7 research outputs found
Synthesis, crystal structure, thermal analysis, and electrical properties of bis tetrapropylammonium hexachloro-dizincate compound
Get PDF
A theoretical study on the molecular structure of new organic–inorganic bis-(4-acetylanilinium) tetrachloridozincate compound
No full textChronic hepatitis B virus infection and risk of chronic kidney disease: a population-based prospective cohort study of 0.5 million Chinese adults
No full textSynthesis, molecular docking, and biological evaluation of nitroimidazole derivatives as potent urease inhibitors
No full textApplication of urine proteomics for biomarker discovery in drug-induced liver injury
No full textAbstract The leading cause of hepatic damage is drug-induced liver injury (DILI), for which currently no adequate predictive biomarkers are available. Moreover, for most drugs related to DILI, the mechanisms underlying the adverse reaction have not yet been elucidated. Urinary protein biomarker candidates for DILI have emerged in the past few years and correlate well with clinical studies for serum DILI biomarkers. The goal of this review was to investigate the use of urine as a source of protein biomarkers for drug-induced liver injury. Finally, we discuss some of the current strategies required to advance the field of biomarker discovery for DILI with respect to appropriate clinical biobanking and adequate translational research
