2,380 research outputs found
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Engaging an ecovillage and measuring its ecological footprint
As ecovillages present themselves as models of low-carbon living measuring the Ecological Footprint (EF) of an ecovillage serves both to validate that claim and to examine the component features of how the EF is achieved. This article examines the first measurement of the EF of
Ireland’s only ecovillage, situated in the village of Cloughjordan in county Tipperary. The objectives here were to measure the EF of the ecovillage at the household scale and then to use the EF to provide meaningful feedback and reflective learning on human carbon intensity to the ecovillage residents. Various methods were applied in this action research to achieve high levels of engagement and potent communication of what could be learnt from the EF. This article places a
particular focus on the necessary adaptation of an original EF method, on how it was implemented in the ecovillage, on the results obtained and on how these were communicated to the residents. The bottom-up component EF method samples consumption data at source and in so
doing appoints consumption reflection and responsibility in ways the more remote compound method can not. The strategic combination of this specific quality with co-creation method aims to meaningfully engage and motivate a settlement to reduce its carbon intensity.
According to the methodology, the ecovillage residents overshoot the fair earth share by 10% needing 1.1 planets to sustain their lifestyles. It is planned that subsequent to this intervention future measurements
will show whether the overshoot has reduced
The effects of environmental stress on the physiology of growth in rainbow trout, Salmo gairderi Richardson
There is little doubt that both mammalian and teleost growth hormones can accelerate growth and increase food conversion efficiency in all commonly-reared species of salmonid fish. In those vertebrates that have been closely studied (predominantly mammals), the pituitary hormone somatotropin (GH or growth hormone) is a prime determinant of somatic growth. The hormone stimulates protein biosynthesis and tissue growth, enhances lipid utilization and lipid release from the adipose tissues (a protein-sparing effect) and suppresses the peripheral utilization of glucose. The present study is a prerequisite for future work on growth hormone physiology in salmonids and should contribute to our understanding of the mechanisms of growth suppression in stressed fish. Plasma growth hormone (GH) levels were measured in rainbow trout using a radioimmunoassay developed against chinook salmon growth hormone
A comparison of some methods for detection of safety signals in randomised controlled trials
The occurrence, severity and duration of patient adverse events are routinely recorded during randomised controlled clinical trials. This data may be used by a trial’s Data Safety Monitoring Committee to make decisions regarding the safety of treatments and in some cases may lead to the discontinuation of a trial if real safety issues are detected. Consequently the analysis of this data is a very important part of the conduct of any trial. There are many different types of adverse event and the statistical analysis of this data must take into account multiple comparison issues when performing statistical tests. Unadjusted tests may lead to large numbers of false positive results, but simple adjustments are generally too conservative and risk compromising the power to detect important treatment differences. Mathematically there are a number of different approaches to analysing safety data with general error controlling procedures, recurrent event analysis, survival analysis and other direct modelling approaches (both Bayesian and Frequentist) all being used. Recently a variety of classical (Mehrotra and Adewale, 2012) and Bayesian (Berry and Berry, 2004; DuMouchel, 2010) methods have been proposed to address this problem. These methods use possible relationships or groupings of the adverse events. We implement and compare by way of a simulation study of grouped data some of these more recent approaches to adverse event analysis and investigate if the use of a common underlying model which involves groupings of adverse events by body-system or System Organ Class is useful in detecting adverse events associated with treatments. All of the group methods detect more correct significant effects than the Benjamini-Hochberg or Bonferroni procedures for this type of data. In particular the body-system as described by Berry and Berry (2004) looks to be a worthwhile structure to consider for use when modelling adverse event data
Fidelity protocol for the Action Success Knowledge (ASK) trial: A psychosocial intervention administered by speech and language therapists to prevent depression in people with post-stroke aphasia
Introduction: Treatment fidelity is a complex, multifaceted evaluative process which refers to whether a studied intervention was delivered as intended. Monitoring and enhancing fidelity is one recommendation of the TiDIER (Template for Intervention Description and Replication) checklist, as fidelity can inform interpretation and conclusions drawn about treatment effects. Despite the methodological and translational benefits, fidelity strategies have been used inconsistently within health behaviour intervention studies; in particular, within aphasia intervention studies, reporting of fidelity remains relatively rare. This paper describes the development of a fidelity protocol for the Action Success Knowledge (ASK) study, a current cluster randomised trial investigating an early mood intervention for people with aphasia (a language disability caused by stroke). Methods and analysis: A novel fidelity protocol and tool was developed to monitor and enhance fidelity within the two arms (experimental treatment and attention control) of the ASK study. The ASK fidelity protocol was developed based on the National Institutes of Health Behaviour Change Consortium fidelity framework. Ethics and dissemination: The study protocol was approved by the Darling Downs Hospital and Health Service Human Research Ethics Committee in Queensland, Australia under the National Mutual Acceptance scheme of multicentre human research projects. Specific ethics approval was obtained for those participating sites who were not under the National Mutual Agreement at the time of application. The monitoring and ongoing conduct of the research project is in line with requirements under the National Mutual Acceptance. On completion of the trial, findings from the fidelity reviews will be disseminated via publications and conference presentations. Trial registration number ACTRN12614000979651
How many children and young people with life-limiting conditions are clinically unstable? A national data linkage study
Objective: To determine the clinical stage (stable, unstable, deteriorating or dying) for children and young people (CYP) aged 0-25 years in Scotland with lifelimiting conditions (LLCs). Design: National cohort of CYP with LLCs using linked routinely collected healthcare data. Setting: Scotland. Patients: 20 436 CYP identified as having LLCs and resident in Scotland between 1 April 2009 and 31 March 2014. Main outcome: Clinical stage based on emergency inpatient and intensive care unit admissions and date of death. Results: Over 2200 CYP with LLCs in Scotland were unstable, deteriorating or dying in each year. Compared with 1-year-olds to 5-year-olds, children under 1 year of age had the highest risk of instability (OR 6.4, 95% CI 5.7 to 7.1); all older age groups had lower risk. Girls were more likely to be unstable than boys (OR 1.15, 95% CI 1.06 to 1.24). CYP of South Asian (OR 1.61, 95% CI 1.28 to 2.01), Black (OR 1.58, 95% CI 1.04 to 2.41) and Other (OR 1.33, 95% CI 1.02 to 1.74) ethnicity were more likely to experience instability than White CYP. Deprivation was not a significant predictor of instability. Compared with congenital abnormalities, CYP with most other primary diagnoses had a higher risk of instability; only CYP with a primary perinatal diagnosis had significantly lower risk (OR 0.23, 95% CI 0.19 to 0.29). Conclusions: The large number of CYP with LLCs who are unstable, deteriorating or dying may benefit from input from specialist paediatric palliative care. The age group under 1 and CYP of South Asian, Black and Other ethnicities should be priority groups
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Novel resource saving interventions: the case of modelling and storytelling
Climate Change communication to the Public is in general presented in a negative fashion and often depicts the resultant costs and impacts as distant. Its substantial gloom together with the less immediate consequences significantly weaken responses. Narratives and stories are potent arbiters of meaningful communication and are an important vehicle for communication in our information rich lives. Importantly, they reduce jargon, gather and translate information, provide insight, reframe evidence and engage audiences. It has been argued by many observers that stories are potentially useful in driving change; presenting a way to value what is gone, expressing emotions, and helping us assert our determination to salvage something and work towards the future.
This paper details the methods utilised by the authors to generate stories and case studies in a community in Ireland over a 4 year research period. The aim of the work was to identify and assess the salience and potency of storytelling – as part of a ‘co-creation’ process – with regard to galvanising local action in the generation of sustainable models of lifestyle practice for residents. In this paper co-creation includes the planning phase of co-design and the implementation phase of co-production. The demonstration of these sustainable lifestyle practices were a strong driver for the sustainable transition of this community supporting the reduction of its ecological footprint by 28% over 4 years, evidence of which is highlighted in this paper
Developing an alcohol policy assessment toolkit: application in the western pacific
Objective: To demonstrate the development and feasibility of a tool to assess the adequacy of national policies aimed at reducing alcohol consumption and related problems. Methods: We developed a quantitative tool – the Toolkit for Evaluating Alcohol policy Stringency and Enforcement (TEASE-16) – to assess the level of stringency and enforcement of 16 alcohol control policies. TEASE-16 was applied to policy data from nine study areas in the western Pacific: Australia, China excluding Hong Kong Special Administrative Region (SAR), Hong Kong SAR, Japan, Malaysia, New Zealand, the Philippines, Singapore and Viet Nam. Correlation and regression analyses were then used to examine the relationship between alcohol policy scores and income-adjusted levels of alcohol consumption per capita. Findings: Vast differences exist in how alcohol control policies are implemented in the western Pacific. Out of a possible 100 points, the nine study areas achieved TEASE-16 scores that ranged from 24.1 points for the Philippines to 67.5 points for Australia. Study areas with high policy scores – indicating relatively strong alcohol policy frameworks – had lower alcohol consumption per capita. Sensitivity analyses indicated scores and rankings for each study area remained relatively stable across different weighting schemes, indicating that TEASE-16 was robust. Conclusion: TEASE-16 could be used by international and national regulatory bodies and policy-makers to guide the design, implementation, evaluation and refinement of effective policies to reduce alcohol consumption and related problems
Directional bias of illusory stream caused by relative motion adaptation
AbstractEnigma is an op-art painting that elicits an illusion of rotational streaming motion. In the present study, we tested whether adaptation to various motion configurations that included relative motion components could be reflected in the directional bias of the illusory stream. First, participants viewed the center of a rotating Enigma stimulus for adaptation. There was no physical motion on the ring area. During the adaptation period, the illusory stream on the ring was mainly seen in the direction opposite to that of the physical rotation. After the physical rotation stopped, the illusory stream on the ring was mainly seen in the same direction as that of the preceding physical rotation. Moreover, adapting to strong relative motion induced a strong bias in the illusory motion direction in the subsequently presented static Enigma stimulus. The results suggest that relative motion detectors corresponding to the ring area may produce the illusory stream of Enigma
Western Australian public opinions of a minimum pricing policy for alcohol: study protocol
Background: Excessive alcohol consumption has significant adverse economic, social, and health outcomes. Recent estimates
suggest that the annual economic costs of alcohol in Australia are up to AUD $36 billion. Policies influencing price have been
demonstrated to be very effective in reducing alcohol consumption and alcohol-related harms. Interest in minimum pricing has
gained traction in recent years. However, there has been little research investigating the level of support for the public interest
case of minimum pricing in Australia.
Objective: This article describes protocol for a study exploring Western Australian (WA) public knowledge, understanding,
and reaction to a proposed minimum price policy per standard drink.
Methods: The study will employ a qualitative methodological design. Participants will be recruited from a wide variety of
backgrounds, including ethnic minorities, blue and white collar workers, unemployed, students, and elderly/retired populations
to participate in focus groups. Focus group participants will be asked about their knowledge of, and initial reactions to, the
proposed policy and encouraged to discuss how such a proposal may affect their own alcohol use and alcohol consumption at
the population level. Participants will also be asked to discuss potential avenues for increasing acceptability of the policy. The
focus groups will adopt a semi-structured, open-ended approach guided by a question schedule. The schedule will be based on
feedback from pilot samples, previous research, and a steering group comprising experts in alcohol policy and pricing.
Results: The study is expected to take approximately 14 months to complete.
Conclusions: The findings will be of considerable interest and relevance to government officials, policy makers, researchers,
advocacy groups, alcohol retail and licensed establishments and organizations, city and town planners, police, and other stakeholder
organizations
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