Magnetic behaviour of PrPd2B2C

We have synthesized a new quaternary borocarbide PrPd$_{2}$B$_{2}$C and measured its magnetization, electrical resistivity and specific heat. The compound crystallizes in the LuNi$_{2}$B$_{2}$C-type tetragonal structure (space group {\it I4/mmm}). Above 100 K the magnetic susceptibility follows Curie-Weiss behavior with effective moment $\mu_{eff}$ = 3.60 $\mu_{B}$, which is very close to the value expected for Pr$^{3+}$ ions. We do not find evidence for magnetic or superconducting transition down to 0.5 K. Specific heat exhibits a broad Schottky type anomaly with a peak at 24 K, very likely related to crystal electric field (CEF) excitation. The magnetic properties suggest the presence of a singlet CEF ground state leading to a Van-Vleck paramagnetic ground state.Comment: 2 pages, 2 figure

Therapeutic approaches with intravitreal injections in geographic atrophy secondary to age-related macular degeneration: current drugs and potential molecules

The present review focuses on recent clinical trials that analyze the efficacy of intravitreal therapeutic agents for the treatment of dry age-related macular degeneration (AMD), such as neuroprotective drugs, and complement inhibitors, also called immunomodulatory or anti-inflammatory agents. A systematic literature search was performed to identify randomized controlled trials published prior to January 2019. Patients affected by dry AMD treated with intravitreal therapeutic agents were included. Changes in the correct visual acuity and reduction in geographic atrophy progression were evaluated. Several new drugs have shown promising results, including those targeting the complement cascade and neuroprotective agents. The potential action of the two groups of drugs is to block complement cascade upregulation of immunomodulating agents, and to prevent the degeneration and apoptosis of ganglion cells for the neuroprotectors, respectively. Our analysis indicates that finding treatments for dry AMD will require continued collaboration among researchers to identify additional molecular targets and to fully interrogate the utility of pluripotent stem cells for personalized therapy

Ising pyrochlore magnets: Low temperature properties, ice rules and beyond

Pyrochlore magnets are candidates for spin-ice behavior. We present theoretical simulations of relevance for the pyrochlore family R2Ti2O7 (R= rare earth) supported by magnetothermal measurements on selected systems. By considering long ranged dipole-dipole as well as short-ranged superexchange interactions we get three distinct behaviours: (i) an ordered doubly degenerate state, (ii) a highly disordered state with a broad transition to paramagnetism, (iii) a partially ordered state with a sharp transition to paramagnetism. Thus these competing interactions can induce behaviour very different from conventional ``spin ice''. Closely corresponding behaviour is seen in the real compounds---in particular Ho2Ti2O7 corresponds to case (iii) which has not been discussed before, rather than (ii) as suggested earlier.Comment: 5 pages revtex, 4 figures; some revisions, additional data, additional co-authors and a changed title. Basic ideas of paper remain the same but those who downloaded the original version are requested to get this more complete versio

Static and dynamic XY-like short-range order in a frustrated magnet with exchange disorder

A single crystal of the Co2+ based pyrochlore NaCaCo2F7 was studied by inelastic neutron scattering. This frustrated magnet with quenched exchange disorder remains in a strongly correlated paramagnetic state down to one 60th of the Curie-Weiss temperature. Below T_f = 2.4 K, diffuse elastic scattering develops and comprises 30 +/- 10% of the total magnetic scattering, as expected for J_{eff} = 1/2 moments frozen on a time scale that exceeds \hbar/\delta E=3.8 ps. The diffuse scattering is consistent with short range XY antiferromagnetism with a correlation length of 16 \AA. The momentum (Q) dependence of the inelastic intensity indicates relaxing XY-like antiferromagnetic clusters at energies below ~ 5.5 meV, and collinear antiferromagnetic fluctuations above this energy. The relevant XY configurations form a continuous manifold of symmetry-related states. Contrary to well-known models that produce this continuous manifold, order-by-disorder does not select an ordered state in NaCaCo2F7 despite evidence for weak (~12 %) exchange disorder. Instead, NaCaCo2F7 freezes into short range ordered clusters that span this manifold.Comment: 9 pages, 9 figures. This updated version features modified figures and some new discussio

Chemically gated electronic structure of a superconducting doped topological insulator system

Angle resolved photoemission spectroscopy is used to observe changes in the electronic structure of bulk-doped topological insulator Cu$_x$Bi$_2$Se$_3$ as additional copper atoms are deposited onto the cleaved crystal surface. Carrier density and surface-normal electrical field strength near the crystal surface are estimated to consider the effect of chemical surface gating on atypical superconducting properties associated with topological insulator order, such as the dynamics of theoretically predicted Majorana Fermion vortices

Insights on star formation histories and physical properties of 1.2≤z≲41.2 \leq z \lesssim 4 Herschel-detected galaxies

We test the impact of using variable star forming histories (SFHs) and the use of the IR luminosity (LIR) as a constrain on the physical parameters of high redshift dusty star-forming galaxies. We explore in particular the stellar properties of galaxies in relation with their location on the SFR-M* diagram. We perform SED fitting of the UV-NIR and FIR emissions of a large sample of GOODS-Herschel galaxies, for which rich multi-wavelength observations are available. We test different SFHs and imposing energy conservation in the SED fitting process, to face issues like the age-extinction degeneracy and produce SEDs consistent with observations. Our models work well for the majority of the sample, with the notable exception of the high LIR end, for which we have indications that our simple energy conservation approach cannot hold true. We find trends in the SFHs fitting our sources depending on stellar mass M* and z. Trends also emerge in the characteristic timescales of the SED models depending on the location on the SFR-M* diagram. We show that whilst using the same available observational data, we can produce galaxies less star-forming than usually inferred, if we allow declining SFHs, while properly reproducing their observables. These sources can be post-starbursts undergoing quenching, and their SFRs are potentially overestimated if inferred from their LIR. Fitting without the IR constrain leads to a strong preference for declining SFHs, while its inclusion increases the preference of rising SFHs, more so at high z, in tentative agreement with the cosmic star formation history. Keeping in mind that the sample is biased towards high LIR, the evolution shaped by our model appears as both bursty (initially) and steady-lasting (later on). The global SFH of the sample follows the cosmic SFH with a small scatter, and is compatible with the "downsizing" scenario of galaxy evolution.Comment: 28 pages, 26 figures, one appendix, Accepted for publication in Astronomy & Astrophysic

The Effect of Ru substitution for Ni on the superconductivity in MgCNi3-xRux

The superconductor MgCNi3 has been chemically doped by partial substitution of Ru for Ni in the solid solution MgCNi3-xRux for 0<x<0.5. Magnetic and specific heat measurements show that the Sommerfeld parameter (gamma_exp) and TC decrease immediately on Ru substitution, but that a TC above 2K is maintained even for a relatively large decrease in gamma_exp. Ferromagnetism is not observed to develop through Ru substitution, and the normal state magnetic susceptibility is suppressed.Comment: 18 pages, 13 figure