an online gymnasium that proposes personalized exercise videos to users affected by fibromyalgia. Fibromyalgia syndrome is a chronic condition characterized by widespread pain in muscles, ligaments and tendons, usually associated with sleep disorders and fatigue. Physical exercise is considered as an important component of non-pharmacological treatments of this pathology, and the internet is praised as a powerful resource to promote and improve physical exercise. Yet, while online personalization of health interventions to consumers must be grounded on empirically based guidelines, guidelines for fibromyalgia-targeted exercises are scant. The achievements presented in this paper are twofold. Firstly, we illustrate how we reached definition of the relevant factors for tailoring exercise videos in relation to fibromyalgia. Secondly, we explain the general framework of the application that is composed of an interview module (that investigates the determinant values of a specific user), an adaptation module (presenting the tailored set of exercises) and a logging component (used to monitor users' interactions with the website). The paper concludes with a discussion on the strengths and weaknesses of the proposed approac

Variation of hadron masses in nuclear matter in the relativistic Hartree approximation

We study the modification of hadron masses due to the vacuum polarization using the chiral sigma model, which is extended to generate the $\omega$ meson mass by the sigma condensation in the vacuum in the same way as the nucleon mass. The results obtained in the chiral sigma model are compared with those obtained in the Walecka model which includes $\sigma$ and $\omega$ mesons in a non-chiral fashion. It is shown that both the nucleon mass and the $\omega$ meson mass decrease in nuclear medium, while the $\sigma$ meson mass increases at finite density in the chiral sigma model.Comment: 10 pages, 2 figures, accepted for publication in Nucl.Phys.

Photoproduction of charm near threshold

Charm and bottom production near threshold is sensitive to the multi-quark, gluonic, and hidden-color correlations of hadronic and nuclear wavefunctions in QCD since all of the target's constituents must act coherently within the small interaction volume of the heavy quark production subprocess. Although such multi-parton subprocess cross sections are suppressed by powers of $1/m^2_Q$, they have less phase-space suppression and can dominate the contributions of the leading-twist single-gluon subprocesses in the threshold regime. The small rates for open and hidden charm photoproduction at threshold call for a dedicated facility.Comment: 5 pages 5 figures Changes: 1- Added refs 24,25; 2- Added two sentences, top of column 2 of page 3, on the definition of x, its range and the domain of validity of the mode

The pi -> pi pi process in nuclei and the restoration of chiral symmetry

The results of an extensive campaign of measurements of the pi -> pi pi process in the nucleon and nuclei at intermediate energies are presented. The measurements were motivated by the study of strong pi pi correlations in nuclei. The analysis relies on the composite ratio C_{pi pi}^A, which accounts for the clear effect of the nuclear medium on the (pi pi) system. The comparison of the C_{pi pi}^A distributions for the (pi pi)_{I=J=0} and (pi pi)_{I=0,J=2} systems to the model predictions indicates that the C_{pi pi}^A behavior in proximity of the 2m_pi threshold is explainable through the partial restoration of chiral symmetry in nuclei.Comment: accepted for publication in Nucl. Phys.