A LÓGICA MERCANTIL NA POLÍTICA SOCIAL DO ENSINO SUPERIOR BRASILEIRO

RESUMO: No capitalismo, as políticas sociais, são reguladas cada vez mais pelo mercado, aprofundando a lógica da rentabilidade ao capital. Sendo assim, a política de ensino superior no Brasil, tem sido implementada de modo a garantir esse processo, especialmente através de sua mercantilização. Para tanto, busca-se nesse artigo, analisar a política de ensino superior no Brasil bem como, compreender como o conjunto de medidas que foram implementadas, como REUNI, PROUNI, FIES entre outras, influem na materialização da universidade brasileira

Orientation of OLED emitter molecules revealed by XRD

We thank Dr. Lutz Wilde at Fraunhofer IPMS, Center Nanoelectronic Technologies, Dresden for carrying out the GIXRD measurements. CM acknowledges funding by the Graduate Academy of the TU Dresden and by the European Commission through a Marie Skłodowska Curie individual fellowship (703387).Thin films of the phosphorescent emitters Ir(ppy)3 and Ir(ppy)2(acac) are investigated by GIXRD and GIWAXS. Both molecules form crystalline grains and exhibit a preferred orientation that is pertained even when doped into a host.Postprin

The price of tumor control

Ipilimumab, a cytotoxic T-lymphocyte antigen-4 (CTLA-4) blocking antibody, has been approved for the treatment of metastatic melanoma and induces adverse events (AE) in up to 64% of patients. Treatment algorithms for the management of common ipilimumab-induced AEs have lead to a reduction of morbidity, e.g. due to bowel perforations. However, the spectrum of less common AEs is expanding as ipilimumab is increasingly applied. Stringent recognition and management of AEs will reduce drug-induced morbidity and costs, and thus, positively impact the cost-benefit ratio of the drug. To facilitate timely identification and adequate management data on rare AEs were analyzed at 19 skin cancer centers. Patient files (n = 752) were screened for rare ipilimumab-associated AEs. A total of 120 AEs, some of which were life-threatening or even fatal, were reported and summarized by organ system describing the most instructive cases in detail. Previously unreported AEs like drug rash with eosinophilia and systemic symptoms (DRESS), granulomatous inflammation of the central nervous system, and aseptic meningitis, were documented. Obstacles included patientś delay in reporting symptoms and the differentiation of steroid-induced from ipilimumab-induced AEs under steroid treatment. Importantly, response rate was high in this patient population with tumor regression in 30.9% and a tumor control rate of 61.8% in stage IV melanoma patients despite the fact that some patients received only two of four recommended ipilimumab infusions. This suggests that ipilimumab-induced antitumor responses can have an early onset and that severe autoimmune reactions may reflect overtreatment. The wide spectrum of ipilimumab-induced AEs demands doctor and patient awareness to reduce morbidity and treatment costs and true ipilimumab success is dictated by both objective tumor responses and controlling severe side effects

Proposta para o ensino da Educação Ambiental na Educação Básica: a revitalização de Jardins com materiais recicláveis

Anais do 35º Seminário de Extensão Universitária da Região Sul - Área temática: Meio AmbienteEducação Ambiental pode ser entendida como um processo onde o indivíduo e o coletivo estabelecem valores sociais, conhecimentos, capacidades, atitudes e aptidões voltadas para a conservação do meio ambiente. Sendo assim, a Educação Ambiental envolve o entendimento da educação cidadã, tornando-se fundamental sua abordagem no ensino básico. O trabalho teve por objetivo a revitalização de um espaço externo em uma Escola Municipal, para tornar o ambiente propício ao ensino de Educação Ambiental. Este trabalho foi desenvolvido, no município de São Vicente do Sul/RS na Escola Municipal de Ensino Fundamental Coqueiros, por acadêmicas do Curso de Licenciatura em Ciências Biológicas do Instituto Federal Farroupilha Câmpus São Vicente do Sul/RS e bolsistas do Programa de Educação Tutorial (PET-Biologia), tendo embasamento fundamental a revitalização dos jardins desta mesma escola, com a utilização de materiais recicláveis como, garrafa pet e madeira. O trabalho foi desenvolvido juntamente com a professora de Ciências da escola, com turmas de sétimo e oitavo ano do Ensino Fundamental. A atividade desenvolvida foi a construção de dois jardins verticais utilizando materiais recicláveis, e mudas de plantas para a ornamentação, onde estas foram doadas pelo setor de jardinocultura do IFFar- São Vicente do Sul. O processo de desenvolvimento deste projeto contribuiu na formação acadêmica dos discentes que desenvolveram o trabalho, pois através deste, foi possível adquirir experiência na Educação Básica, durante a formação inicial, bem como para a escola e os alunos da mesma colaborando para a abordagem deste tema transversal nas aulas de Ciências, facilitando o entendimento dos alunos sobre Educação Ambiental. Conclui-se que, atividades práticas sobre Educação Ambiental são fundamentais para a sensibilização dos alunos e comunidade escolar sobre a preservação do meio ambiente, reciclagem e reutilização dos resíduos produzidos nas residências bem como na escol

Experiências do Pibid matemática no Colégio Estadual Manoel Ribas

Anais do II Seminário Seminário Estadual PIBID do Paraná: tecendo saberes / organizado por Dulcyene Maria Ribeiro e Catarina Costa Fernandes — Foz do Iguaçu: Unioeste; Unila, 2014Ao entrar em sala de aula, o professor encontra vários desafios, dentre eles, o de formar alunos capazes de resolver problemas encontrados no seu dia-a-dia. O impacto, ao entrar em sala de aula e responder a esse desafio, é muito grande, pois cada colégio e cada turma tem realidades, sejam elas sociais, culturais, econômicas ou intelectuais, diferentes. Realidades essas que influenciam diretamente no aprendizado. Quais são as condições (de higiene, alimentação, educação, financeira, ...) que acompanham o aluno em sala de aula? A finalidade da atividade do professor em sala de aula é de conseguir desenvolver o conteúdo de forma contextualizada e de se fazer entender, a todos os alunos de igual maneira, porém, é um desafio mediante a realidade da sala de aula que muitas vezes dificulta a interação professor, aluno e conteúdo. Neste trabalho, relatamos um pouco sobre nossas primeiras impressões em sala de aula vivenciadas junto ao PIBID/UFPR, que começa dentro da Universidad

The effects of male social environment on sperm phenotype and genome integrity

Sperm function and quality are primary determinants of male reproductive performance and hence fitness. The presence of rival males has been shown to affect ejaculate and sperm traits in a wide range of taxa. However, male physiological conditions may not only affect sperm phenotypic traits but also their genetic and epigenetic signatures, affecting the fitness of the resulting offspring. We investigated the effects of male-male competition on sperm quality using TUNEL assays and geometric morphometrics in the zebrafish, Danio rerio. We found that the sperm produced by males exposed to high male-male competition had smaller heads but larger midpiece and flagellum than sperm produced by males under low competition. Head and flagella also appeared less sensitive to the osmotic stress induced by activation with water. In addition, more sperm showed signals of DNA damage in ejaculates of males under high competition. These findings suggest that the presence of a rival male may have positive effects on phenotypic traits but negative effects on DNA integrity. Overall, males facing the presence of rival males may produce faster swimming and more competitive sperm but this may come at a cost for the next generation. This article is protected by copyright. All rights reserved

The price of tumor control: an analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab network

Background: Ipilimumab, a cytotoxic T-lymphocyte antigen-4 (CTLA-4) blocking antibody, has been approved for the treatment of metastatic melanoma and induces adverse events (AE) in up to 64% of patients. Treatment algorithms for the management of common ipilimumab-induced AEs have lead to a reduction of morbidity, e.g. due to bowel perforations. However, the spectrum of less common AEs is expanding as ipilimumab is increasingly applied. Stringent recognition and management of AEs will reduce drug-induced morbidity and costs, and thus, positively impact the cost-benefit ratio of the drug. To facilitate timely identification and adequate management data on rare AEs were analyzed at 19 skin cancer centers. Methods and Findings: Patient files (n = 752) were screened for rare ipilimumab-associated AEs. A total of 120 AEs, some of which were life-threatening or even fatal, were reported and summarized by organ system describing the most instructive cases in detail. Previously unreported AEs like drug rash with eosinophilia and systemic symptoms (DRESS), granulomatous inflammation of the central nervous system, and aseptic meningitis, were documented. Obstacles included patientś delay in reporting symptoms and the differentiation of steroid-induced from ipilimumab-induced AEs under steroid treatment. Importantly, response rate was high in this patient population with tumor regression in 30.9% and a tumor control rate of 61.8% in stage IV melanoma patients despite the fact that some patients received only two of four recommended ipilimumab infusions. This suggests that ipilimumab-induced antitumor responses can have an early onset and that severe autoimmune reactions may reflect overtreatment. Conclusion: The wide spectrum of ipilimumab-induced AEs demands doctor and patient awareness to reduce morbidity and treatment costs and true ipilimumab success is dictated by both objective tumor responses and controlling severe side effects