2,234 research outputs found
Six Decades of Organ Donation and the Challenges That Shifting the United States to a Market System Would Create Around the World
Evaluation of Microwave Landing System (MLS) effect on the delivery performance of a fixed-path metering and spacing system
Metering and spacing (M & S) system's algorithms described assume an aircraft two dimensional are navigation capability. The three navigation systems compared were: very high frequency omnidirectional range/distance measuring equipment (VOR/DME) and ILS, VOR/DME and + or - 40 MLS, and VOR/DME and + or - 60 MLS. Other factors studied were M & S tentative schedule point location, route geometry effects, and approach gate location effects. Summarized results are: the MLS offers some improvement over VOR/DME and ILS if all approach routes contain computer assisted turns; pilot reaction to moving the gate closer to the runway threshold may adversely affect M & S performance; and coupling en route metering to terminal scheduling transfers most of the terminal holding to more full efficient, higher altitude en route delay
The impact of analysis on bargaining in government
"1691"--handwritten on coverIncludes bibliographical references (p. 32
The C(3P) + NH3 reaction in interstellar chemistry: II. Low temperature rate constants and modeling of NH, NH2 and NH3 abundances in dense interstellar clouds
A continuous supersonic flow reactor has been used to measure rate constants
for the C + NH3 reaction over the temperature range 50 to 296 K. C atoms were
created by the pulsed laser photolysis of CBr4. The kinetics of the title
reaction were followed directly by vacuum ultra-violet laser induced
fluorescence (VUV LIF) of C loss and through H formation. The experiments show
unambiguously that the reaction is rapid at 296 K, becoming faster at lower
temperatures, reaching a value of 1.8 10-10 cm3 molecule-1 s-1 at 50 K. As this
reaction is not currently included in astrochemical networks, its influence on
interstellar nitrogen hydride abundances is tested through a dense cloud model
including gas-grain interactions. In particular, the effect of the
ortho-to-para ratio of H2 which plays a crucial role in interstellar NH3
synthesis is examined
Factors controlling the last interglacial climate as simulated by LOVECLIM1.3
The last interglacial (LIG), also identified to the Eemian in Europe, began at approximately 130 kyr BP and ended at about 115 kyr BP (before present). More and more proxy-based reconstructions of the LIG climate are becoming more available even though they remain sparse. The major climate forcings during the LIG are rather well known and therefore models can be tested against paleoclimatic data sets and then used to better understand the climate of the LIG. However, models are displaying a large range of responses, being sometimes contradictory between them or with the reconstructed data. Here we would like to investigate causes of these differences. We focus on a single climate model, LOVECLIM, and we perform transient simulations over the LIG, starting at 135 kyr BP and run until 115 kyr BP. With these simulations, we test the role of the surface boundary conditions (the time-evolution of the Northern Hemisphere (NH) ice sheets) on the simulated LIG climate and the importance of the parameter sets (internal to the model, such as the albedos of the ocean and sea ice), which affect the sensitivity of the model.
The magnitude of the simulated climate variations through the LIG remains too low compared to reconstructions for climate variables such as surface air temperature. Moreover, in the North Atlantic, the large increase in summer sea surface temperature towards the peak of the interglacial occurs too early (at ∼128 kyr BP) compared to the reconstructions. This feature as well as the climate simulated during the optimum of the LIG, between 131 and 121 kyr BP, does not depend on changes in surface boundary conditions and parameter sets.
The additional freshwater flux (FWF) from the melting NH ice sheets is responsible for a temporary abrupt weakening of the North Atlantic meridional overturning circulation, which causes a strong global cooling in annual mean. However, the changes in the configuration (extent and albedo) of the NH ice sheets during the LIG only slightly impact the simulated climate. Together, configuration of and FWF from the NH ice sheets greatly increase the magnitude of the temperature variations over continents as well as over the ocean at the beginning of the simulation and reduce the difference between the simulated climate and the reconstructions. Lastly, we show that the contribution from the parameter sets to the climate response is actually very modest
Cross-Over between universality classes in a magnetically disordered metallic wire
In this article we present numerical results of conduction in a disordered
quasi-1D wire in the possible presence of magnetic impurities. Our analysis
leads us to the study of universal properties in different conduction regimes
such as the localized and metallic ones. In particular, we analyse the
cross-over between universality classes occurring when the strength of magnetic
disorder is increased. For this purpose, we use a numerical Landauer approach,
and derive the scattering matrix of the wire from electron's Green's function.Comment: Final version, accepted for publication in New Journ. of Physics, 27
pages, 28 figures. Replaces the earlier shorter preprint arXiv:0910.427
Cellular and humoral immune responses and protection against schistosomes induced by a radiation-attenuated vaccine in chimpanzees
The radiation-attenuated Schistosoma mansoni vaccine is highly effective in rodents and primates but has never been tested in humans, primarily for safety reasons. To strengthen its status as a paradigm for a human recombinant antigen vaccine, we have undertaken a small-scale vaccination and challenge experiment in chimpanzees (Pan troglodytes). Immunological, clinical, and parasitological parameters were measured in three animals after multiple vaccinations, together with three controls, during the acute and chronic stages of challenge infection up to chemotherapeutic cure. Vaccination induced a strong in vitro proliferative response and early gamma interferon production, but type 2 cytokines were dominant by the time of challenge. The controls showed little response to challenge infection before the acute stage of the disease, initiated by egg deposition. In contrast, the responses of vaccinated animals were muted throughout the challenge period. Vaccination also induced parasite-specific immunoglobulin M (IgM) and IgG, which reached high levels at the time of challenge, while in control animals levels did not rise markedly before egg deposition. The protective effects of vaccination were manifested as an amelioration of acute disease and overall morbidity, revealed by differences in gamma-glutamyl transferase level, leukocytosis, eosinophilia, and hematocrit. Moreover, vaccinated chimpanzees had a 46% lower level of circulating cathodic antigen and a 38% reduction in fecal egg output, compared to controls, during the chronic phase of infection
Airborne Evaluation and Demonstration of a Time-Based Airborne Inter-Arrival Spacing Tool
An airborne tool has been developed that allows an aircraft to obtain a precise inter-arrival time-based spacing interval from the preceding aircraft. The Advanced Terminal Area Approach Spacing (ATAAS) tool uses Automatic Dependent Surveillance-Broadcast (ADS-B) data to compute speed commands for the ATAAS-equipped aircraft to obtain this inter-arrival spacing behind another aircraft. The tool was evaluated in an operational environment at the Chicago O'Hare International Airport and in the surrounding terminal area with three participating aircraft flying fixed route area navigation (RNAV) paths and vector scenarios. Both manual and autothrottle speed management were included in the scenarios to demonstrate the ability to use ATAAS with either method of speed management. The results on the overall delivery precision of the tool, based on a target spacing of 90 seconds, were a mean of 90.8 seconds with a standard deviation of 7.7 seconds. The results for the RNAV and vector cases were, respectively, M=89.3, SD=4.9 and M=91.7, SD=9.0
Containing Health Care Costs: Ethical and Legal Implications of Changes in the Methods of Paying Physicians
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